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PRMT5 1-300 Return to Main Page
Instructions
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Coupling matrix for [A:0205] and [I:0230]
- A F I L V M W Y D E K R H N Q S T G P C
A -0.9 -0.3 1.4 0 0.7 -0.5 0.2 0.3 -0.2 -0.1 -0.2 -0.4 0.2 -0.1 -0.5 -0.3 1.5 -0.2 -0.2 0.4
F 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
I 0 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 0.9 0.2 -0.1 0 0 -0.1
L 1.3 0 -0.1 -0.1 -0.4 -0.1 -0.1 -0.1 0 -0.1 0 0 0.4 -0.1 0 0.1 -0.2 0 0 -0.1
V 0 -0.2 0.9 0.1 0.5 0.5 -0.4 0.2 -0.1 -0.1 -0.1 0.4 -0.2 -0.1 -0.1 0.1 -0.4 -0.1 -0.1 -0.2
M -0.1 -0.1 -0.2 -0.3 0.2 -0.1 -0.1 -0.1 0 0.5 0 0 0 0.5 0 0.2 -0.2 0 0 -0.1
W 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Y 0.5 -0.1 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 -0.1 0 0 0 0
D 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
E 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
K 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
R 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
H 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
N 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Q 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
S -0.2 0.2 0 1.3 0 0.2 -0.3 -0.1 0 -0.1 0 -0.1 -0.1 -0.1 -0.1 0.3 -0.2 0 0 -0.1
T -0.1 1.1 -0.5 0.4 -0.1 -0.1 0.6 0.1 0 -0.1 0 -0.1 -0.1 -0.1 -0.1 -0.3 -0.2 0 0 -0.2
G -0.1 0.1 -0.1 -0.4 -0.3 -0.2 0.5 -0.1 0 -0.1 0 -0.1 -0.1 -0.1 -0.1 0.8 0 0 0 0.9
P 0 -0.1 -0.1 0.3 -0.1 0 -0.1 0 0 0 0 0 0 0 0 -0.1 0.4 0 0 0
C -0.1 0.4 -0.4 0 0.5 0.7 -0.1 -0.1 0 0 0 0 -0.1 0 0 -0.2 -0.1 0 0 -0.1
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0205 1.6 -0.6 0.2 0.5 0.7 0.2 -0.6 -0.3 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 -0.6 0.9 0.5 0.9 -0.1 0.2
0230 0 0.6 0.4 0.6 0.9 0.3 0 0 -0.7 -0.4 -0.7 -0.5 -0.2 -0.3 -0.2 0.9 0.7 -0.7 -0.7 0.3
Select residue pair below:
i_j Score Prob
0084_0119 4.060 1.00
0226_0257 3.188 1.00
0286_0290 2.219 0.99
0239_0283 2.104 0.99
0142_0202 2.016 0.98
0253_0257 1.963 0.98
0208_0253 1.932 0.97
0239_0251 1.781 0.95
0248_0251 1.755 0.95
0213_0250 1.754 0.95
0245_0251 1.700 0.93
0078_0082 1.689 0.93
0218_0253 1.688 0.93
0229_0257 1.594 0.90
0125_0154 1.572 0.89
0189_0225 1.570 0.89
0127_0134 1.557 0.89
0212_0250 1.548 0.88
0070_0073 1.535 0.88
0092_0123 1.523 0.87
0151_0265 1.484 0.85
0152_0263 1.465 0.84
0084_0122 1.459 0.84
0033_0041 1.448 0.83
0125_0134 1.440 0.83
0047_0052 1.419 0.82
0237_0247 1.398 0.80
0073_0080 1.388 0.80
0089_0106 1.388 0.80
0089_0103 1.376 0.79
