May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
KHSE - LOLB
UniProt: P00547 - P61320
Length: 517
Sequences: 285
Seq/Len: 0.64
I_Prob: 0.44
KHSE - Homoserine kinase
Paralog alert: 0.76 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: ISPE KHSE 		LOLB - Outer-membrane lipoprotein LolB
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: LOLB
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
96_L 132_L 2.02 0.44
4_V 59_A 1.92 0.36
63_N 57_A 1.60 0.17
62_E 20_T 1.44 0.11
20_L 171_V 1.35 0.08
153_L 87_N 1.34 0.08
36_V 139_I 1.30 0.07
16_G 85_L 1.23 0.06
182_V 181_Q 1.20 0.05
270_C 85_L 1.20 0.05
262_S 57_A 1.15 0.04
234_Y 126_T 1.13 0.04
171_W 52_Y 1.11 0.04
153_L 83_L 1.10 0.03
82_V 20_T 1.10 0.03
19_V 59_A 1.08 0.03
175_L 20_T 1.08 0.03
231_A 94_L 1.07 0.03
36_V 16_A 1.07 0.03
82_V 72_F 1.06 0.03
86_L 188_M 1.05 0.03
82_V 60_Y 1.05 0.03
122_R 18_V 1.05 0.03
25_T 49_L 1.05 0.03
153_L 92_T 1.05 0.03
46_L 113_Y 1.03 0.03
231_A 52_Y 1.03 0.03
187_A 116_D 1.03 0.03
232_E 86_T 1.02 0.03
165_V 150_K 1.01 0.02
268_A 91_S 1.01 0.02
83_A 173_Y 1.01 0.02
165_V 90_G 1.01 0.02
231_A 96_L 1.01 0.02
41_A 72_F 1.00 0.02
153_L 93_E 1.00 0.02
244_Q 58_F 1.00 0.02
269_L 52_Y 0.99 0.02
147_F 15_A 0.99 0.02
124_L 96_L 0.99 0.02
78_K 59_A 0.98 0.02
229_V 90_G 0.98 0.02
199_D 32_K 0.98 0.02
182_V 132_L 0.97 0.02
279_V 171_V 0.97 0.02
157_E 93_E 0.97 0.02
25_T 205_I 0.97 0.02
237_R 21_A 0.97 0.02
122_R 99_Q 0.96 0.02
246_R 173_Y 0.95 0.02
128_G 156_R 0.95 0.02
63_N 86_T 0.94 0.02
182_V 199_L 0.94 0.02
116_K 97_N 0.94 0.02
242_F 140_L 0.93 0.02
115_G 164_Q 0.93 0.02
25_T 103_V 0.93 0.02
109_A 86_T 0.93 0.02
40_A 142_L 0.93 0.02
165_V 83_L 0.92 0.02
38_V 176_Y 0.92 0.02
176_A 87_N 0.92 0.02
252_I 66_K 0.92 0.02
196_R 77_G 0.92 0.02
105_A 144_G 0.91 0.02
248_A 27_P 0.91 0.02
268_A 65_Q 0.91 0.01
117_P 12_L 0.91 0.01
174_V 173_Y 0.91 0.01
215_Y 60_Y 0.91 0.01
198_Q 45_D 0.90 0.01
153_L 52_Y 0.90 0.01
173_W 75_Q 0.90 0.01
235_R 141_G 0.90 0.01
62_E 150_K 0.89 0.01
44_F 65_Q 0.89 0.01
82_V 80_R 0.89 0.01
19_V 72_F 0.89 0.01
272_K 46_V 0.89 0.01
124_L 126_T 0.89 0.01
226_M 52_Y 0.89 0.01
190_I 54_T 0.89 0.01
147_F 119_E 0.89 0.01
247_Q 65_Q 0.89 0.01
118_L 194_G 0.88 0.01
65_V 57_A 0.88 0.01
259_I 39_W 0.88 0.01
252_I 125_L 0.88 0.01
73_C 115_A 0.88 0.01
282_W 194_G 0.87 0.01
175_L 115_A 0.87 0.01
63_N 59_A 0.87 0.01
127_M 104_Q 0.87 0.01
63_N 63_D 0.87 0.01
237_R 69_A 0.86 0.01
257_S 66_K 0.86 0.01
66_Y 29_G 0.86 0.01
18_D 143_P 0.86 0.01
96_L 106_V 0.85 0.01
