OPENSEQ.org -1515484907- GREMLIN Submission

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PRMT5 1-300

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Coupling matrix for [I:0218] and [L:0253]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0	-0.1	-0.1	0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
F	0	-0.2	0.3	-0.1	-0.1	-0.1	0.5	0	0	0	0	0	0	0	0	0	0	0	0	0
I	0.4	-0.4	0.8	0.2	0.4	0.8	-0.2	0	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.3	-0.1	-0.1	-0.1
L	0	1.4	-0.1	0.6	0.7	-0.7	-0.2	0	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.2	-0.1	-0.1	-0.1
V	-0.2	-0.4	1	0.2	0.8	0	-0.1	-0.1	0	0	0	0	0	0	0	0	-0.1	0	0	0
M	0	-0.2	0.3	0.8	-0.1	-0.2	0	0	0	0	0	0	0	0	0	0	0	0	0	0
W	0	0.2	-0.1	0.1	-0.1	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Y	0	0.1	-0.1	0.5	-0.1	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0
D	0	-0.1	0	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
E	0	-0.1	0	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
K	0	-0.1	0	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
R	0	-0.1	0	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
H	0	-0.1	0	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
N	0	-0.1	0	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Q	-0.1	0.6	-0.8	0.4	-0.4	1	-0.1	0.3	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1
S	0	-0.2	-0.1	-0.4	-0.1	0	0	0	0	0	0	0	0	0	0	0	0.9	0	0	0
T	0	0.4	-0.1	-0.3	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
G	0	-0.1	0	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
P	0	-0.1	0	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
C	0	0.3	-0.1	-0.2	-0.1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0218	-0.3	0.1	1.3	2	1.3	0.6	0	0	-0.5	-0.5	-0.5	-0.5	-0.5	-0.5	-0.1	0	-0.2	-0.5	-0.5	-0.3
0253	-0.1	1.5	1.2	1.4	0.8	0.8	-0.2	0.2	-0.5	-0.5	-0.5	-0.5	-0.5	-0.5	-0.5	-0.5	-0.1	-0.5	-0.5	-0.5

Select residue pair below:

i_j	Score	Prob
0253_0257	1.963	0.98
0208_0253	1.932	0.97
0218_0253	1.688	0.93
0235_0253	0.881	0.33
0187_0253	0.794	0.25

Local Interactions:

i_j

Score

Prob

See all coupling residues
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