May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
DHFR Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix.
Coupling matrix for [L:0167] and [D:0169]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.3 -0.3 -0.1 -0.2 -0.1 -0.1 0 -0.1 0.5 -0.2 -0.3 -0.2 0.3 0.2 0.1 0.1 -0.1 0.3 0.1 0
F -0.1 0 0 0 0 0 0 0 0.4 -0.3 -0.1 -0.1 0 0.8 -0.1 -0.1 -0.1 -0.2 -0.2 0
I -0.1 -0.1 -0.1 0.2 -0.1 -0.1 0 -0.1 0.3 0.3 0.8 0.2 -0.2 -0.2 -0.1 -0.2 -0.2 -0.5 0 -0.1
L 0.2 -0.2 -0.1 -0.2 -0.2 -0.1 0 -0.2 0.5 0 0 0.4 0.6 -0.1 0 0.3 -0.3 -0.4 0.6 -0.1
V -0.2 -0.1 -0.1 -0.1 -0.1 0 0 -0.1 0.4 0.8 0.4 0.2 -0.1 -0.1 -0.2 -0.2 -0.1 0.1 -0.1 0
M -0.1 0 0 0 0 0 0 0 -0.1 -0.3 -0.1 0 0 0 -0.1 -0.1 0 -0.2 0.8 0
W -0.1 0.4 0 -0.1 0 0 0 0 -0.1 0.1 -0.1 0.4 0 0 -0.1 -0.1 -0.1 -0.1 -0.2 0
Y -0.1 0 0 -0.1 0 0 0 0 -0.1 0.3 -0.1 -0.1 0 0.4 0.4 -0.1 -0.1 -0.2 -0.2 0
D 0.2 -0.1 0 -0.1 0.4 0 0 0 -0.4 -0.1 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 -0.2 0.9 0 0
E 0.3 -0.2 0.3 -0.1 -0.1 -0.1 0 -0.1 0.1 0.5 0.4 -0.2 0.2 -0.2 0.2 -0.2 0.2 -0.2 -0.5 0
K -0.2 -0.1 0 -0.1 -0.1 0.2 0 -0.1 0.1 -0.1 0.2 -0.1 -0.1 -0.1 -0.2 0.2 0.2 0 0.1 0
R -0.1 -0.1 0 -0.1 0 0.2 0 0 -0.2 0.7 -0.1 -0.1 -0.1 -0.1 0 -0.1 -0.1 -0.3 0.6 0
H 0 0 0 0 0 0 0 0 0.3 -0.3 0 0 0 0 0 0 0 -0.1 0.1 0
N -0.1 0 0 0 0 0 0 0 -0.1 0.1 -0.1 0 0 0 -0.1 0.3 0 0.1 -0.2 0
Q 0.5 -0.1 -0.1 -0.1 -0.1 -0.1 0 -0.1 0.2 -0.4 0.1 -0.2 -0.1 -0.1 -0.2 0.1 0.1 0.3 0.3 0
S -0.4 0.9 -0.1 -0.2 0.6 -0.1 -0.1 0 -0.1 -0.2 0.4 0.4 -0.2 -0.3 0.3 0.2 -0.3 -0.1 -0.1 -0.1
T 0.1 -0.1 -0.1 0.2 -0.1 -0.1 0 0.1 -0.4 0.2 -0.2 0 -0.1 -0.1 0.1 0.1 0.2 0.7 0.2 0
G 0.6 -0.1 0 -0.1 -0.1 0 0 0.4 -0.1 -0.5 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.1 -0.2 0
P -0.3 -0.1 -0.1 0.6 0.2 0.1 0 -0.1 -0.1 0.1 -0.2 -0.2 -0.1 -0.1 -0.2 -0.2 0.6 1 -0.5 0
C 0 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0167 0.3 -0.5 0.4 1 0.2 -0.5 -0.7 -0.6 -0.3 0.5 0.1 -0.4 -1 -0.7 0.3 0.8 0.4 -0.2 0.5 -1.2
0169 0.3 -0.3 -0.8 -0.1 -0.6 -0.6 -1.2 -0.2 0.7 1.5 0.2 0 -0.2 -0.2 0.1 0.2 0 1 0.9 -1
Select residue pair below:
i_j Score Prob
0167_0170 0.547 0.31
Local Interactions:
i_j Score Prob
0167_0168 0.608 0.40
0167_0169 0.506 0.25
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...
Page generated in 0.0129 seconds.