May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
DHFR Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix.
Coupling matrix for [A:0125] and [N:0127]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.3 0 -0.2 -0.1 0.2 0.4 -0.2 -0.1 -0.3 -0.3 0.3 0.7 -0.3 -0.3 0.7 0.2 -0.2 0 -0.1 -0.1
F -0.3 -0.2 -0.1 -0.2 -0.2 -0.2 -0.1 0 0.8 -0.1 0.2 -0.2 -0.3 0.3 -0.2 0.1 0 0.2 0.9 -0.1
I -0.2 0 0 0 0 0 0 0 -0.3 0.3 0.3 -0.1 -0.1 0.5 -0.1 -0.1 -0.1 -0.1 -0.4 0
L -0.1 -0.2 -0.1 0.1 -0.1 -0.2 -0.1 -0.1 0.8 -0.5 -0.4 0.2 0.1 0.1 -0.5 0.1 -0.1 0.2 1 -0.1
V -0.2 -0.1 0 -0.1 -0.1 -0.1 0 0 0.5 0.4 0 -0.3 0.9 0 0.4 0 -0.2 0.2 -0.6 0
M 0.6 -0.1 0 -0.1 0 -0.1 0 0 -0.1 0.5 -0.3 -0.3 -0.1 -0.6 -0.2 0.6 -0.2 0.1 0.7 0
W -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0 -0.1 0 0 0 0 0.4 0
Y -0.3 0 0 -0.1 0 0 0 0 0.3 0.2 0.3 -0.2 0.3 0.2 0.1 -0.2 -0.1 -0.2 0.1 0
D 0 0 0 0.4 0 0 0 0 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 -0.1 0
E -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0 -0.1 0 0 0 0 0.2 0
K 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 -0.1 0
R 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 -0.1 0
H 0 0 0 0 0 0 0 0 0.3 -0.1 0 0 0 -0.1 0 0 0 0 -0.1 0
N 0 0 0 0 0 0 0 0 -0.1 0.3 0 0 0 -0.1 0 0 0 0 -0.2 0
Q 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 -0.1 0
S -0.1 -0.1 0 0.5 -0.1 -0.1 0 -0.1 -0.6 -0.1 0.1 0 -0.2 0.4 0.3 -0.1 0.5 -0.3 -0.3 0
T 0.4 0.6 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 0.5 0.3 -0.4 -0.2 -0.1 0.2 -0.1 -0.3 0 0.3 -0.3 -0.1
G 0.5 -0.1 0 -0.1 0 -0.1 0 0 -0.5 0.1 0.9 -0.1 0.1 -0.1 0.3 0 0.6 0 -0.8 0
P 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 -0.1 0
C 0.1 -0.1 0 -0.1 0 -0.1 0 0 -0.1 0.1 -0.3 0.8 -0.1 0.2 -0.2 0.2 -0.2 -0.2 0.4 0
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0125 1 0.6 -0.1 1.2 0.4 0.8 -0.5 0.2 -0.5 -0.6 -0.7 -0.7 -0.5 -0.5 -0.7 0.6 0.8 0.3 -0.7 0.1
0127 0.8 -0.7 -1.2 -0.3 -0.9 -1 -1.2 -1 1.4 1.4 0.8 0.2 -0.1 1.1 0.5 0.4 0.1 0.3 0.7 -1.1
Select residue pair below:
i_j Score Prob
0094_0125 2.350 1.00
0097_0125 1.877 1.00
0115_0125 1.492 1.00
0076_0125 1.180 0.97
0005_0125 0.781 0.67
0052_0125 0.632 0.44
0007_0125 0.518 0.27
Local Interactions:
i_j Score Prob
0125_0127 0.573 0.35
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...
Page generated in 0.0097 seconds.