May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

DHFR Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [N:0020] and [D:0022]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.5 0 -0.2 -0.1 -0.1 0.2 0 -0.1 -0.1 -0.5 0.1 0.5 0.7 -0.1 -0.1 -0.3 -0.3 0.3 0 -0.1
F 0 0 0 0 0 0 0 0 -0.1 0 -0.1 -0.1 0 0 -0.1 0 -0.1 -0.1 0 0
I 0 0 0 0 0 0 0 0 -0.1 0 -0.1 -0.1 0 0 -0.1 0 -0.1 -0.1 0 0
L -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0.3 -0.1 -0.1 -0.1 -0.1 -0.1 0.2 -0.2 0 0
V 0 0 0 0 0 0 0 0 -0.1 -0.1 0.3 -0.1 0 0 -0.1 -0.1 -0.1 -0.1 0 0
M 0 0 0 0 0 0 0 0 -0.1 0 -0.1 -0.1 0 0 -0.1 0 -0.1 -0.1 0 0
W 0 0 0 0 0 0 0 0 -0.1 0 -0.1 -0.1 0 0 -0.1 0 -0.1 -0.1 0 0
Y 0 0 0 0 0 0 0 0 -0.1 0 -0.1 -0.1 0 0 -0.1 0 -0.1 -0.1 0 0
D 0.3 -0.2 -0.2 0.7 0.6 -0.3 -0.2 0 0.8 0 0.2 -0.2 0.3 -0.2 -0.3 -0.3 0 0.1 -0.2 -0.2
E 0.3 -0.1 -0.2 -0.2 0.1 -0.1 -0.1 -0.1 0.1 -0.1 0.4 0.8 0.4 0.2 -0.3 -0.2 -0.5 0.1 -0.1 -0.1
K -0.5 -0.1 0.5 -0.1 0.1 -0.2 -0.1 -0.1 0.1 0.6 0 0.2 -0.2 0.1 0.4 -0.1 -0.2 -0.1 -0.1 0.3
R 0.4 0 -0.1 -0.1 -0.1 -0.1 0 0 0 0.5 -0.4 0 -0.4 0.3 0.3 -0.2 -0.4 0.7 0 -0.1
H 0.2 0 -0.1 -0.1 -0.1 0 0 0 -0.3 -0.1 -0.4 0.5 0.4 -0.2 -0.1 0.9 0.3 -0.6 0 -0.1
N -0.2 -0.1 0.6 0.1 0 -0.2 -0.1 -0.3 0.3 0.3 -0.1 -0.1 0.1 0.2 0.5 0.2 0.5 -0.1 -0.1 -0.3
Q -0.3 -0.1 -0.2 -0.2 -0.3 -0.1 -0.1 -0.1 -0.6 -0.3 0.5 0.2 0.7 0.3 0.5 0.4 0.2 0.1 -0.1 -0.1
S 0 0 0.3 -0.1 -0.1 0 0 0 -0.3 -0.1 0.1 -0.1 -0.3 -0.1 -0.1 0.1 0.6 0.6 0 -0.1
T -0.1 0 0 0 0 0 0 0 -0.2 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 0.7 -0.2 0.5 0 0
G 0.3 -0.1 -0.3 0 0.2 -0.2 -0.1 -0.1 0.9 0.1 0.2 -0.2 -0.6 0.2 0.4 0.3 0.6 -0.1 -0.1 -0.2
P -0.1 0 0 0 0 0 0 0 -0.1 -0.1 -0.1 -0.1 0.4 0 -0.1 -0.1 -0.1 -0.1 0 0
C -0.1 0 0 0 0 0.4 0 0 -0.1 -0.1 0.1 0 -0.1 -0.1 -0.1 -0.1 0.2 -0.2 0 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0020 0.3 -1.2 -1.2 -0.8 -1 -1.2 -1.2 -1.2 1.2 1 1 0.4 0 1.9 0.5 0.5 -0.5 2 -1 -0.7
0022 0.6 -1.6 -0.6 -0.8 -0.3 -1.3 -1.6 -1.3 1 0.8 1.8 1.2 0.8 0.4 1.2 1 1.6 1.2 -1.6 -1.1
Select residue pair below:
i_j Score Prob
0020_0147 0.553 0.32
Local Interactions:
i_j Score Prob
0019_0020 4.027 1.00
0020_0021 0.987 0.89
0020_0022 0.545 0.31
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...

Page generated in 0.0134 seconds.