| UniProt: | P00903 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10682 | ||
| Length: | 187 (187) | ||
| Sequences: | 10070 | ||
| Seq/Len: | 53.85 |
| PABA
Paralog alert: 0.89 [within 20: 0.07] - ratio of genomes with paralogs Cluster includes: HIS5 PABA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 94_V | 133_E | 3.158 | 1.00 | |
| 85_M | 162_L | 3.075 | 1.00 | |
| 86_A | 132_V | 2.787 | 1.00 | |
| 92_K | 133_E | 2.628 | 1.00 | |
| 3_L | 29_K | 2.463 | 1.00 | |
| 142_D | 156_R | 2.226 | 1.00 | |
| 35_T | 38_D | 2.205 | 1.00 | |
| 142_D | 158_R | 2.171 | 1.00 | |
| 134_P | 146_W | 2.155 | 1.00 | |
| 119_A | 176_Q | 2.148 | 1.00 | |
| 19_F | 48_V | 2.123 | 1.00 | |
| 157_H | 160_W | 2.105 | 1.00 | |
| 143_V | 152_I | 2.068 | 1.00 | |
| 144_T | 156_R | 2.053 | 1.00 | |
| 82_H | 164_G | 2.044 | 1.00 | |
| 179_Q | 182_A | 2.023 | 1.00 | |
| 182_A | 186_H | 2.008 | 1.00 | |
| 4_L | 16_Y | 2.008 | 1.00 | |
| 21_E | 178_H | 1.968 | 1.00 | |
| 86_A | 155_I | 1.933 | 1.00 | |
| 40_D | 68_H | 1.928 | 1.00 | |
| 22_L | 182_A | 1.889 | 1.00 | |
| 64_D | 67_R | 1.888 | 1.00 | |
| 143_V | 146_W | 1.885 | 1.00 | |
| 66_I | 84_A | 1.847 | 1.00 | |
| 63_L | 88_A | 1.789 | 1.00 | |
| 92_K | 136_S | 1.696 | 1.00 | |
| 145_A | 154_G | 1.662 | 1.00 | |
| 63_L | 67_R | 1.621 | 1.00 | |
| 106_P | 121_P | 1.586 | 1.00 | |
| 57_D | 87_Q | 1.584 | 1.00 | |
| 176_Q | 179_Q | 1.563 | 1.00 | |
| 133_E | 136_S | 1.538 | 1.00 | |
| 86_A | 91_G | 1.52 | 1.00 | |
| 141_F | 155_I | 1.514 | 1.00 | |
| 72_R | 160_W | 1.498 | 1.00 | |
| 2_I | 46_K | 1.496 | 1.00 | |
| 155_I | 164_G | 1.485 | 1.00 | |
| 19_F | 24_A | 1.476 | 1.00 | |
| 63_L | 87_Q | 1.455 | 1.00 | |
| 49_I | 66_I | 1.436 | 1.00 | |
| 157_H | 161_D | 1.429 | 1.00 | |
| 86_A | 138_P | 1.428 | 1.00 | |
| 94_V | 131_V | 1.426 | 1.00 | |
| 76_L | 165_V | 1.401 | 0.99 | |
| 16_Y | 20_C | 1.39 | 0.99 | |
| 112_E | 156_R | 1.377 | 0.99 | |
| 137_L | 143_V | 1.354 | 0.99 | |
| 15_L | 78_V | 1.35 | 0.99 | |
| 17_Q | 20_C | 1.327 | 0.99 | |
| 93_V | 132_V | 1.32 | 0.99 | |
| 18_Y | 178_H | 1.317 | 0.99 | |
| 107_I | 124_V | 1.317 | 0.99 | |
| 106_P | 123_T | 1.308 | 0.99 | |
| 85_M | 164_G | 1.304 | 0.99 | |
| 140_C | 158_R | 1.299 | 0.99 | |
