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OPENSEQ.org

PABA - PABB
UniProt: P00903 - P05041
Length: 640
Sequences: 1204
Seq/Len: 1.92
I_Prob: 1.00

PABA - Para-aminobenzoate synthase glutamine amidotransferase component II
Paralog alert: 0.89 [within 20: 0.07] - ratio of genomes with paralogs
Cluster includes: HIS5 PABA
PABB - Para-aminobenzoate synthase component 1
Paralog alert: 0.54 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: PABB TRPE
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution. Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on HHsearch results which uses the overall probability and per-site alignment confidence. Inter-chain contacts in the pdb are in shades of red.
1i1qA:BContact Map
1qdlA:BContact Map


Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
95_R 206_S 3.57 1.00
20_C 320_A 2.22 0.98
99_V 429_A 2.08 0.98
95_R 202_E 1.87 0.95
17_Q 315_G 1.69 0.91
30_R 119_E 1.50 0.83
125_T 304_L 1.44 0.79
173_L 304_L 1.25 0.63
54_C 203_Y 1.12 0.49
103_K 430_D 1.09 0.45
95_R 205_H 1.03 0.39
33_A 120_S 0.95 0.30
54_C 208_D 0.94 0.29
125_T 367_I 0.91 0.26
13_W 331_V 0.91 0.25
145_A 166_W 0.90 0.25
93_V 417_G 0.85 0.20
26_V 320_A 0.84 0.19
99_V 214_L 0.83 0.18
124_V 317_V 0.83 0.18
175_E 334_F 0.79 0.15
54_C 271_R 0.78 0.15
58_E 208_D 0.76 0.13
75_I 267_E 0.75 0.13
125_T 262_L 0.75 0.13
43_K 416_N 0.74 0.12
125_T 391_C 0.73 0.11
73_L 189_T 0.70 0.10
100_M 262_L 0.69 0.10
76_L 394_I 0.69 0.10
36_L 192_Q 0.69 0.09
131_V 429_A 0.69 0.09
12_T 411_T 0.69 0.09
84_A 154_L 0.67 0.08
179_Q 192_Q 0.66 0.08
84_A 113_D 0.65 0.08
99_V 208_D 0.65 0.08
115_F 440_T 0.65 0.07
174_S 331_V 0.64 0.07
99_V 209_C 0.64 0.07
39_I 138_I 0.63 0.07
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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