May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [K:0179] and [E:0181]
- A F I L V M W Y D E K R H N Q S T G P C
A 0 0.2 -0.4 0.2 0.6 -0.1 -0.1 -0.1 -0.1 0.2 -0.3 0 0.3 -0.1 -0.3 -0.2 -0.2 0 0 0.3
F -0.2 -0.1 0.9 -0.2 -0.3 -0.1 0 -0.1 0.1 0 -0.2 -0.1 -0.1 -0.1 -0.2 0.2 0.1 0 0 0.2
I 0.5 -0.3 0 -0.4 -0.7 -0.2 -0.1 0.5 -0.2 0.2 0.8 0.3 -0.1 0 0.1 0 -0.1 -0.1 0 -0.2
L -0.1 -0.1 0 -0.2 0.4 0 0 -0.1 0 0.4 0.3 -0.1 0 0 -0.1 -0.1 -0.2 0 0 -0.1
V 0 -0.3 -0.5 -0.6 -0.3 -0.3 -0.1 -0.1 -0.2 1.2 0.7 -0.6 0.5 -0.1 0.6 0.5 0.2 -0.1 0 0.1
M -0.1 0 -0.1 -0.1 0.1 0 0 -0.1 0 0 -0.1 -0.1 0 0 -0.1 -0.1 -0.1 0 0 -0.1
W 0.3 -0.1 -0.1 -0.2 -0.3 0 0 -0.1 -0.1 0.5 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.4 0 0 -0.1
Y -0.1 -0.2 -0.4 0 -0.2 -0.1 0 0.1 -0.1 0.1 -0.4 1.2 0.2 -0.2 0 -0.3 0.5 0 0 -0.1
D 0 -0.3 0.4 1 1.4 0.5 -0.1 0.3 -0.3 -0.4 -0.4 -0.4 -0.2 0.1 -0.4 -0.3 -0.1 -0.1 0 0
E -0.5 -0.5 0.1 0.3 0.4 -0.4 0.3 -0.8 0 -0.9 0.2 1.3 -0.4 -0.1 0.8 -0.5 0 0.7 -0.1 0.5
K -0.1 0.6 0.8 0.4 0.3 0.3 -0.1 -0.2 -0.3 0 -0.2 -0.7 -0.2 -0.3 0.6 -0.1 -0.1 -0.1 0 0.2
R -0.2 0 0.1 0.5 0 0.4 -0.3 -0.3 0.7 0.5 -0.5 0.1 -0.5 0.2 -0.2 -0.3 0.2 -0.2 -0.1 0.3
H 0.9 -0.2 -0.4 -0.2 0.1 -0.2 -0.1 0.1 -0.1 0.1 -0.3 0.1 -0.1 -0.1 -0.1 0.5 -0.1 0 0 0.2
N 0.2 0.2 -0.1 0 -0.6 -0.2 -0.1 0.2 0.2 -0.2 -0.1 -0.3 -0.1 0.6 0.1 0.5 0.1 -0.1 0 -0.4
Q -0.6 0 0.5 0 0.8 0.2 0.6 0.1 -0.3 0 0.3 -0.4 0.1 -0.2 0.5 -0.4 -0.5 -0.1 0 -0.2
S 0.1 -0.3 0.8 0.3 0.6 0.2 -0.2 -0.1 0.7 -1.2 0 -0.3 0.4 0.3 -0.1 -0.2 -0.2 -0.1 -0.1 0.5
T -0.3 0.7 -0.7 0.3 -0.6 0.1 -0.3 0.7 -0.2 0.5 0.4 0.2 0.5 -0.1 0 0.1 0.5 -0.2 -0.1 -0.4
G 0.2 0.3 0.1 0 -0.4 0.1 0 0.1 0.3 -0.4 -0.2 -0.2 -0.1 -0.1 -0.4 0.8 0.2 0 0 -0.2
P -0.1 0.4 -0.1 -0.2 -0.2 -0.1 0.4 -0.1 0 -0.2 -0.1 -0.1 0 0 -0.1 0.3 -0.1 0 0 -0.1
C 0.1 -0.1 -0.2 -0.3 -0.1 -0.1 0 -0.1 -0.1 0.1 0.4 -0.2 -0.1 0.1 0.1 -0.1 0.4 0 0 -0.2

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0179 -0.3 -0.5 0.2 -0.7 0.2 -1 -0.5 -0.2 0.3 1.6 0.3 0.5 -0.1 0.1 0.6 0.9 0.9 -0.4 -1 -0.6
0181 -0.1 -0.3 0.5 0.9 0.6 -0.2 -0.5 -0.3 -0.2 0.4 0.4 -0.4 -0.2 -0.8 0.3 0.5 0.7 -1 -1.2 0.3
Select residue pair below:
i_j Score Prob
0140_0179 1.121 0.95
0162_0179 0.736 0.61
0031_0179 0.618 0.42
Local Interactions:
i_j Score Prob
0179_0181 1.148 0.96
0177_0179 0.611 0.40
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0121 seconds.