282_W 117_D 0.85 0.01
147_F 158_S 0.85 0.01
46_L 86_T 0.85 0.01
163_Q 153_D 0.85 0.01
66_Y 81_Y 0.85 0.01
253_G 125_L 0.85 0.01
126_L 173_Y 0.84 0.01
177_Y 60_Y 0.84 0.01
243_R 176_Y 0.84 0.01
283_L 196_R 0.84 0.01
268_A 74_Q 0.84 0.01
63_N 94_L 0.84 0.01
43_T 116_D 0.84 0.01
200_C 83_L 0.84 0.01
174_V 176_Y 0.84 0.01
151_M 30_P 0.84 0.01
6_A 156_R 0.84 0.01
80_I 36_S 0.84 0.01
211_I 60_Y 0.84 0.01
232_E 105_L 0.83 0.01
79_Q 17_L 0.83 0.01
182_V 71_F 0.83 0.01
257_S 109_K 0.83 0.01
18_D 133_N 0.83 0.01
118_L 21_A 0.83 0.01
196_R 115_A 0.83 0.01
173_W 64_Q 0.83 0.01
71_R 173_Y 0.83 0.01
233_P 75_Q 0.83 0.01
251_E 157_L 0.83 0.01
231_A 81_Y 0.83 0.01
77_G 23_S 0.83 0.01
18_D 152_D 0.82 0.01
106_A 78_Q 0.82 0.01
190_I 152_D 0.82 0.01
176_A 67_V 0.82 0.01
83_A 45_D 0.82 0.01
196_R 139_I 0.82 0.01
180_I 92_T 0.82 0.01
41_A 100_P 0.81 0.01
264_P 67_V 0.81 0.01
119_N 18_V 0.81 0.01
273_P 132_L 0.81 0.01
164_Q 96_L 0.81 0.01
270_C 141_G 0.81 0.01
281_D 146_A 0.81 0.01
92_I 63_D 0.81 0.01
67_Q 197_I 0.81 0.01
245_A 171_V 0.81 0.01
285_K 152_D 0.81 0.01
54_D 135_L 0.81 0.01
28_D 193_G 0.81 0.01
155_I 204_W 0.81 0.01
53_A 158_S 0.81 0.01
179_G 187_N 0.80 0.01
259_I 44_Q 0.80 0.01
118_L 154_Q 0.80 0.01
25_T 99_Q 0.80 0.01
186_E 34_P 0.80 0.01
106_A 122_I 0.80 0.01
109_A 117_D 0.80 0.01
41_A 47_R 0.79 0.01
50_G 125_L 0.79 0.01
119_N 27_P 0.79 0.01
264_P 118_A 0.79 0.01
189_A 188_M 0.79 0.01
63_N 198_K 0.79 0.01
61_R 120_E 0.79 0.01
43_T 152_D 0.79 0.01
281_D 171_V 0.79 0.01
226_M 71_F 0.79 0.01
4_V 130_I 0.79 0.01
35_V 27_P 0.79 0.01
279_V 52_Y 0.79 0.01
265_T 92_T 0.78 0.01
89_N 96_L 0.78 0.01
92_I 33_S 0.78 0.01
124_L 81_Y 0.78 0.01
148_L 29_G 0.78 0.01
35_V 64_Q 0.78 0.01
28_D 144_G 0.78 0.01
182_V 52_Y 0.78 0.01
102_S 157_L 0.78 0.01
126_L 116_D 0.78 0.01
38_V 139_I 0.78 0.01
41_A 88_P 0.78 0.01
122_R 148_D 0.78 0.01
201_I 61_I 0.78 0.01
262_S 94_L 0.78 0.01
231_A 134_S 0.77 0.01
264_P 46_V 0.77 0.01
18_D 94_L 0.77 0.01
47_N 191_T 0.77 0.01
56_L 119_E 0.77 0.01
151_M 202_D 0.77 0.01
196_R 88_P 0.77 0.01
248_A 107_D 0.77 0.01
237_R 196_R 0.77 0.01
190_I 171_V 0.77 0.01
18_D 61_I 0.77 0.01
16_G 126_T 0.77 0.01
36_V 191_T 0.77 0.01
25_T 112_R 0.77 0.01
248_A 103_V 0.77 0.01
105_A 188_M 0.77 0.01
16_G 176_Y 0.77 0.01
119_N 205_I 0.76 0.01
94_S 141_G 0.76 0.01
120_D 132_L 0.76 0.01
38_V 66_K 0.76 0.01
15_V 58_F 0.76 0.01
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions (includes both intra and inter preds)
Page generated in 0.0879 seconds.