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Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [A:0182] and [T:0214]
- A F I L V M W Y D E K R H N Q S T G P C
A 0 -0.2 -0.1 0 0 0 0 -0.1 0 0 0 0.5 -0.1 -0.2 0 0 0.5 0 0 0
F 0 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0
I 0 -0.2 0.8 0 0 -0.1 0 -0.1 -0.1 -0.1 -0.1 -0.1 1 0 -0.1 -0.1 -0.4 0 0 0
L -0.1 -0.3 -0.2 -0.1 -0.1 0.1 0 0.6 -0.1 0.6 0.6 0.7 -0.5 0.3 -0.1 -0.1 -0.7 0 0 -0.1
V -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 0 0.5 -0.1 -0.1 -0.1 -0.2 0.8 0.7 -0.1 -0.1 -0.3 0 0 -0.1
M 0.1 0.3 0.2 0.3 0.3 0.9 -0.1 -0.7 -0.2 -0.2 0.2 0.1 -0.6 -0.5 0.4 -0.1 -0.4 -0.1 -0.1 0.2
W 0 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0
Y 0 1.7 -0.1 0 0 -0.1 0 -0.1 -0.1 -0.1 -0.1 -0.1 -0.2 -0.3 0 0 -0.3 0 0 0
D 0 0.2 -0.1 0 0 -0.1 0 -0.1 -0.1 -0.1 -0.1 -0.1 0 -0.3 0 -0.1 1.1 0 0 0
E -0.1 -0.3 -0.2 -0.1 -0.1 -0.3 -0.1 0.1 0.1 -0.1 -0.2 -0.1 1.8 0.4 -0.1 -0.1 0.2 -0.1 -0.1 -0.1
K 0 -0.1 0 0 0 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0.4 0 0 0
R 0 -0.1 -0.1 0 0 -0.1 0 -0.1 0 0 0 -0.1 -0.1 0.6 0 0.4 -0.2 0 0 0
H 0 -0.1 -0.1 0 0 0 0 -0.1 0.8 0.2 0 -0.1 -0.3 -0.4 0 0 0.5 0 0 0
N 0 0.2 0.2 0 0 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0 0 0 0
Q 0 -0.2 -0.1 0 0 -0.1 0 0.4 -0.1 -0.1 -0.1 -0.1 -0.3 1 -0.1 -0.1 0.2 0 0 0
S 0 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0
T 0 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0
G 0 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0
P 0 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0
C 0 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0182 0 -0.3 0.4 0.7 0.4 -0.1 -0.3 0.1 0.3 0.7 -0.1 0.1 0.2 -0.1 0.3 -0.3 -0.3 -0.3 -0.3 -0.3
0214 -0.4 0.8 0.1 -0.3 -0.3 0.2 -0.6 0 0.1 -0.1 0.1 0.2 1.1 1.1 -0.2 -0.4 0.8 -0.6 -0.6 -0.4
Select residue pair below:
i_j Score Prob
0187_0196 4.855 1.00
0165_0219 3.380 1.00
0116_0268 3.269 1.00
0194_0197 3.134 1.00
0195_0199 3.056 1.00
0078_0100 2.989 1.00
0187_0193 2.859 1.00
0161_0167 2.729 1.00
0198_0202 2.583 1.00
0105_0109 2.547 1.00
0087_0100 2.538 1.00
0271_0281 2.497 1.00
0158_0183 2.369 0.99
0052_0058 2.346 0.99
0193_0196 2.295 0.99
0134_0142 2.269 0.99
0007_0061 2.251 0.99
0128_0283 2.238 0.99
0116_0281 2.224 0.99
0289_0297 2.210 0.99
0018_0065 2.180 0.99
0106_0110 2.135 0.99
0172_0184 2.131 0.99
0078_0087 2.019 0.98
0197_0201 2.008 0.98
0162_0199 1.970 0.97
0125_0247 1.934 0.97
0162_0195 1.908 0.97
0096_0099 1.885 0.96
0055_0064 1.850 0.96
0247_0283 1.830 0.96
0132_0247 1.806 0.95
0006_0028 1.798 0.95
0107_0111 1.788 0.95
