OPENSEQ.org -1516281329- GREMLIN Submission

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mep50

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Coupling matrix for [F:0072] and [S:0074]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0.1	0.2	-0.1	0.2	-0.2	-0.1	-0.3	-0.1	0.3	0.3	0.2	0	0.1	-0.1	0.1	0.3	0.1	-0.6	-0.2	0.1
F	0.5	-0.2	-0.6	-0.1	-0.1	-0.1	-0.4	0.1	0	0.3	0	-0.3	-0.5	0.5	-0.5	0.3	0.1	1	0.3	0
I	-0.2	-0.4	-0.5	-0.7	-0.5	-0.6	-0.1	-0.4	0.1	0	0.7	0.2	0.2	0.4	0.2	0.5	0.2	0.3	0.9	-0.4
L	-0.1	-0.3	-0.3	0	-0.2	-0.2	-0.3	-0.8	0.2	0.3	0.5	0	-0.1	0.1	0.6	0.1	0.3	0.5	0.4	-0.7
V	0.2	-0.5	-0.6	-0.6	-0.5	-0.2	0.6	-0.7	0.1	0.1	0.4	-0.2	0.3	0.4	0.2	0.5	0.2	0.4	0.6	-0.5
M	-0.3	0	-0.4	-0.5	-0.3	-0.2	0.6	0.1	0.3	0.1	0.1	0.1	0.1	0	-0.2	-0.3	-0.1	-0.3	0.7	-0.3
W	0	-0.1	-0.2	-0.5	-0.3	0.1	0.1	-0.2	-0.2	0.2	-0.1	-0.2	-0.2	0	0.1	-0.1	-0.1	1	0	0.2
Y	-0.1	-0.2	-0.4	0.5	0	0.9	-0.2	-0.1	-0.2	0.2	-0.1	-0.8	-0.2	0.6	-0.6	0.4	0.5	-0.5	0	0.2
D	0.2	-0.1	0.2	-0.1	0.5	-0.4	-0.4	-0.1	0.5	-0.1	0.3	0.5	-0.1	0.1	0.1	-0.4	0.1	0.2	-0.3	-0.5
E	1.1	-0.1	0.2	0.6	0.3	0	-0.1	0	-1.1	-0.2	0	0.1	-0.1	-0.1	-0.3	0.6	-0.4	0.3	-0.5	0.3
K	-0.2	0.3	0.4	0.4	0.1	0.3	-0.7	0.3	0.2	-0.4	-0.2	0.1	-0.2	-0.1	-0.1	0.1	0.3	0	-0.2	-0.1
R	-0.5	0.7	0.4	0.4	0.3	0.3	-0.3	-0.1	0.7	-0.2	-0.1	0.9	-0.1	-0.6	-0.3	-0.5	-0.2	-0.7	-0.5	0.3
H	0.1	-0.1	-0.1	0.1	0.2	-0.1	-0.1	0.1	-0.1	0	-0.9	0.1	0.1	-0.2	0.6	-0.1	-0.6	-0.6	-0.6	0.8
N	-0.5	0.3	0.9	0.2	0	-0.6	-0.2	-0.3	0.5	0.2	-0.3	0.2	0	0.3	0.1	-0.1	0.1	0	-0.3	-0.4
Q	0.2	0.3	0.4	0.2	0.2	-0.3	0.5	0.4	0.1	-0.3	-0.2	-0.3	0.1	-0.2	0.5	-0.4	0.2	-0.5	0	-0.3
S	0.4	0.1	0.2	-0.1	0.1	-0.1	0	0.5	0	-0.2	-0.4	-0.3	-0.2	-0.3	0.3	0.4	-0.1	-0.1	-0.1	0.4
T	0	0.1	0.3	0.3	0.1	0.4	0.6	0.2	-0.4	-0.3	0	-0.3	0.5	0	-0.1	-0.1	-0.1	-0.6	0.1	-0.3
G	-0.2	0.2	-0.2	0.1	0.3	-0.3	0	0.1	-0.4	-0.1	0.2	0.7	-0.1	-0.2	-0.3	0.3	-0.5	0.1	-0.4	0.2
P	-0.4	0.1	0.9	0.2	0.5	0.1	0.2	0.8	-0.6	-0.4	-0.3	0.3	0.1	-0.7	-0.8	-0.3	-0.3	0	0.3	0.2
C	0	-0.3	-0.3	0.3	0.2	0.5	-0.2	-0.1	-0.1	0	-0.2	-0.5	-0.4	-0.2	-0.2	-0.3	0.7	-0.2	-0.2	0.6

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0072	0.2	0.4	0	0.7	0.3	-1	-2	-0.5	-0.2	0.7	0.8	0.5	-0.5	-0.2	0.3	0.5	0.4	-0.8	-0.1	-1.2
0074	0.3	-0.1	0.7	1.7	0.9	-0.6	-1.6	-0.8	-0.2	0.2	0.4	0.4	-0.5	-0.4	0	0.6	0.4	-0.6	-0.3	-1.1

Select residue pair below:

i_j

Score

Prob

Local Interactions:

i_j	Score	Prob
0074_0076	1.496	1.00
0074_0075	1.002	0.92
0072_0074	0.590	0.42

See all coupling residues
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