May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [M:0126] and [I:0152]
- A F I L V M W Y D E K R H N Q S T G P C
A -0.1 0 -0.3 0.5 -0.4 -0.2 -0.2 -0.3 0.3 0.1 0.3 -0.1 -0.1 -0.2 -0.1 1.3 -0.1 -0.1 0.1 0
F 0.2 0.2 0.2 0.1 -0.5 0.6 0.3 0.4 -0.3 0.1 -0.1 -0.1 -0.1 -0.2 -0.1 -0.2 -0.1 -0.1 0 0
I -0.3 0.5 0.4 -0.4 1.1 -0.1 -0.5 0.5 0.6 0.1 -0.2 -0.2 -0.1 0.1 -0.2 -0.4 -0.2 -0.2 0.3 -0.1
L -0.2 0 0.1 0.1 0.8 0.1 0.2 0 0 -0.3 -0.1 0.6 0.1 0 -0.7 -0.4 0.6 0.3 -0.2 -0.1
V -0.1 -0.4 0.3 0.3 -0.3 0.5 -0.1 0.6 -0.2 -0.1 -0.1 -0.1 0 -0.1 0.4 -0.1 -0.1 -0.1 0.1 0
M 0.3 -0.1 0.8 -0.6 1.3 -0.2 0 0.2 0.3 -0.2 -0.3 -0.3 -0.2 0.4 -0.1 -0.3 -0.1 0.1 -0.3 -0.1
W -0.1 0.1 -0.1 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 0.3 0 0 0 -0.1 0 -0.1 0.4 0 0.3 0
Y -0.1 -0.2 0.4 0 0.1 0.3 -0.1 -0.1 -0.2 -0.1 -0.1 0 0 -0.1 0 0.3 -0.1 0 0.1 0
D 0 -0.2 -0.2 0.7 -0.1 0 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 0 0 -0.1 0
E -0.1 1.5 -0.1 -0.4 -0.3 -0.1 -0.1 -0.2 -0.2 0.2 -0.1 0.2 0 0.3 -0.1 -0.1 -0.1 0 -0.2 0
K -0.1 0.1 0.1 1.3 -0.2 -0.1 -0.2 -0.2 -0.1 -0.1 0 0 0 -0.1 -0.1 -0.1 0 0 0.2 0
R 0 -0.2 0.6 -0.4 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0 0 0 -0.1 0 0 0 0.2 -0.1 0
H 0.4 0.1 0 -0.1 -0.1 0 -0.1 0 -0.1 -0.1 0 0 0 -0.1 0 0 -0.1 0 -0.1 0
N 0 0.2 -0.3 0.1 -0.1 -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 -0.1 0
Q -0.1 -0.6 -0.5 -0.2 -0.3 0 1.7 -0.2 0.1 -0.2 -0.1 -0.1 0 -0.1 0.5 -0.1 -0.1 -0.1 0.5 0
S 0 0.1 -0.1 -0.3 -0.1 -0.1 -0.1 -0.1 0.2 0.7 0 0 0 0.2 -0.1 -0.1 0 -0.1 -0.1 0
T 0 -0.2 0.1 0 -0.1 0 0 -0.1 -0.1 0 0 0 0 0 0 0.4 0 0 -0.1 0
G 0 0.1 -0.1 -0.2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
P 0 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
C 0 -0.1 -0.2 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0126 0.4 0.7 1.5 2.6 0.3 1.5 -0.1 0.4 -0.9 0.2 0.1 -0.7 -0.7 -0.6 -0.1 -0.4 -0.6 -1.1 -1.2 -1.1
0152 -0.4 1.1 0.7 0.8 0.1 0.1 0.3 0.2 0.4 0.2 -0.3 -0.6 -0.8 0.4 -0.2 0.2 -0.3 -0.5 0.4 -1
Select residue pair below:
i_j Score Prob
0134_0152 1.840 1.00
0126_0152 0.663 0.49
0011_0152 0.623 0.42
0062_0152 0.609 0.40
Local Interactions:
i_j Score Prob
0152_0153 1.047 0.92
0151_0152 0.558 0.32
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.2232 seconds.