0165_0188 1.778 0.95
0264_0278 1.763 0.94
0148_0172 1.759 0.94
0032_0052 1.699 0.93
0180_0212 1.681 0.92
0080_0083 1.631 0.91
0086_0268 1.622 0.90
0055_0081 1.614 0.90
0033_0042 1.528 0.87
0087_0115 1.514 0.86
0182_0214 1.504 0.85
0140_0233 1.480 0.84
0007_0064 1.464 0.83
0132_0282 1.449 0.82
0162_0188 1.444 0.82
0293_0297 1.436 0.82
0113_0272 1.383 0.78
0132_0283 1.375 0.77
0131_0279 1.357 0.76
0150_0168 1.357 0.76
0128_0247 1.357 0.76
0116_0119 1.342 0.75
0166_0225 1.338 0.75
0158_0167 1.334 0.74
0087_0275 1.328 0.74
0032_0058 1.325 0.74
0066_0246 1.322 0.73
0008_0019 1.316 0.73
0033_0044 1.315 0.73
0024_0139 1.299 0.72
0161_0199 1.289 0.71
0114_0273 1.288 0.71
0016_0033 1.281 0.70
0236_0242 1.280 0.70
0022_0025 1.278 0.70
0112_0162 1.278 0.70
0033_0049 1.267 0.69
0090_0261 1.231 0.66
0240_0291 1.230 0.66
0131_0135 1.229 0.65
0104_0279 1.221 0.65
0065_0261 1.217 0.64
0057_0099 1.215 0.64
0195_0201 1.215 0.64
0093_0208 1.211 0.64
0009_0081 1.196 0.62
0225_0241 1.195 0.62
0102_0105 1.190 0.62
0119_0258 1.188 0.62
0125_0240 1.185 0.61
0022_0262 1.154 0.58
0114_0272 1.154 0.58
0244_0250 1.138 0.57
0168_0225 1.136 0.56
0102_0296 1.126 0.55
0133_0245 1.113 0.54
0268_0281 1.113 0.54
0009_0064 1.112 0.54
0078_0104 1.110 0.54
0167_0252 1.107 0.54
0083_0110 1.098 0.53
0050_0165 1.094 0.52
0064_0081 1.090 0.52
0165_0296 1.089 0.52
0125_0132 1.085 0.51
0191_0280 1.083 0.51
0016_0187 1.073 0.50
0022_0028 1.069 0.50
0137_0245 1.068 0.50
0172_0214 1.063 0.49
0290_0293 1.063 0.49
0119_0278 1.059 0.49
0100_0275 1.059 0.49
0021_0196 1.051 0.48
0119_0268 1.051 0.48
0009_0115 1.048 0.48
0076_0080 1.046 0.47
0291_0295 1.038 0.47
0054_0057 1.036 0.46
0022_0060 1.035 0.46
0155_0159 1.027 0.45
0044_0047 1.024 0.45
0271_0282 1.023 0.45
0198_0281 1.023 0.45
0166_0219 1.020 0.45
0157_0161 1.017 0.44
0009_0066 1.017 0.44
0090_0259 1.008 0.43
0005_0115 1.008 0.43
0157_0160 1.006 0.43
0172_0175 1.005 0.43
0055_0276 1.003 0.43
0114_0268 0.999 0.43
0066_0258 0.991 0.42
0234_0244 0.988 0.41
0102_0292 0.986 0.41
0217_0222 0.982 0.41
0107_0113 0.982 0.41
0189_0293 0.979 0.41
0161_0290 0.978 0.40
0148_0182 0.975 0.40
0133_0258 0.962 0.39
0100_0289 0.961 0.39
0101_0295 0.961 0.39
0142_0298 0.957 0.38
0129_0285 0.956 0.38
0243_0252 0.955 0.38
0131_0298 0.953 0.38
0003_0029 0.953 0.38
0174_0180 0.952 0.38
0033_0046 0.951 0.38
0162_0201 0.943 0.37
0021_0255 0.940 0.37
0142_0291 0.939 0.37
0230_0246 0.938 0.37
0103_0106 0.934 0.36
0100_0115 0.933 0.36
0129_0133 0.931 0.36
0021_0090 0.928 0.36
0115_0283 0.925 0.35
0114_0276 0.924 0.35
0112_0273 0.922 0.35