0170_0173 1.368 0.78
0190_0193 1.364 0.78
0272_0282 1.357 0.78
0243_0287 1.347 0.77
0239_0244 1.345 0.77
0083_0121 1.329 0.75
0295_0298 1.328 0.75
0090_0103 1.328 0.75
0276_0279 1.323 0.75
0266_0284 1.321 0.75
0155_0203 1.314 0.74
0121_0152 1.292 0.72
0038_0147 1.291 0.72
0239_0245 1.287 0.72
0212_0249 1.282 0.72
0205_0230 1.280 0.71
0087_0090 1.276 0.71
0082_0184 1.273 0.71
0037_0204 1.273 0.71
0221_0224 1.271 0.71
0082_0296 1.259 0.70
0066_0109 1.249 0.69
0045_0113 1.247 0.69
0251_0283 1.243 0.68
0142_0196 1.239 0.68
0107_0210 1.238 0.68
0109_0117 1.232 0.67
0126_0134 1.228 0.67
0203_0227 1.227 0.67
0104_0136 1.219 0.66
0038_0245 1.214 0.66
0196_0202 1.209 0.65
0265_0284 1.205 0.65
0076_0298 1.203 0.65
0244_0283 1.201 0.64
0226_0240 1.201 0.64
0095_0266 1.200 0.64
0246_0251 1.190 0.63
0185_0188 1.187 0.63
0074_0113 1.181 0.62
0111_0151 1.179 0.62
0099_0284 1.169 0.61
0050_0054 1.169 0.61
0100_0104 1.156 0.60
0241_0245 1.154 0.60
0018_0022 1.150 0.59
0245_0283 1.150 0.59
0155_0206 1.145 0.59
0187_0222 1.142 0.59
0264_0284 1.140 0.58
0067_0070 1.139 0.58
0093_0267 1.136 0.58
0019_0085 1.133 0.58
0067_0157 1.132 0.58
0125_0212 1.129 0.57
0094_0103 1.128 0.57
0133_0223 1.127 0.57
0186_0189 1.124 0.57
0070_0250 1.113 0.56
0047_0068 1.106 0.55
0239_0243 1.105 0.55
0297_0300 1.103 0.55
0057_0061 1.099 0.54
0233_0268 1.093 0.54
0232_0280 1.092 0.54
0018_0157 1.087 0.53
0222_0293 1.082 0.53
0087_0186 1.080 0.52
0208_0229 1.076 0.52
0063_0138 1.076 0.52
0246_0283 1.073 0.52
0247_0250 1.069 0.51
0076_0079 1.068 0.51
0050_0097 1.067 0.51
0184_0220 1.067 0.51
0272_0275 1.066 0.51
0136_0201 1.064 0.51
0193_0198 1.062 0.50
0040_0250 1.061 0.50
0093_0104 1.058 0.50
0149_0155 1.055 0.50
0242_0282 1.054 0.50
0038_0234 1.052 0.49
0082_0093 1.047 0.49
0043_0086 1.041 0.48
0107_0111 1.041 0.48
0119_0166 1.040 0.48
0189_0193 1.038 0.48
0131_0229 1.033 0.47
0187_0290 1.026 0.47
0247_0277 1.022 0.46
0106_0138 1.021 0.46
0094_0146 1.019 0.46
0110_0113 1.018 0.46
0160_0209 1.018 0.46
0124_0134 1.017 0.46
0147_0150 1.017 0.46
0208_0284 1.016 0.46
0058_0061 1.015 0.46
0094_0099 1.009 0.45
0094_0156 1.007 0.45
0097_0104 1.007 0.45
0013_0021 1.005 0.45
0167_0170 1.004 0.44
0170_0174 1.004 0.44
0073_0078 1.003 0.44
0078_0093 1.003 0.44
0175_0178 1.002 0.44
0233_0297 1.002 0.44
0214_0290 0.999 0.44
0243_0283 0.999 0.44
0106_0265 0.999 0.44
0282_0286 0.998 0.44
0194_0198 0.998 0.44
0056_0204 0.992 0.43
0272_0280 0.991 0.43
0204_0249 0.991 0.43
0018_0021 0.989 0.43
0065_0204 0.987 0.43
0134_0141 0.987 0.43
0117_0228 0.986 0.43
