May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
DHFR Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix.
Coupling matrix for [L:0090] and [R:0092]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.4 -0.1 0 -0.1 -0.1 -0.1 0 -0.3 0.1 -0.2 0.1 -0.6 0 0.1 0.1 0.2 -0.4 0.5 0.7 -0.1
F -0.2 -0.1 0 -0.1 -0.1 -0.1 0 0.1 0.2 0 0.2 0 -0.8 0.1 0.2 0.2 0.7 -0.4 0.1 -0.1
I -0.2 -0.2 -0.1 -0.2 -0.2 -0.2 -0.1 -0.4 -0.2 -0.1 -0.1 0.5 1.2 0.3 -0.2 0 -0.3 0.5 0.2 0.1
L -0.1 -0.1 -0.1 -0.2 -0.2 -0.1 -0.1 0.4 -0.1 -0.1 0 0.4 1 1 0.2 -0.2 0.1 -0.3 -0.2 -0.2
V -0.1 0.2 -0.3 -0.3 0.1 0 0.1 -0.7 0.3 0.1 -0.3 0.7 1.5 0.5 -0.1 0.1 0 0.1 0.1 -0.1
M 0.1 0 0 0 0 0 0 0.3 -0.2 -0.1 -0.2 -0.2 0.6 -0.1 -0.1 -0.1 -0.3 0.3 -0.2 0
W -0.3 0 0 -0.1 -0.1 0 0 -0.1 -0.3 -0.1 0.1 0.4 -0.4 0 -0.1 0.1 0 -0.1 0.5 -0.1
Y -0.3 -0.1 0 -0.1 -0.1 -0.1 0 -0.2 0 0.1 0.6 -0.3 -0.5 -0.1 -0.1 -0.2 0.2 -0.1 0.5 0.4
D -0.1 0 0 0 0.4 0 0 0 0.6 -0.1 -0.1 -0.1 -0.2 -0.2 -0.1 -0.2 -0.1 0.2 -0.2 0
E -0.2 0 0 0 0 0 0 -0.1 -0.1 -0.1 -0.2 -0.2 0 -0.2 -0.1 -0.4 0.2 0.1 -0.2 0.4
K -0.2 0 0 0 0 0 0 1.2 0.3 -0.1 -0.2 -0.2 -0.4 0.6 -0.1 -0.2 -0.3 0.3 -0.2 0
R 0.6 0.4 0 0.3 -0.1 0.4 0 -0.2 -0.4 0.2 -0.2 -0.2 -0.5 -0.6 -0.1 0.5 -0.3 0 0.6 -0.1
H 0.2 0 0 -0.1 0.1 0 0 -0.1 0.3 -0.2 -0.1 0.3 -0.4 0.2 -0.1 0.1 -0.1 -0.3 -0.2 -0.1
N -0.1 0 0 0.3 0 0 0 0 0.2 0.3 0.2 -0.1 -0.2 -0.3 -0.1 0 -0.2 0.1 -0.2 0
Q 0.1 0.4 0 0 0 0 0 -0.1 -0.2 0.3 0.1 -0.2 0.1 -0.1 -0.1 -0.1 -0.2 0.5 -0.3 0
S -0.1 -0.1 0 -0.1 0.3 -0.1 0 -0.2 0.1 0.1 0.5 -0.4 -0.5 -0.2 0.8 -0.4 0.6 -0.3 0.2 -0.1
T 0.1 -0.1 -0.1 0.2 -0.2 -0.1 -0.1 -0.4 -0.1 -0.2 0.2 0.6 0 -0.2 -0.3 0.6 0.8 0.2 -0.3 0.2
G -0.1 0 0 0 0 0 0 -0.1 0.2 0.3 -0.1 -0.1 -0.2 -0.2 -0.1 0.3 0.2 -0.3 0.2 0
P 0.6 0 0.4 0 0 0 0 -0.1 0.2 -0.1 -0.1 -0.2 -0.3 -0.2 -0.1 0.1 0.1 0 -0.2 0
C -0.2 -0.1 0 0 0 0 0 0.2 -0.3 -0.1 0.5 0 -0.2 -0.1 -0.1 0.5 0 -0.2 -0.2 -0.1
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0090 0.3 0.5 1 1 2.2 -0.6 -0.4 0 -1 -0.6 -0.4 -0.2 -0.3 -0.8 -0.6 0.3 0.8 -0.7 -0.6 -0.5
0092 0.4 -0.6 -1 -0.5 -0.5 -0.8 -1 -0.6 0.7 0.2 0.6 0 -0.6 0.8 -0.1 1 0.5 0.4 0.6 -0.5
Select residue pair below:
i_j Score Prob
0077_0092 1.448 0.99
0092_0096 1.185 0.97
0080_0092 0.693 0.54
0079_0092 0.687 0.53
0082_0092 0.535 0.29
Local Interactions:
i_j Score Prob
0090_0092 1.117 0.95
0092_0093 0.661 0.48
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...
Page generated in 0.0376 seconds.