OPENSEQ.org -1516281329- GREMLIN Submission

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Coupling matrix for [A:0295] and [H:0325]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0.3	0.2	-0.3	0.1	-0.5	0	0.6	0.4	-0.1	0.3	0	-0.2	-0.1	-0.1	-0.6	-0.1	-0.4	0.6	-0.1	-0.4
F	0.6	0.2	-0.3	0	0.1	-0.3	-0.4	0.3	-0.1	0.1	0.1	0.1	-0.1	-0.1	0.1	0.5	-0.6	0	-0.1	0.1
I	-0.2	0	0.4	0.5	0.9	0.1	-0.5	-0.5	-0.2	-0.2	-0.3	-0.7	-0.7	0	-0.4	1	0.3	0.3	-0.1	0.1
L	0.1	-0.5	0.9	0.6	0.3	0.6	-0.3	-0.4	0	-0.3	-0.4	-0.4	-0.5	-0.1	0.5	0.5	-0.1	0.3	-0.2	-0.2
V	-0.1	0.4	0.5	0.8	0.1	0.6	-0.4	-0.2	-0.2	0	-0.3	-0.7	-1.5	0.4	0.2	0.2	-0.1	0.6	-0.1	-0.1
M	0.4	0.1	0.3	-0.1	0.1	-0.1	0.1	-0.4	0.2	-0.1	-0.1	-0.2	-0.4	-0.2	0	-0.2	0.1	-0.1	0	0.2
W	0.1	-0.7	-0.2	-0.2	0	-0.1	-0.1	-0.2	0	0	0	-0.1	-0.1	0.2	-0.1	-0.2	0.3	-0.1	0	0.6
Y	0.4	-0.2	0.6	-0.3	0	-0.4	0	0.1	-0.1	0	1.4	0.2	-0.7	-0.3	0.2	-0.3	-0.1	-0.1	-0.1	0.1
D	-0.2	-0.4	-0.4	-0.3	-0.4	-0.1	-0.1	0.6	-0.2	-0.2	-0.3	1.2	0.5	-0.2	-0.2	-0.6	1.2	-0.1	-0.1	0.6
E	0.2	0	-0.1	-0.3	0	-0.1	0.3	0.4	0	0.7	-0.1	1.4	0.4	-0.2	-0.3	-0.5	-0.6	-0.5	-0.1	-0.4
K	-0.7	-0.4	0.1	-0.2	0.2	-0.2	0.2	0.5	0.3	-0.2	-0.2	-0.6	-0.1	0.1	0.6	-0.2	0.3	0	-0.1	0.4
R	0.8	0.3	-0.3	0.2	0.3	-0.6	0	-0.5	0.2	0.1	-0.3	-0.3	0.6	-0.3	-0.5	0	0.1	-0.1	0.3	0.7
H	0.1	-0.5	-0.6	-0.1	-0.2	-0.1	0.4	-0.1	-0.1	0.1	0.4	0.7	0.1	-0.1	0.2	0.3	-0.3	0	-0.1	0.3
N	-0.5	0.1	0.1	-0.3	-0.1	0.1	0.4	0.3	-0.1	-0.1	-0.2	0.1	0.5	0.1	-0.1	-0.5	-0.1	-0.3	-0.1	-0.4
Q	-0.3	0.4	-0.3	-0.3	-0.2	-0.3	0.8	0.3	-0.1	0.1	0.1	-0.4	0.2	-0.1	-0.3	0.2	0.2	0	0.2	-0.2
S	-0.7	0.3	0.4	-0.3	0.1	-0.1	0	0.4	0.2	0.2	0.1	-0.1	0.9	0.3	0	-0.3	-0.3	0	0	-0.5
T	0	0.5	-0.2	0.1	0.2	0	0	0.5	0.2	-0.1	-0.3	0.1	0.2	-0.5	0.2	-0.1	0.1	-0.3	-0.1	0
G	0.2	0.2	-0.2	0.1	-0.5	0.1	0.8	0.4	-0.2	-0.6	-0.4	0	0.7	0.1	0	-0.1	-0.5	0.1	0.2	0
P	0	0.3	-0.2	0.1	-0.2	0.5	0.3	-0.7	0	-0.2	0	0.2	0.3	0.5	0.5	0.2	0.1	-0.5	-0.2	-0.3
C	-0.4	1	0.2	0.6	-0.1	0	0	0.4	-0.1	-0.1	-0.1	-0.5	-0.2	0	-0.3	-0.1	0	-0.2	-0.1	-0.1

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0295	0.4	-0.4	0.2	0.4	0.4	-0.9	-2	-0.7	0.5	0.6	0.3	0.5	0	-0.2	-0.4	0.6	0.6	0.7	0.5	-0.7
0325	0.3	1.1	0.9	1.1	0.6	-0.1	2.5	1.6	-0.9	-0.9	-1.2	-0.2	0.3	-0.5	-0.2	-0.3	-0.2	-0.5	-1.2	0.4

Select residue pair below:

i_j	Score	Prob
0296_0325	0.878	0.84
0295_0325	0.810	0.77
0314_0325	0.787	0.74
0315_0325	0.758	0.70

Local Interactions:

i_j	Score	Prob
0323_0325	0.901	0.86
0325_0326	0.705	0.61
0325_0327	0.615	0.46
0324_0325	0.549	0.35

See all coupling residues
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