May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [I:0072] and [N:0073]
- A F I L V M W Y D E K R H N Q S T G P C
A 0 -0.1 -0.1 -0.1 -0.1 -0.1 0 0.2 0 0 0 0 -0.2 -0.5 0.6 0 -0.3 0 0.3 0.3
F 0 0 -0.1 -0.1 -0.1 0 0 -0.1 0 0 0 0 -0.3 0.3 -0.1 0.3 0 0 0 -0.1
I 0 -0.1 -0.3 0.5 -0.2 -0.2 0 -0.1 0 0 0 0 -0.2 0.3 0.1 0.6 -0.2 0 0.1 0.2
L 0 -0.1 -0.3 -0.1 -0.1 -0.1 0 -0.2 0 0 0.4 0 0.4 0.8 -0.2 0.1 -0.5 0 -0.1 -0.1
V 0 -0.1 -0.1 0.3 -0.2 -0.1 0 0.2 0 0 0 0 -0.1 0.6 -0.1 0.5 -0.4 0 0.1 -0.1
M 0 0 -0.1 0 -0.1 0 0 0.4 0 0 0 0 0.1 0.2 0 0 -0.4 0 0 0
W 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 -0.1 0 -0.1 -0.1 0 0 0
Y 0 0 -0.1 0 0 0 0 -0.1 0 0 0 0 -0.2 0.3 -0.1 -0.3 0.6 0 -0.1 -0.1
D 0 -0.1 -0.1 -0.1 0.5 0 0 -0.1 0 0 0 0 -0.3 0.7 0 -0.2 -0.1 0 -0.1 -0.1
E -0.1 -0.1 0.3 -0.1 0.2 0.3 0 -0.1 0 0 -0.1 0 0 0.1 -0.2 -0.2 0.3 0.3 -0.1 -0.1
K -0.1 0.4 0.5 -0.3 -0.1 0.4 0 0.8 0 0 -0.1 0 0.3 -0.4 -0.2 -1.1 0.6 -0.1 -0.2 0.1
R 0.2 0.1 -0.3 0.2 -0.2 -0.1 0 -0.1 0 0 0 0 0.3 0.4 0.1 -0.1 -0.1 0 -0.1 -0.1
H -0.1 -0.1 0.2 -0.1 0.2 -0.1 0 -0.1 0 0 0 0 0.6 -0.7 -0.1 0.4 -0.1 0 -0.1 -0.1
N 0 0 -0.1 -0.1 0.9 -0.1 0 -0.1 0 0 0 0 -0.3 -0.6 0 -0.2 0 0 0.2 0.3
Q -0.1 0.5 0.1 0.2 -0.2 0.2 0 0 0 0 0 0 -0.2 -0.2 0.1 -0.2 0.4 -0.1 0.1 -0.1
S 0 0 0.2 0 0 0 0 0 0 0 0 0 0.2 -0.3 0 -0.1 -0.1 0 0 0
T -0.1 -0.2 0.4 -0.1 -0.3 0.1 0 -0.4 0 0 -0.1 0 -0.1 0.1 0 0.8 0.4 -0.1 0.1 0.1
G 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 0.1 0 -0.1 -0.1 0 0 0
P 0.4 0 -0.1 -0.1 0 0 0 -0.1 0 0 0 0 0.2 -0.3 -0.1 -0.1 0.2 0 0 -0.1
C 0 0 0 0 0 0 0 0 0 0 0 0 -0.1 -0.1 0 -0.1 -0.1 0 0 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0072 0.1 -0.6 1.1 0 0.6 -0.1 -0.8 0 -0.4 0.6 0.9 0 0 0.2 0.6 -0.7 0.7 -0.7 -0.3 -0.9
0073 0 0.2 0.2 0.1 0.3 -0.1 -0.4 0.4 -0.4 -0.4 -0.2 -0.4 -0.2 0.3 -0.3 0.3 0.3 -0.2 0.1 0.4
Select residue pair below:
i_j Score Prob
0050_0072 2.675 1.00
0072_0088 1.659 1.00
0072_0089 0.926 0.84
0072_0111 0.681 0.52
0049_0072 0.538 0.30
Local Interactions:
i_j Score Prob
0072_0073 0.699 0.55
0072_0074 0.676 0.51
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0175 seconds.