May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [G:0086] and [A:0087]
- A F I L V M W Y D E K R H N Q S T G P C
A 0 -0.2 -0.4 -0.5 -0.6 -0.1 0 -0.1 0.4 0.3 -0.2 -0.1 -0.2 0.1 0.2 0 -0.2 0.4 0 -0.3
F -0.1 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0
I -0.1 0 -0.1 0.3 -0.2 0 0 0 -0.1 0 0 0 0 0.1 0 0 0 -0.1 0 0
L -0.1 0.3 0.2 0.8 0.3 0 0 -0.1 -0.3 -0.2 -0.1 -0.1 -0.1 0 0.3 -0.2 -0.1 -0.3 -0.1 -0.1
V 0 0.3 0.2 -0.2 -0.2 0 0 -0.1 0.1 -0.1 -0.1 0 -0.1 0.1 0 -0.1 -0.1 0 0.4 -0.1
M -0.1 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0
W -0.1 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0 0
Y -0.2 -0.1 -0.1 -0.1 -0.3 0 0 0 -0.1 -0.1 0.4 0 0 0.3 0 0.3 -0.1 0.1 0 -0.1
D 1 -0.2 -0.1 -0.2 0.7 -0.3 -0.1 -0.2 -0.7 -0.1 0.7 0.3 0 0 0.4 -0.1 -0.5 -0.1 0 0.2
E -0.6 0.2 -0.8 -0.1 -0.1 -0.2 -0.1 -0.3 0.2 -0.4 0.5 0.5 -0.3 1.3 0 0.7 0.3 0.7 0 -0.2
K -0.4 -0.2 0.1 0.1 0.3 -0.1 0 -0.1 0.6 0.1 -0.1 -0.1 -0.1 -0.4 -0.1 -0.2 0.5 0.1 -0.1 0.5
R -0.3 0.5 0.2 0.4 0.6 -0.1 0 -0.2 0.2 -0.2 -0.1 -0.1 -0.1 -0.1 -0.1 0.2 -0.3 -0.1 -0.1 0.2
H -0.4 -0.1 0.2 0.1 0 0 0 -0.1 0.1 -0.1 -0.1 -0.1 -0.1 0.1 0 -0.1 -0.1 0 -0.1 0.6
N 1 -0.5 -0.1 0.8 0.4 -0.2 -0.1 0.2 -0.2 -0.4 0.1 -0.2 -0.2 -0.4 -0.2 -0.1 0.3 -0.1 -0.2 0.4
Q -0.6 -0.2 0.5 0.3 0.8 0.3 0 0.5 0.1 0.1 -0.2 0.2 -0.2 0.1 -0.1 -0.3 0 -0.1 -0.1 -0.4
S -0.4 -0.3 0.4 -0.2 0.1 -0.1 0 0.8 -0.4 0.3 -0.2 -0.1 -0.2 -0.1 0 -0.1 0.6 0.6 0.2 -0.1
T 0.3 -0.2 0.2 -0.1 -0.6 -0.1 0 -0.1 1.1 0.1 -0.1 -0.1 0.3 0.2 -0.1 0.2 -0.2 -0.3 0.1 -0.2
G 1.9 1 0.6 -0.2 0.8 0.3 -0.2 0.4 -1.1 -0.6 -0.3 -0.5 0.1 -1 -0.5 -0.1 0.2 -0.1 -0.5 0.3
P 0.2 -0.2 -0.5 -0.3 -0.8 -0.1 0 -0.2 0.6 0.6 -0.2 0.2 0.8 -0.4 0.2 0.7 -0.3 0.2 0.7 -0.4
C -0.2 0 -0.1 0.3 -0.2 0 0 0 -0.1 -0.1 0 0 0.4 -0.1 0 0 0 -0.1 0 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0086 -0.1 -1.1 -0.8 -0.2 -0.4 -1.1 -1.1 -0.6 0.9 1.3 0.3 0.3 -0.5 1 0.4 0.7 0 0.6 0.3 -0.9
0087 1.2 0.3 0.5 0.4 1.6 -1.1 -1.6 -0.4 0.8 -0.1 -0.6 -0.9 -0.6 0.6 -0.8 -0.2 -0.4 1.5 -0.6 0.3
Select residue pair below:
i_j Score Prob
0058_0087 0.668 0.50
Local Interactions:
i_j Score Prob
0086_0087 1.110 0.95
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.021 seconds.