May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [I:0115] and [A:0125]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.1 -0.3 0 1.4 -0.1 -0.2 0 -0.1 0 0 0 0 0 0 0 -0.1 -0.2 -0.1 0 -0.1
F 0.5 -0.2 0 -0.3 0.3 -0.2 0 0.2 0 0 0 0 0 0 0 -0.1 0.1 -0.1 0 -0.1
I 0.1 1 -0.2 -1.1 0.5 -0.6 0 0.3 0.1 -0.3 -0.1 -0.1 -0.2 0.1 -0.1 0.7 0.7 0.5 -0.1 0.4
L 0 -0.2 0.2 0.3 -0.5 0.3 -0.1 0.3 0 0 0 0 0 0 0 0 -0.3 0.9 0 0.1
V 0.5 1.1 0.2 0.5 0.2 -0.2 0 -0.2 -0.2 0.1 -0.1 -0.1 0.1 -0.2 -0.1 0.4 0.7 -1.1 -0.1 0.3
M 0.3 0.5 0 -0.2 -0.1 -0.1 0 -0.1 0 0 0 0 0 0 0 -0.1 -0.1 -0.1 0 -0.1
W -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Y 0.1 -0.1 0 -0.2 0.4 -0.1 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0
D -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
E -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
K -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
R -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
H -0.1 -0.2 0 0.2 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
N 0 -0.1 0 -0.3 -0.1 -0.2 0 -0.1 0 0 0 0 0 0 0 -0.1 0.3 0.7 0 0
Q -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
S -0.2 -0.1 0 -0.2 0 0.6 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0
T -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
G -0.8 -0.3 -0.1 0.8 -0.2 1.5 0 -0.1 0 0 0 0 0 0 0 -0.1 -0.3 -0.2 0 -0.1
P -0.1 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
C 1.1 -0.3 0 0.4 -0.1 -0.1 0 -0.1 0 0 0 0 0 0 0 -0.1 -0.1 -0.1 0 -0.2

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0115 0.5 0.1 2.7 1.9 2.8 -0.2 -0.8 -0.4 -0.8 -0.8 -0.8 -0.8 -0.6 0 -0.8 -0.4 -0.7 -0.1 -0.8 0.6
0125 1 0.6 -0.1 1.2 0.4 0.8 -0.5 0.2 -0.5 -0.6 -0.7 -0.7 -0.5 -0.5 -0.7 0.6 0.8 0.3 -0.7 0.1
Select residue pair below:
i_j Score Prob
0115_0125 1.492 1.00
0052_0115 0.635 0.44
0115_0139 0.510 0.26
Local Interactions:
i_j Score Prob
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.4152 seconds.