May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
DHFR Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix.
Coupling matrix for [T:0101] and [E:0155]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.1 0.6 0.2 -0.2 0.3 -0.1 -0.2 -0.3 -0.4 0 -0.6 1 -0.1 -0.2 0.1 -0.3 0.3 1.4 -0.8 -0.1
F 0.1 -0.1 -0.1 -0.1 -0.1 0 0 0 -0.2 -0.3 -0.2 -0.1 -0.1 0.4 -0.1 1 0.2 -0.2 -0.1 0
I -0.5 0.2 -0.1 0.1 -0.1 0 -0.1 -0.1 0.4 -0.6 -0.1 0.2 -0.2 0.7 0 0.2 0.3 0.2 -0.2 -0.1
L 0 -0.2 -0.3 0.6 -0.6 -0.1 -0.3 0.1 0.3 0.3 -0.3 -0.2 0.2 0.4 -0.2 0.5 0.5 0.2 0.3 0.1
V -0.3 -0.1 -0.1 0.2 -0.1 0 0 0 0.7 0.1 0.8 -0.1 0 0 -0.2 -0.5 0.6 -0.3 -0.2 -0.1
M 0.2 0 0.4 -0.1 0 0 0 0 -0.3 -0.2 -0.1 -0.1 0.8 -0.2 -0.1 -0.3 -0.1 -0.1 0.3 0.2
W 0 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0 0 0 -0.1 0 0 0 0
Y -0.3 0.2 -0.1 0.4 0.3 0 0.7 0.4 -0.3 -0.4 0.1 -0.2 -0.2 0.5 -0.3 0.6 0 -0.4 -0.2 -0.1
D -0.1 0 0 0 0 0 0 0 -0.2 0.2 -0.1 0 0 0.3 -0.1 -0.2 -0.1 -0.1 -0.1 0
E -0.1 0 0 0 0 0 0 0 -0.2 0.4 -0.1 0 0 -0.1 -0.1 -0.1 -0.1 -0.1 0 0
K -0.1 0 0 -0.1 0 0 0 0 -0.4 0.4 0.1 0.1 0 0.3 0.4 -0.2 -0.1 -0.1 -0.1 0
R -0.1 0 0 0 0 0 0 0 0.5 -0.2 -0.1 0 0 -0.1 -0.1 -0.2 -0.1 0.1 -0.1 0
H -0.1 0 0 0 0 0 0 0 -0.2 -0.1 -0.1 0 0 -0.1 -0.1 -0.1 -0.1 -0.1 0 0
N -0.1 0 0.4 -0.1 0 0 0 0 -0.2 0.2 0.2 0.4 0 -0.1 -0.1 -0.2 -0.1 -0.1 -0.1 0
Q -0.2 0 0 -0.1 0 0 0 0 -0.5 -0.3 -0.2 -0.1 -0.1 -0.2 0.2 0 -0.1 0.1 -0.1 0
S 0.3 -0.1 0 -0.1 -0.1 0 0 0 0.5 0.1 -0.1 -0.1 -0.1 0.2 0.3 0.1 -0.1 -0.2 -0.1 0
T 0.1 -0.1 0 -0.1 -0.1 0 0 0 0.4 0.4 0.7 -0.1 -0.1 -0.2 -0.2 0.3 -0.2 -0.2 -0.1 0
G 1 -0.1 0 -0.1 -0.1 0 0 0 -0.1 0.3 -0.2 -0.1 -0.1 -0.2 -0.1 -0.1 -0.2 0.2 0.2 0
P 0.5 0 0 0 0 0 0 0 -0.2 -0.2 -0.1 0 0 -0.1 -0.1 0.2 -0.1 -0.1 -0.1 0
C -0.3 -0.1 -0.1 0.2 0.3 0 0 0 0.9 0 0.2 -0.1 -0.1 0 0.5 -0.5 -0.2 -0.2 -0.2 -0.1
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0101 2.2 0 0.8 2.6 0.4 -0.4 -1.3 0.8 -0.7 -0.9 -0.5 -0.8 -1 -0.8 -0.5 -0.2 0 -0.2 -0.8 0.3
0155 0.5 -0.6 -0.9 -0.2 -0.8 -1.5 -1.1 -1 1.4 1.3 0.4 -0.3 -0.4 0.6 0.3 0.7 0.2 0.6 -0.3 -0.9
Select residue pair below:
i_j Score Prob
0099_0155 0.523 0.28
0101_0155 0.513 0.26
Local Interactions:
i_j Score Prob
0153_0155 0.828 0.74
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...
Page generated in 0.0168 seconds.