| 89_F | 162_L | 1.29 | 0.99 | |
| 104_T | 125_T | 1.277 | 0.99 | |
| 140_C | 159_Q | 1.228 | 0.98 | |
| 108_T | 146_W | 1.227 | 0.98 | |
| 132_V | 155_I | 1.225 | 0.98 | |
| 64_D | 68_H | 1.225 | 0.98 | |
| 82_H | 132_V | 1.214 | 0.98 | |
| 48_V | 76_L | 1.21 | 0.98 | |
| 141_F | 157_H | 1.206 | 0.98 | |
| 37_A | 41_A | 1.205 | 0.98 | |
| 101_H | 129_S | 1.203 | 0.98 | |
| 77_G | 85_M | 1.191 | 0.98 | |
| 67_R | 88_A | 1.183 | 0.98 | |
| 112_E | 144_T | 1.179 | 0.98 | |
| 89_F | 141_F | 1.172 | 0.98 | |
| 49_I | 62_S | 1.163 | 0.97 | |
| 52_G | 80_L | 1.152 | 0.97 | |
| 24_A | 185_L | 1.152 | 0.97 | |
| 82_H | 155_I | 1.149 | 0.97 | |
| 3_L | 39_I | 1.147 | 0.97 | |
| 38_D | 41_A | 1.134 | 0.97 | |
| 123_T | 175_E | 1.132 | 0.97 | |
| 114_V | 163_E | 1.126 | 0.97 | |
| 66_I | 75_I | 1.126 | 0.97 | |
| 122_L | 176_Q | 1.116 | 0.96 | |
| 79_C | 168_H | 1.113 | 0.96 | |
| 32_D | 61_I | 1.1 | 0.96 | |
| 147_S | 154_G | 1.096 | 0.96 | |
| 117_G | 183_N | 1.082 | 0.96 | |
| 96_A | 131_V | 1.081 | 0.95 | |
| 156_R | 163_E | 1.08 | 0.95 | |
| 7_N | 49_I | 1.079 | 0.95 | |
| 140_C | 157_H | 1.079 | 0.95 | |
| 4_L | 19_F | 1.068 | 0.95 | |
| 27_L | 44_P | 1.061 | 0.95 | |
| 37_A | 40_D | 1.054 | 0.95 | |
| 118_L | 122_L | 1.043 | 0.94 | |
| 179_Q | 183_N | 1.033 | 0.94 | |
| 29_K | 33_A | 1.025 | 0.93 | |
| 108_T | 121_P | 1.024 | 0.93 | |
| 67_R | 70_A | 1.017 | 0.93 | |
| 57_D | 92_K | 1.014 | 0.93 | |
| 134_P | 143_V | 1.011 | 0.93 | |
| 125_T | 173_L | 1.008 | 0.93 | |
| 3_L | 44_P | 1.006 | 0.93 | |
| 47_I | 69_Y | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2ywbA | 4 | 0.9733 | 100 | 0.097 | Contact Map | 0.816 |
| 3tqiA | 4 | 0.9733 | 100 | 0.1 | Contact Map | 0.83 |
| 1gpmA | 4 | 0.9733 | 100 | 0.11 | Contact Map | 0.85 |
| 2vxoA | 2 | 0.9679 | 100 | 0.124 | Contact Map | 0.805 |
| 3uowA | 2 | 0.9786 | 100 | 0.13 | Contact Map | 0.742 |
| 1qdlB | 1 | 0.9893 | 100 | 0.148 | Contact Map | 0.839 |
| 1i1qB | 1 | 0.984 | 100 | 0.158 | Contact Map | 0.717 |
| 1a9xB | 4 | 0.9519 | 100 | 0.167 | Contact Map | 0.812 |
| 2lxnA | 1 | 0.9626 | 100 | 0.18 | Contact Map | 0.653 |
| 3r75A | 2 | 0.9519 | 100 | 0.182 | Contact Map | 0.585 |
Sequence Conservation (Image Generated using WebLogo v3)