May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [N:0108] and [K:0109]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.9 -0.2 -0.2 0 -0.3 -0.1 -0.1 -0.2 0.1 0.1 0 -0.2 0.6 0.1 0.4 -0.4 0.2 0.4 -0.2 -0.1
F 0.1 -0.1 -0.1 0.1 -0.1 0 0 -0.1 0 0.1 -0.1 -0.2 -0.1 0.2 -0.2 0.6 0.2 -0.5 -0.1 0
I -0.2 -0.1 -0.1 -0.1 -0.1 0 0 0 -0.3 -0.2 0.2 -0.2 -0.1 0.1 0.7 -0.1 0.2 -0.2 0.2 0
L -0.3 -0.1 -0.2 -0.3 -0.2 -0.1 -0.1 0.3 -0.7 -0.1 -0.1 0.3 -0.2 0.8 0.1 0.8 0.2 0.7 -0.2 -0.1
V 0 -0.1 -0.1 -0.2 0.3 0 0 -0.1 -0.3 0 0.3 -0.3 -0.1 0.3 -0.1 -0.3 -0.3 0.2 0.5 0.4
M -0.2 0 0 -0.1 -0.1 0 0 0 0.1 0.2 0.1 -0.1 -0.1 -0.2 0.2 -0.1 -0.1 -0.1 0.1 0
W -0.1 0 0 -0.1 0 0 0 0 -0.1 0.3 -0.2 -0.1 0 -0.1 -0.1 -0.2 -0.1 0.1 0.2 0
Y -0.2 0 -0.1 -0.1 -0.1 0 0 0 -0.3 -0.2 0 -0.1 0.7 0.2 -0.2 0.3 -0.2 -0.5 0.5 0
D 0.3 -0.2 0.2 0.1 0.1 -0.1 -0.1 -0.2 1.2 -0.3 0.4 0.3 -0.4 -0.2 -0.3 0.3 0.2 -0.2 -0.7 -0.1
E -0.2 -0.2 -0.2 0.4 -0.3 0 0.3 -0.1 -0.4 0.5 0.1 0.9 -0.3 0.1 -0.2 -0.1 -0.2 0.4 0 -0.1
K -0.1 -0.1 -0.2 0.4 -0.3 -0.1 -0.1 -0.1 0.3 0 0.3 0.4 0.1 0 -0.1 0 0.3 -0.2 -0.2 -0.1
R 0.5 -0.1 0.3 0.2 -0.2 -0.1 -0.1 0.3 -0.1 -0.2 -0.2 0 -0.2 0.4 -0.1 -0.2 -0.4 0.2 0.1 0.3
H 0.1 0.2 -0.2 -0.1 0 -0.1 -0.1 -0.2 -0.1 0.2 0.2 -0.2 -0.3 -0.6 1.1 0.1 -0.3 -0.4 1 -0.1
N -0.4 0.2 0 0 -0.3 -0.1 -0.1 -0.2 0.2 -0.1 0.1 -0.5 0.1 0.2 0.5 0.3 0.5 -0.5 0.9 0
Q 0.8 -0.1 -0.1 0.2 -0.2 -0.1 0 0.3 0.5 -0.2 0.3 -0.4 0.2 -0.2 -0.4 -0.3 0.2 0.2 -0.2 -0.1
S -0.2 0.5 0.1 -0.2 0.5 0 -0.1 -0.2 0.1 0 -0.4 0.7 0.3 -0.5 -0.4 0.4 -0.1 -0.3 0 -0.1
T 0.3 -0.1 0 -0.2 -0.1 -0.1 0 -0.1 0.3 -0.4 0.3 0 -0.2 0 -0.2 0.2 -0.3 0.3 0.1 -0.1
G 0.1 -0.1 0.4 0 1.1 -0.1 -0.1 -0.1 0.3 -0.4 0.6 0.2 0.1 -0.5 -0.2 -0.8 0.3 0.2 -0.7 -0.1
P -0.4 -0.1 -0.1 0.4 -0.2 -0.1 -0.1 -0.1 -0.1 0.9 -0.7 0.2 0.1 0.1 -0.2 -0.4 -0.4 0.9 0 -0.1
C -0.1 0 0 -0.1 0.4 0 0 0 0.2 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 0.1 -0.1 -0.4 0.1 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0108 0.7 -0.8 -0.7 0.1 -0.3 -1 -1.4 -0.9 0.7 0.7 0.3 0.2 0.5 0.4 0.1 0.7 -0.1 0.1 0.1 -1.3
0109 0.5 -1 -0.8 -0.1 -0.4 -1.4 -1.6 -1.1 0.9 0.6 1.1 0.2 -0.4 0.5 0.4 1 0.2 1.5 1.2 -1.4
Select residue pair below:
i_j Score Prob
Local Interactions:
i_j Score Prob
0109_0110 0.587 0.37
0108_0109 0.530 0.29
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0183 seconds.