May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [L:0160] and [P:0161]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.1 -0.2 0 -0.4 0 -0.1 -0.3 -0.3 0.7 0.6 -0.4 0.6 -0.3 -0.1 0 0.5 -0.2 0.5 -0.1 -0.1
F -0.2 -0.1 -0.1 -0.1 -0.1 0 -0.1 0.6 -0.3 -0.4 -0.3 -0.1 -0.1 0.5 -0.1 0 0.2 0.3 -0.1 0
I -0.1 0.5 -0.5 -0.2 -0.6 0 0.2 -0.1 0.2 0 0.8 -0.4 0.2 0.4 0.2 0.5 -0.2 0 -0.5 0.1
L 0 -0.2 -0.4 0.1 0.5 -0.1 -0.3 0 0 -0.4 -0.5 0.5 -0.3 -0.3 0.2 0.3 0.6 0.1 0.6 -0.1
V 0.1 0.2 0.1 0.1 -0.6 -0.3 0.3 -0.4 0.1 0.3 0.5 -0.2 0 0.1 -0.1 1 -0.1 0.1 0 -0.2
M -0.2 -0.1 0.3 0.3 -0.1 0 -0.1 0.1 0.9 -0.2 -0.3 -0.2 -0.1 0.2 0.4 -0.5 -0.2 -0.2 -0.2 0
W -0.2 -0.1 0.2 -0.1 0.3 0 -0.1 0.5 -0.3 -0.2 -0.2 0.6 -0.1 -0.1 -0.1 -0.4 -0.2 -0.2 -0.2 -0.1
Y 0 0.3 0.2 -0.1 -0.1 0 -0.1 -0.1 0.2 0.5 0.1 0.1 -0.1 -0.2 -0.2 -0.1 -0.2 -0.2 -0.3 -0.1
D -0.6 -0.1 -0.2 0.5 0.3 -0.1 0.1 0.1 -0.1 0.2 0.6 -0.4 0.5 -0.5 0.2 -0.7 -0.1 0 1 0.2
E -0.4 -0.2 0.5 0.3 0.1 -0.1 -0.3 -0.4 0.2 -0.2 0.3 -0.4 0.3 0.1 0 0.8 0.2 -0.6 -0.3 0.5
K 0.1 0.3 0.3 0.1 0.4 0.4 -0.2 0.1 -0.5 0.3 -0.1 0 -0.2 0 -0.3 0.3 0.1 0 -0.3 -0.1
R 0.1 -0.1 0.3 0.1 0.4 -0.1 -0.2 0 -0.2 0 0.6 0.4 -0.2 -0.3 -0.3 -0.4 0 0 0 -0.1
H 0.5 0 -0.1 -0.1 -0.1 0 -0.1 -0.1 0.2 -0.4 -0.2 0.6 0.4 -0.1 -0.1 -0.4 -0.2 -0.2 0.5 0
N 0 -0.1 0.1 -0.1 -0.1 0 0.3 -0.1 -0.3 0.3 -0.1 0.2 -0.1 0 -0.2 0 0.2 0.6 -0.2 0
Q -0.3 0.3 -0.2 -0.2 -0.2 0 0.2 -0.1 0.2 0.3 -0.2 0.1 -0.2 0 0.1 -0.3 -0.2 -0.1 1.4 -0.1
S 0.2 -0.1 -0.3 -0.2 0.1 -0.1 0.2 0.7 0.3 0.3 -0.3 -0.4 0.2 -0.1 0 0 0 -0.1 0 -0.1
T 0.8 -0.4 -0.1 -0.1 -0.5 0.1 0.4 0.1 -0.3 0 0.4 -0.2 0.5 0.1 0.5 -0.1 -0.1 0.4 -0.4 -0.3
G 0.2 0 -0.1 0.3 -0.1 0 -0.1 -0.1 0 -0.5 0.1 -0.1 -0.1 0.6 0.2 0 -0.1 -0.1 -0.1 0
P -0.1 0 0 0 0 0 0 0 -0.1 -0.1 -0.1 0 0 0 0 -0.1 0 0 0 0
C -0.2 0 -0.1 -0.1 -0.1 0 -0.1 -0.1 0.2 0.3 -0.2 -0.1 -0.1 0.2 -0.1 0.2 -0.1 -0.1 -0.1 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0160 0.5 -0.8 1.1 0.4 1.6 -0.7 -0.5 -0.3 0.3 0.7 0 0 -0.6 -0.4 0.1 0.2 1.3 -0.8 -1.7 -1.1
0161 0.6 -0.7 0.1 0 0 -1.1 -0.5 0 0.7 1.1 0.3 0.4 -0.2 0 0.2 0.9 0.1 0.2 0.2 -0.8
Select residue pair below:
i_j Score Prob
0034_0161 0.545 0.31
Local Interactions:
i_j Score Prob
0161_0162 0.982 0.88
0161_0163 0.762 0.64
0160_0161 0.696 0.54
0159_0161 0.533 0.29
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0753 seconds.