May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
DHFR Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix.
Coupling matrix for [Q:0013] and [D:0142]
- A F I L V M W Y D E K R H N Q S T G P C
A 0 -0.1 -0.3 0.6 -0.4 -0.1 -0.1 0.2 0.2 0.3 -0.4 0.2 -0.2 0.4 -0.5 0.7 0.1 -0.3 -0.1 -0.2
F -0.2 0 -0.1 0 -0.1 0 0 0 -0.3 -0.3 0.3 -0.1 -0.1 -0.1 -0.1 -0.2 -0.2 0 0.4 0
I -0.3 0 -0.1 -0.1 0.8 0 0 -0.1 0.5 0.2 -0.2 -0.2 -0.1 0.5 -0.1 -0.3 -0.3 -0.1 -0.1 -0.1
L -0.3 0.2 -0.3 -0.3 0.4 -0.1 -0.1 0.1 -0.3 0 0.2 0.4 0.8 0.1 -0.1 -0.7 0.3 0.1 1 -0.3
V 0 0 -0.2 -0.1 0 0 0 0.5 -0.1 0 -0.3 -0.3 -0.1 0 0.6 0.1 -0.4 0.3 -0.2 0.3
M 0.2 0 -0.1 0.4 -0.1 0 0 0 -0.3 -0.3 -0.1 -0.1 0.4 -0.1 -0.1 -0.2 -0.2 -0.1 0.3 0
W -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0 0 0 -0.1 -0.1 0 0 0
Y 0.8 0 -0.1 -0.1 -0.2 0 0 0 -0.3 0.2 -0.2 0.3 -0.1 0.2 -0.1 -0.2 -0.2 -0.1 -0.1 0
D -0.1 -0.1 0.2 0.2 -0.1 -0.1 -0.1 0.2 0.7 -0.2 -0.2 -0.5 -0.1 0.4 0.5 0.2 0.4 -0.2 -0.3 -0.2
E 0.1 -0.2 -0.6 0 -0.1 0.1 0.2 0.1 -0.3 -0.3 0.7 0.6 0.3 -0.3 0.3 0.5 0.5 -0.5 -0.3 0.4
K 0.3 -0.2 0.6 -0.2 0.4 -0.1 -0.1 -0.2 0.3 1 0.1 -0.7 -0.2 0.4 -0.3 0.4 -0.2 -0.3 -0.3 -0.1
R 0.4 0.2 -0.5 -0.2 0.7 -0.1 -0.1 -0.3 0.7 0.8 0.1 -0.8 -0.2 -0.6 0.1 0.6 0.2 0.1 -0.5 -0.4
H -0.4 -0.1 0.4 -0.1 0.2 0 0 0.3 0.5 -0.2 -0.1 -0.3 0.1 0.1 -0.3 0 -0.2 -0.1 0.2 -0.1
N -0.6 -0.1 0.7 -0.2 -0.1 0 0 -0.1 1 -0.3 0 0 -0.3 0.2 -0.4 0.4 0.4 -0.2 -0.3 0.6
Q 0.1 -0.1 0.1 -0.3 -0.1 -0.1 -0.1 -0.3 -0.6 -0.2 0.7 0.7 -0.2 -0.5 0.1 0.2 1 0.6 -0.4 -0.2
S -0.3 -0.1 -0.2 0.9 -0.2 -0.1 -0.1 -0.2 -0.2 0.1 -0.2 0.4 -0.1 0 0.3 0.1 -0.2 0 -0.3 0.5
T 0.2 -0.1 -0.3 -0.2 0.4 0 0 -0.1 -0.2 0.3 -0.5 -0.1 0 -0.2 -0.3 0 0.4 0.8 0.1 -0.1
G -0.1 -0.1 0.7 0.3 -0.3 0 0 -0.1 -0.1 -0.6 0.3 0.3 -0.3 -0.1 0.2 -0.5 -0.2 -0.1 0.8 -0.1
P 0.3 0.2 -0.2 -0.4 -0.1 -0.1 -0.1 -0.3 -0.6 0.2 0.3 0.7 0 0.1 0.6 -0.3 -0.3 0.2 0.3 -0.3
C -0.1 0 0.3 -0.1 -0.1 0 0 0 0.1 0 -0.1 -0.1 0.2 -0.1 -0.1 -0.2 -0.2 -0.1 -0.1 0
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0013 0.5 -1.1 -0.6 0.7 -0.3 -0.8 -1.6 -0.8 0.3 1.1 0.7 0.7 -0.3 0 0.7 0.4 0.3 0 1.3 -0.8
0142 0.6 -1.4 0.2 -0.5 0.7 -1.7 -1.6 -0.9 1.5 1.3 0.4 0.2 -0.3 0.5 0.2 0.8 1 -0.4 0 -1
Select residue pair below:
i_j Score Prob
0014_0142 1.457 0.99
0013_0142 1.172 0.96
Local Interactions:
i_j Score Prob
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...
Page generated in 0.5526 seconds.