May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
DHFR Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix.
Coupling matrix for [V:0011] and [V:0136]
- A F I L V M W Y D E K R H N Q S T G P C
A -0.5 -0.1 0.3 0.9 -0.1 0.3 0.1 0.5 0 0.2 -0.2 -0.1 0 0 -0.2 0 -0.2 0 0 -0.2
F 0.5 0.2 0.1 -0.7 -0.2 -0.2 0 -0.1 0 0 -0.1 -0.1 -0.1 0 -0.1 0 0.4 0 0 0.3
I -0.2 -0.3 0.6 0.5 0.8 -0.2 -0.1 -0.1 0 -0.1 -0.1 -0.2 -0.1 0 0.2 0 -0.1 0 0 -0.1
L 0.6 -0.2 0.4 0.5 -0.2 -0.2 -0.1 -0.1 0 -0.1 -0.1 -0.2 -0.1 0 -0.1 0 0.3 0 0 -0.1
V 0.1 -0.2 0.2 0.5 0.6 0.8 -0.3 0.1 -0.1 -0.3 0 -0.3 -0.3 -0.1 0 -0.1 -0.3 -0.1 -0.1 0
M -0.3 0.1 0.5 0.9 0.8 -0.1 -0.1 -0.2 0 -0.1 -0.2 -0.5 -0.1 0 -0.2 0 -0.1 0 0 -0.2
W 0 0 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Y 1.2 -0.2 -0.2 -0.4 0.3 -0.2 -0.1 -0.2 0 0 -0.1 -0.2 -0.1 0 -0.1 0 0 0 0 0.3
D 0 0.1 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
E -0.2 -0.2 -0.9 -0.8 -0.1 0.2 -0.1 -0.1 -0.1 -0.2 1.2 1.2 -0.1 -0.1 0.7 -0.1 -0.1 -0.1 -0.1 -0.3
K 0 0 0.2 -0.3 -0.1 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
R 0.2 -0.2 0.6 -0.3 0.1 -0.2 -0.1 -0.1 0 0.6 -0.2 -0.4 -0.1 0 -0.1 0 0 0 0 -0.1
H -0.1 -0.1 0.3 -0.3 -0.1 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0.4 0 0 0
N -0.1 0.7 -0.2 -0.1 -0.2 0 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 0
Q -0.3 -0.3 0 -0.4 0.8 0.2 -0.2 -0.1 -0.1 -0.2 -0.3 0.6 -0.2 -0.1 0.1 -0.1 -0.1 -0.1 -0.1 0.5
S -0.1 -0.1 -0.1 0.2 -0.3 0.5 0.3 0 0 0 -0.1 -0.1 0.3 0 -0.1 0 0 0 0 -0.1
T -0.3 0.3 -0.1 -0.2 -0.5 0.2 0.7 -0.1 0 0.2 -0.2 0 0.4 0 -0.1 0 -0.1 0 0 0.2
G 0 0 0.2 -0.1 -0.1 0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
P 0 0.3 -0.1 -0.2 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
C -0.1 -0.2 -0.3 0.8 0.1 -0.3 -0.1 -0.1 0 0 0.5 0.3 -0.1 0 -0.1 0 -0.1 0 0 -0.1
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0011 0.6 0 0.5 0.5 0.6 0.2 -0.8 -0.1 -0.8 -0.3 -0.5 -0.4 -0.4 -0.5 0.3 0.3 0.4 -0.4 -0.7 0.4
0136 -0.2 0.4 1.8 1.7 1.7 0.7 -0.2 -0.2 -0.9 -0.3 0.1 0.2 -0.3 -0.9 -0.1 -0.9 -0.2 -0.9 -0.9 -0.2
Select residue pair below:
i_j Score Prob
0009_0136 2.296 1.00
0136_0183 1.249 0.98
0011_0136 0.947 0.86
0015_0136 0.815 0.72
Local Interactions:
i_j Score Prob
0134_0136 2.227 1.00
0136_0138 0.831 0.74
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M V G S L ...
Page generated in 0.0135 seconds.