0053_0075 0.983 0.42
0070_0193 0.983 0.42
0243_0272 0.979 0.42
0230_0280 0.979 0.42
0107_0153 0.974 0.41
0156_0273 0.974 0.41
0248_0258 0.974 0.41
0042_0050 0.973 0.41
0113_0198 0.973 0.41
0083_0200 0.971 0.41
0075_0116 0.971 0.41
0171_0175 0.969 0.41
0019_0042 0.969 0.41
0231_0276 0.967 0.41
0241_0282 0.965 0.41
0122_0293 0.964 0.40
0223_0277 0.963 0.40
0103_0181 0.962 0.40
0113_0116 0.959 0.40
0134_0202 0.959 0.40
0041_0135 0.957 0.40
0164_0167 0.956 0.40
0167_0174 0.956 0.40
0084_0087 0.955 0.40
0048_0084 0.954 0.39
0241_0247 0.953 0.39
0117_0237 0.952 0.39
0132_0158 0.951 0.39
0211_0238 0.951 0.39
0174_0177 0.950 0.39
0090_0298 0.949 0.39
0232_0267 0.949 0.39
0189_0224 0.949 0.39
0122_0199 0.948 0.39
0014_0019 0.945 0.39
0175_0179 0.944 0.38
0031_0035 0.943 0.38
0087_0100 0.943 0.38
0254_0258 0.940 0.38
0075_0209 0.939 0.38
0198_0202 0.939 0.38
0186_0224 0.939 0.38
0017_0242 0.937 0.38
0097_0197 0.935 0.38
0131_0191 0.934 0.37
0239_0248 0.930 0.37
0153_0180 0.928 0.37
0040_0152 0.928 0.37
0039_0196 0.927 0.37
0072_0223 0.926 0.37
0140_0210 0.924 0.37
0048_0287 0.924 0.37
0029_0235 0.924 0.37
0167_0278 0.924 0.37
0091_0106 0.923 0.36
0065_0081 0.923 0.36
0083_0152 0.922 0.36
0093_0100 0.922 0.36
0227_0263 0.920 0.36
0191_0234 0.917 0.36
0222_0284 0.917 0.36
0048_0070 0.915 0.36
0208_0226 0.912 0.35
0096_0202 0.912 0.35
0045_0235 0.911 0.35
0243_0251 0.911 0.35
0208_0295 0.911 0.35
0241_0244 0.910 0.35
0044_0193 0.910 0.35
0118_0258 0.909 0.35
0110_0239 0.909 0.35
0274_0284 0.908 0.35
0203_0248 0.906 0.35
0226_0269 0.906 0.35
0187_0226 0.906 0.35
0111_0122 0.906 0.35
0119_0122 0.905 0.35
0186_0193 0.905 0.35
0179_0182 0.905 0.35
0108_0157 0.904 0.35
0127_0155 0.903 0.35
0130_0161 0.900 0.34
0124_0153 0.899 0.34
0083_0156 0.898 0.34
0181_0214 0.897 0.34
0235_0287 0.896 0.34
0033_0284 0.896 0.34
0127_0192 0.896 0.34
0122_0151 0.895 0.34
0239_0246 0.895 0.34
0087_0093 0.894 0.34
0167_0175 0.894 0.34
0076_0286 0.893 0.34
0022_0089 0.893 0.34
0108_0231 0.892 0.34
0033_0112 0.888 0.33
0090_0110 0.887 0.33
0147_0193 0.887 0.33
0108_0111 0.887 0.33
0215_0256 0.886 0.33
0046_0066 0.886 0.33
0024_0284 0.885 0.33
0169_0176 0.884 0.33
0103_0110 0.883 0.33
0057_0062 0.883 0.33
0052_0068 0.883 0.33
0026_0107 0.882 0.33
0235_0253 0.881 0.33
0038_0208 0.881 0.33
0017_0040 0.880 0.32
0211_0235 0.879 0.32
0272_0276 0.878 0.32
0179_0183 0.878 0.32
0015_0019 0.878 0.32
0095_0099 0.878 0.32
0042_0268 0.877 0.32
0235_0285 0.876 0.32
0126_0218 0.876 0.32
0194_0217 0.876 0.32
0020_0041 0.875 0.32
0047_0072 0.874 0.32
0171_0174 0.874 0.32