0030_0049 0.918 0.35
0001_0167 0.917 0.35
0258_0296 0.915 0.34
0101_0280 0.913 0.34
0133_0150 0.913 0.34
0005_0031 0.913 0.34
0084_0184 0.911 0.34
0148_0214 0.910 0.34
0102_0202 0.909 0.34
0133_0231 0.908 0.34
0113_0276 0.903 0.33
0096_0189 0.903 0.33
0180_0210 0.903 0.33
0019_0046 0.902 0.33
0193_0215 0.901 0.33
0168_0226 0.901 0.33
0088_0204 0.898 0.33
0292_0296 0.893 0.32
0292_0298 0.892 0.32
0081_0111 0.891 0.32
0244_0247 0.890 0.32
0182_0212 0.890 0.32
0020_0239 0.890 0.32
0153_0171 0.888 0.32
0119_0230 0.887 0.32
0005_0198 0.886 0.32
0009_0278 0.885 0.32
0036_0228 0.883 0.32
0272_0276 0.882 0.32
0001_0162 0.881 0.31
0108_0115 0.881 0.31
0022_0031 0.877 0.31
0059_0084 0.876 0.31
0279_0284 0.874 0.31
0003_0258 0.873 0.31
0022_0065 0.873 0.31
0194_0201 0.872 0.31
0153_0205 0.870 0.30
0171_0205 0.870 0.30
0004_0269 0.870 0.30
0017_0299 0.866 0.30
0150_0158 0.866 0.30
0287_0294 0.866 0.30
0150_0172 0.862 0.30
0022_0030 0.861 0.30
0264_0282 0.860 0.30
0016_0082 0.860 0.30
0088_0116 0.860 0.30
0032_0142 0.855 0.29
0041_0054 0.855 0.29
0108_0112 0.854 0.29
0081_0134 0.854 0.29
0129_0264 0.852 0.29
0023_0220 0.850 0.29
0032_0071 0.849 0.29
0128_0282 0.848 0.29
0009_0087 0.846 0.28
0092_0153 0.845 0.28
0092_0171 0.845 0.28
0024_0236 0.844 0.28
0104_0184 0.842 0.28
0141_0150 0.841 0.28
0058_0226 0.841 0.28
0133_0202 0.841 0.28
0162_0194 0.837 0.28
0087_0142 0.836 0.28
0007_0246 0.836 0.28
0034_0058 0.835 0.28
0047_0281 0.835 0.28
0092_0205 0.835 0.28
0199_0202 0.832 0.27
0271_0289 0.827 0.27
0107_0268 0.827 0.27
0086_0192 0.826 0.27
0184_0247 0.824 0.27
0292_0295 0.822 0.26
0129_0232 0.822 0.26
0109_0174 0.822 0.26
0048_0111 0.820 0.26
0050_0189 0.819 0.26
0137_0299 0.818 0.26
0218_0223 0.817 0.26
0247_0282 0.817 0.26
0049_0261 0.812 0.26
0217_0293 0.812 0.26
0284_0291 0.810 0.26
0007_0066 0.807 0.25
0094_0122 0.807 0.25
0183_0287 0.807 0.25
0216_0285 0.807 0.25
0168_0219 0.806 0.25
0271_0283 0.805 0.25
0148_0219 0.805 0.25
0065_0265 0.804 0.25
0230_0264 0.803 0.25
0261_0286 0.803 0.25
0161_0168 0.801 0.25
0099_0103 0.801 0.25
0042_0051 0.800 0.25
0001_0293 0.798 0.25
0142_0243 0.796 0.24
0225_0298 0.796 0.24
0155_0218 0.794 0.24
0192_0231 0.793 0.24
0048_0167 0.793 0.24
0091_0286 0.791 0.24
0129_0247 0.791 0.24
0176_0180 0.790 0.24
0168_0243 0.790 0.24
0100_0161 0.789 0.24
0033_0078 0.789 0.24
0003_0119 0.788 0.24
0014_0088 0.788 0.24
0128_0264 0.787 0.24
0065_0115 0.784 0.24
0081_0258 0.783 0.23
0064_0085 0.783 0.23
0115_0269 0.780 0.23
0005_0194 0.780 0.23
0015_0067 0.779 0.23
0284_0295 0.779 0.23
0156_0203 0.775 0.23
