May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [L:0167] and [V:0170]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.3 -0.1 0.2 -0.1 -0.6 -0.1 -0.1 0 -0.2 -0.3 -0.3 0.2 -0.1 -0.1 -0.1 -0.1 0.4 -0.1 0.9 0
F 0.5 0 -0.1 0 -0.3 0 -0.3 0 -0.1 -0.1 -0.1 -0.1 0.4 0 0 -0.1 0.2 -0.1 -0.1 0
I -0.4 -0.1 0.1 -0.1 -0.2 0.4 -0.7 0 -0.2 0.6 -0.2 -0.2 -0.1 0 0.3 -0.2 1.4 -0.1 -0.5 0.4
L 0.6 0.2 0.3 -0.1 -0.2 -0.1 -0.6 -0.1 -0.1 0 0.4 0.1 0.1 0.6 -0.2 0 -0.3 0.2 -0.2 -0.1
V -0.3 -0.1 -0.3 -0.1 0.5 -0.1 -0.2 0 0.2 0 0.1 0.1 -0.2 -0.1 -0.1 0.2 0.3 -0.1 -0.2 -0.1
M 0.1 0 -0.1 0 -0.2 0 -0.2 0 -0.1 0.1 0.2 0 -0.1 0 0 0.3 -0.2 0 -0.1 0
W -0.1 0 -0.1 0 0.2 0 -0.2 0 0.4 -0.1 -0.1 -0.1 -0.1 0 0 0.4 -0.1 -0.1 -0.1 0
Y -0.1 0 -0.1 0 0.2 0 -0.2 0 -0.1 -0.1 0.3 0.3 0.3 0 0 -0.1 -0.2 -0.1 -0.1 0
D -0.2 0 -0.1 0 -0.3 0 1.3 0 -0.1 -0.2 0.2 -0.1 -0.1 0.4 -0.1 -0.1 -0.2 -0.1 -0.2 0
E -0.3 -0.1 0.2 0.1 0.2 -0.1 0 -0.1 0.1 0.6 0.3 -0.3 -0.2 -0.1 -0.1 -0.2 -0.1 0.2 0.1 -0.1
K 0.1 -0.1 -0.1 -0.1 0 0 0.1 0 -0.1 0.1 -0.2 0.3 -0.1 -0.1 0.3 0.4 -0.1 -0.1 -0.2 0
R 0.4 -0.1 -0.1 0 -0.2 0 0.2 0 0.3 -0.2 0.2 -0.1 -0.1 0 -0.1 -0.1 0.1 0 -0.2 0
H 0.1 0 0 0 -0.1 0 0.2 0 0 -0.1 -0.1 0 0 0 0 0 -0.1 0 -0.1 0
N -0.1 0 0.4 0 -0.2 0 -0.2 0 -0.1 -0.1 0.3 -0.1 0 0 0.4 0 -0.2 0 -0.1 0
Q -0.1 -0.1 -0.2 -0.1 0.2 -0.1 -0.5 0 -0.2 0.1 -0.3 0.1 -0.1 -0.1 0.4 -0.2 0.2 0.9 0.2 0
S -0.1 -0.1 0.1 0.2 0.3 -0.1 0.9 -0.1 -0.3 0.2 0 -0.1 -0.2 -0.1 -0.2 -0.2 -0.7 0 1.2 -0.1
T -0.1 0.3 -0.2 -0.1 0.2 -0.1 0.1 -0.1 0.5 -0.2 -0.4 0.3 0.2 -0.1 -0.1 0.2 0.1 -0.1 -0.4 -0.1
G -0.1 0 -0.1 0 0 0 0.2 0 0.3 0.3 -0.2 0.3 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 0.1 0
P 0 -0.1 0.1 0.5 0.7 0.3 0.2 -0.1 0.1 -0.3 -0.4 -0.2 -0.2 -0.1 -0.1 -0.2 -0.4 -0.2 0.6 -0.1
C 0 0 0 0 -0.1 0 -0.1 0 0 0 0 0 0 0 0 0 -0.1 0 -0.1 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0167 0.3 -0.5 0.4 1 0.2 -0.5 -0.7 -0.6 -0.3 0.5 0.1 -0.4 -1 -0.7 0.3 0.8 0.4 -0.2 0.5 -1.2
0170 0.6 -0.5 0.1 -0.6 1.2 -0.6 0.8 -0.7 0.1 0.4 0.5 -0.1 -0.3 -0.6 -0.2 0 0.9 -0.5 0.8 -1
Select residue pair below:
i_j Score Prob
0167_0170 0.547 0.31
Local Interactions:
i_j Score Prob
0169_0170 0.671 0.50
0170_0172 0.645 0.46
0168_0170 0.539 0.30
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0372 seconds.