May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [R:0029] and [E:0173]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.1 -0.1 0.2 -0.1 -0.2 0 0 -0.3 -0.3 0.6 -0.1 0.1 -0.2 0.4 0.1 -0.2 0 0.2 0.1 0.1
F 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0
I 0 0 0 0 0 0 0 0 -0.1 -0.2 0 0 0 0 0 -0.1 0.3 0 0 0
L -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0.3 0 0 -0.1 0 0.2 -0.1 -0.1 0 0
V 0 0 0 0 0 0 0 0 -0.1 0.2 0 0 0 0 0 0 -0.1 0 0 0
M 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0
W 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0
Y 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0
D -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0.3 0 0 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0
E -0.1 0 0 0 0 0 0 0 -0.1 0.1 -0.1 0 0 0 -0.1 -0.1 0.7 -0.1 -0.1 0
K 0.3 -0.2 -0.2 -0.2 0.1 -0.1 -0.1 0.1 0.7 0.6 -0.1 -0.5 -0.3 0.4 0.5 -0.2 -0.3 0.4 -0.1 -0.1
R 0.1 0.3 0.4 0.2 -0.3 -0.1 0 -0.2 0.2 0.3 0.1 -0.1 0.1 -0.2 -0.1 0 0.2 -0.1 0.2 -0.2
H 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0 0
N 0 0 0 0 0 0 0 0 0.3 0.1 -0.1 0 0 0 0 0.1 -0.1 -0.1 0 0
Q -0.1 0 0 0 0 0 0 0 0.6 0.1 -0.1 0 0 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0
S -0.3 -0.2 -0.4 -0.3 0.5 0.3 -0.1 -0.7 0.5 0 -0.2 -0.1 -0.1 0.2 0.5 0.7 0.1 0.1 0 0.1
T -0.1 0 0 0 0 0 0 -0.1 -0.1 -0.3 0.6 0.4 -0.1 -0.1 -0.1 -0.2 -0.1 -0.2 -0.1 0.1
G -0.1 0 0 0 0 0 0 0 -0.2 0.3 -0.1 0 0 0.1 -0.1 -0.1 -0.1 0.3 0 0
P 0.5 -0.1 0 0.4 0.2 -0.5 -0.3 1 -0.4 -0.7 0.2 0.4 0.6 -0.2 -0.3 0.5 -0.4 0.2 0.5 0
C 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0 0 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0029 0.7 -0.9 -0.7 -0.3 -0.7 -0.9 -0.9 -0.9 -0.4 -0.5 2.6 1.6 -0.9 -0.4 -0.3 1.4 0.4 -0.4 2.5 -0.9
0173 0 -0.8 -0.4 -0.5 0.1 -0.9 -1.2 -0.6 1.3 1.9 0.6 -0.2 -0.5 0.3 0.2 0.6 0.1 0.4 -0.2 -0.4
Select residue pair below:
i_j Score Prob
0029_0033 1.427 0.99
0029_0173 1.012 0.90
0012_0029 0.718 0.58
0029_0059 0.663 0.49
Local Interactions:
i_j Score Prob
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.2705 seconds.