0023_0172 0.775 0.23
0258_0262 0.773 0.23
0147_0253 0.772 0.23
0050_0067 0.771 0.23
0088_0247 0.771 0.23
0068_0074 0.771 0.23
0108_0161 0.770 0.23
0071_0150 0.768 0.22
0230_0258 0.767 0.22
0134_0298 0.766 0.22
0005_0019 0.766 0.22
0150_0174 0.765 0.22
0008_0074 0.761 0.22
0009_0139 0.760 0.22
0174_0210 0.760 0.22
0162_0165 0.758 0.22
0155_0223 0.757 0.22
0142_0285 0.756 0.22
0080_0084 0.756 0.22
0260_0292 0.752 0.21
0088_0172 0.751 0.21
0071_0118 0.751 0.21
0179_0253 0.751 0.21
0088_0271 0.750 0.21
0240_0252 0.750 0.21
0110_0281 0.749 0.21
0044_0049 0.746 0.21
0035_0104 0.745 0.21
0085_0137 0.744 0.21
0167_0185 0.743 0.21
0054_0198 0.743 0.21
0020_0023 0.742 0.21
0046_0049 0.742 0.21
0158_0211 0.741 0.21
0090_0118 0.740 0.20
0024_0238 0.739 0.20
0073_0155 0.739 0.20
0167_0287 0.738 0.20
0177_0270 0.737 0.20
0007_0058 0.737 0.20
0158_0185 0.736 0.20
0042_0055 0.733 0.20
0033_0111 0.733 0.20
0134_0285 0.731 0.20
0106_0111 0.731 0.20
0194_0198 0.730 0.20
0033_0048 0.730 0.20
0119_0136 0.729 0.20
0039_0042 0.729 0.20
0006_0031 0.728 0.20
0147_0179 0.727 0.20
0052_0148 0.726 0.20
0159_0186 0.726 0.20
0016_0258 0.725 0.20
0110_0258 0.724 0.19
0142_0168 0.723 0.19
0081_0172 0.721 0.19
0188_0214 0.719 0.19
0279_0299 0.719 0.19
0061_0148 0.718 0.19
0005_0059 0.718 0.19
0104_0255 0.717 0.19
0033_0288 0.716 0.19
0105_0112 0.714 0.19
0028_0273 0.713 0.19
0102_0106 0.713 0.19
0041_0248 0.711 0.19
0271_0297 0.709 0.19
0082_0115 0.709 0.19
0065_0292 0.708 0.18
0233_0275 0.707 0.18
0104_0107 0.706 0.18
0201_0269 0.706 0.18
0087_0243 0.705 0.18
0114_0271 0.705 0.18
0113_0176 0.705 0.18
0032_0282 0.705 0.18
0155_0166 0.705 0.18
0022_0102 0.704 0.18
0058_0085 0.702 0.18
0160_0215 0.702 0.18
0125_0243 0.702 0.18
0090_0255 0.702 0.18
0032_0055 0.702 0.18
0051_0119 0.701 0.18
0144_0235 0.701 0.18
0047_0050 0.701 0.18
0081_0284 0.701 0.18
0032_0044 0.700 0.18
0116_0277 0.699 0.18
0136_0245 0.698 0.18
0127_0130 0.698 0.18
0005_0195 0.698 0.18
0166_0222 0.698 0.18
0223_0299 0.697 0.18
0132_0180 0.697 0.18
0097_0117 0.696 0.18
0011_0019 0.696 0.18
0141_0184 0.696 0.18
0230_0248 0.695 0.18
0100_0128 0.695 0.18
0064_0182 0.695 0.18
0111_0220 0.695 0.18
0071_0196 0.695 0.18
0095_0275 0.694 0.18
0038_0296 0.694 0.18
0017_0117 0.694 0.18
0186_0218 0.694 0.18
0244_0283 0.694 0.18
0025_0183 0.693 0.18
0161_0215 0.693 0.18
0182_0234 0.693 0.18
0133_0270 0.693 0.18
0053_0057 0.692 0.17
0055_0244 0.692 0.17
0128_0286 0.691 0.17
0040_0162 0.691 0.17
0064_0113 0.690 0.17
0125_0133 0.690 0.17
0009_0119 0.690 0.17
0034_0061 0.690 0.17
0246_0264 0.689 0.17
