May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [L:0050] and [D:0111]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.4 0 -0.2 0.6 -0.2 0.1 -0.1 -0.3 0.1 -0.1 0.2 0.5 0.4 -0.3 0.1 -0.6 -0.1 0.1 -0.5 0.8
F -0.1 0 0 0 0 0 0 0 0.2 -0.2 -0.3 -0.2 0 -0.1 -0.1 -0.1 -0.1 -0.1 1.1 0
I -0.2 -0.1 -0.1 0.2 0.5 0.1 0 0.2 -0.1 -0.2 0.7 0.4 -0.3 -0.5 0.4 0.2 -0.5 0.3 -0.1 -0.1
L -0.1 0 0 -0.1 -0.1 0.3 0 0 0.2 0 -0.1 0.7 -0.2 -0.2 0.3 0.2 -0.1 -0.2 -0.1 -0.1
V 0.1 -0.2 0.1 0.2 -0.4 -0.2 -0.1 0.4 0.1 0.2 0.2 0.5 -0.6 0.7 -0.2 0 -0.1 -0.2 -0.1 0.1
M -0.1 0 0 -0.1 0 0 0 0 -0.2 0.1 -0.2 0.3 0 -0.1 0.1 -0.1 0 -0.1 0 0
W -0.1 0 0 0 0 0 0 0 0.5 -0.3 0.1 -0.1 0 -0.1 -0.1 -0.1 0 -0.1 -0.1 0
Y -0.1 0 0 0.3 0 0 0 0 -0.3 -0.4 0.1 0.3 0 -0.1 0.5 -0.1 -0.1 -0.1 -0.1 0
D -0.1 0.7 0 -0.1 0 0 0 0 -0.3 -0.1 0.1 0.1 0 0.5 -0.3 -0.1 0.2 -0.1 -0.1 -0.1
E 0 0 0.4 0 0 0 0 0 -0.2 0 -0.3 -0.1 0 -0.1 -0.1 0.3 0 0 0 0
K -0.1 0 0 -0.1 0 0 0 0 -0.1 0.6 -0.4 -0.2 0 -0.1 -0.2 -0.1 0.3 -0.1 -0.1 0
R 0 0 0 0 0 0 0 0 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 0 0
H 0.3 -0.1 0 -0.4 0.1 -0.1 0 0 -0.4 0.1 0.1 -0.4 0.3 0.3 -0.4 0.4 0.5 0.1 -0.2 -0.1
N -0.1 0 0 -0.1 0 0 0 0 0.3 -0.4 0.5 -0.1 0 -0.1 0.5 -0.1 -0.1 -0.1 -0.1 0
Q 0 0 0 -0.1 0 0 0 0 0.3 0 -0.2 -0.1 0 -0.1 0.2 -0.1 -0.1 -0.1 0 0
S -0.2 0 0 -0.2 -0.1 -0.1 0 0 0.2 0.6 -0.2 -0.1 0.5 0.1 -0.4 0.4 -0.2 0.1 -0.2 -0.1
T 0.3 -0.1 -0.3 -0.8 0.3 0.1 -0.1 -0.1 0.3 0.7 -0.2 -0.2 0.4 0.3 -0.1 -0.5 0.1 1.2 -0.6 -0.5
G -0.1 0 0 0.7 -0.1 0 0 0.2 -0.1 -0.3 -0.2 -0.1 -0.1 -0.2 -0.2 0.4 -0.1 -0.3 0.6 0
P 0.4 -0.3 0 0.1 0.1 -0.3 -0.1 -0.2 0.3 0.3 0 -0.9 -0.1 -0.1 0.2 0 -0.2 0.2 0.7 -0.1
C -0.1 0 0 -0.1 0 0 0 0 -0.1 -0.2 0.1 -0.2 -0.1 0.3 -0.2 0.2 0.7 -0.2 -0.1 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0050 1.1 -0.4 0.9 0.1 1.1 -0.7 -0.7 -0.3 0.1 -0.5 -0.2 -0.9 -0.3 -0.1 -0.6 0.1 1.2 0 1.6 -0.4
0111 0.4 -0.6 -0.7 0 -0.4 -0.4 -1 0.1 1.3 0.4 -0.4 0 0.1 0.6 0.4 0.8 -0.1 0.6 0.1 -0.9
Select residue pair below:
i_j Score Prob
0049_0111 1.052 0.92
0050_0111 0.801 0.70
0072_0111 0.681 0.52
0088_0111 0.638 0.45
0047_0111 0.560 0.33
0042_0111 0.537 0.29
Local Interactions:
i_j Score Prob
0111_0113 0.740 0.61
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0144 seconds.