0053_0111 0.688 0.17
0018_0225 0.688 0.17
0022_0111 0.687 0.17
0089_0173 0.687 0.17
0017_0255 0.687 0.17
0016_0110 0.686 0.17
0022_0194 0.686 0.17
0142_0284 0.685 0.17
0119_0265 0.685 0.17
0135_0282 0.685 0.17
0118_0212 0.685 0.17
0148_0180 0.684 0.17
0055_0060 0.684 0.17
0104_0234 0.684 0.17
0003_0020 0.683 0.17
0230_0250 0.683 0.17
0270_0275 0.683 0.17
0023_0194 0.682 0.17
0293_0296 0.681 0.17
0024_0131 0.680 0.17
0047_0116 0.679 0.17
0154_0181 0.679 0.17
0032_0072 0.678 0.17
0026_0139 0.678 0.17
0023_0238 0.677 0.17
0177_0188 0.677 0.17
0100_0224 0.677 0.17
0081_0142 0.677 0.17
0119_0264 0.676 0.17
0136_0299 0.676 0.17
0092_0253 0.676 0.17
0150_0167 0.675 0.17
0190_0233 0.675 0.17
0104_0108 0.675 0.17
0168_0284 0.674 0.16
0243_0298 0.674 0.16
0162_0166 0.674 0.16
0066_0143 0.673 0.16
0080_0244 0.672 0.16
0032_0283 0.672 0.16
0152_0249 0.671 0.16
0049_0066 0.671 0.16
0002_0028 0.671 0.16
0165_0168 0.670 0.16
0056_0059 0.670 0.16
0242_0247 0.669 0.16
0126_0146 0.669 0.16
Local Interactions:
i_j Score Prob
0221_0222 5.129 1.00
0207_0208 4.522 1.00
0219_0220 2.854 1.00
0038_0040 2.578 1.00
0282_0283 2.488 1.00
0002_0003 1.854 0.96
0001_0003 1.769 0.94
0166_0168 1.741 0.94
0091_0093 1.708 0.93
0056_0057 1.706 0.93
0245_0247 1.634 0.91
0296_0297 1.623 0.90
0182_0184 1.542 0.87
0071_0072 1.501 0.85
0111_0113 1.451 0.82
0001_0002 1.404 0.79
0290_0292 1.358 0.76
0093_0095 1.348 0.75
0114_0115 1.346 0.75
0208_0210 1.308 0.72
0167_0168 1.307 0.72
0083_0084 1.217 0.64
0165_0166 1.206 0.63
0048_0049 1.145 0.57
0022_0024 1.108 0.54
0115_0116 1.107 0.54
0287_0289 1.102 0.53
0131_0133 1.081 0.51
0236_0238 1.061 0.49
0110_0111 1.060 0.49
0117_0118 1.033 0.46
0105_0106 1.029 0.46
0238_0240 1.027 0.45
0166_0167 1.001 0.43
0197_0198 0.987 0.41
0054_0055 0.987 0.41
0290_0291 0.985 0.41
0192_0194 0.967 0.39
0248_0250 0.960 0.39
0284_0285 0.953 0.38
0246_0248 0.945 0.37
0007_0009 0.902 0.33
0046_0048 0.894 0.33
0180_0182 0.889 0.32
0111_0112 0.881 0.31
0029_0031 0.878 0.31
0224_0225 0.876 0.31
0006_0007 0.869 0.30
0198_0199 0.860 0.30
0031_0033 0.834 0.27
0188_0190 0.831 0.27
0044_0046 0.811 0.26
0102_0103 0.800 0.25
0055_0057 0.795 0.24
0160_0161 0.790 0.24
0052_0054 0.764 0.22
0038_0039 0.762 0.22
0023_0024 0.758 0.22
0210_0212 0.742 0.21
0024_0025 0.732 0.20
0076_0078 0.718 0.19
0041_0042 0.710 0.19
0026_0028 0.709 0.19
0132_0133 0.697 0.18
0258_0259 0.691 0.17
0133_0135 0.675 0.17
0106_0107 0.669 0.16
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M D K L R ...

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