0167_0172 0.874 0.32
0045_0197 0.872 0.32
0041_0094 0.870 0.32
0155_0230 0.870 0.32
0173_0176 0.869 0.31
0094_0220 0.869 0.31
0054_0102 0.869 0.31
0030_0069 0.869 0.31
0085_0123 0.867 0.31
0103_0265 0.866 0.31
0011_0014 0.865 0.31
0127_0202 0.864 0.31
0176_0208 0.864 0.31
0165_0264 0.863 0.31
0179_0279 0.863 0.31
0166_0170 0.861 0.31
0104_0133 0.860 0.31
0092_0137 0.859 0.31
0244_0251 0.858 0.30
0138_0284 0.858 0.30
0028_0235 0.856 0.30
0186_0221 0.856 0.30
0125_0207 0.854 0.30
0123_0185 0.853 0.30
0095_0204 0.852 0.30
0093_0139 0.851 0.30
0176_0179 0.851 0.30
0276_0282 0.851 0.30
0044_0218 0.849 0.30
0079_0082 0.848 0.30
0152_0228 0.846 0.29
0065_0138 0.846 0.29
0129_0235 0.846 0.29
0152_0203 0.845 0.29
0180_0184 0.845 0.29
0125_0213 0.844 0.29
0170_0175 0.843 0.29
0153_0202 0.843 0.29
0113_0292 0.843 0.29
0167_0171 0.842 0.29
0078_0211 0.842 0.29
0025_0034 0.841 0.29
0118_0229 0.841 0.29
0048_0052 0.840 0.29
0189_0283 0.839 0.29
0152_0205 0.838 0.29
0143_0297 0.838 0.29
0060_0106 0.837 0.29
0059_0254 0.837 0.29
0153_0197 0.836 0.29
0073_0135 0.836 0.29
0092_0127 0.836 0.29
0144_0153 0.834 0.28
0082_0286 0.834 0.28
0107_0123 0.833 0.28
0070_0078 0.833 0.28
0014_0018 0.833 0.28
0117_0137 0.833 0.28
0084_0094 0.832 0.28
0093_0272 0.831 0.28
0174_0178 0.830 0.28
0128_0249 0.830 0.28
0185_0217 0.829 0.28
0084_0271 0.829 0.28
0130_0188 0.829 0.28
0215_0241 0.828 0.28
0221_0225 0.828 0.28
0082_0085 0.827 0.28
0077_0192 0.827 0.28
0114_0244 0.827 0.28
0211_0250 0.826 0.28
0189_0221 0.824 0.28
0029_0260 0.823 0.27
0178_0182 0.823 0.27
0194_0284 0.823 0.27
0184_0288 0.823 0.27
0223_0263 0.822 0.27
0096_0142 0.822 0.27
0041_0130 0.821 0.27
0073_0094 0.821 0.27
0205_0213 0.820 0.27
0084_0174 0.820 0.27
0118_0288 0.818 0.27
0177_0182 0.818 0.27
0115_0288 0.818 0.27
0067_0073 0.818 0.27
0075_0185 0.818 0.27
0110_0221 0.816 0.27
0072_0232 0.816 0.27
0045_0142 0.816 0.27
0151_0167 0.816 0.27
0260_0267 0.815 0.27
0026_0043 0.814 0.27
0013_0019 0.814 0.27
0139_0258 0.813 0.27
0115_0291 0.812 0.27
0065_0254 0.806 0.26
0114_0239 0.806 0.26
0168_0175 0.806 0.26
0020_0105 0.806 0.26
0027_0099 0.806 0.26
0090_0157 0.805 0.26
0011_0021 0.805 0.26
0231_0235 0.805 0.26
0146_0231 0.804 0.26
0208_0273 0.804 0.26
0076_0295 0.803 0.26
0190_0300 0.803 0.26
0066_0107 0.802 0.26
0172_0296 0.801 0.26
0112_0135 0.800 0.26
0218_0266 0.800 0.26
0089_0094 0.800 0.26
0033_0052 0.798 0.25
0051_0212 0.798 0.25
0177_0181 0.798 0.25
0169_0172 0.797 0.25
0171_0176 0.795 0.25
0056_0111 0.795 0.25
0254_0268 0.795 0.25
0137_0140 0.794 0.25
0193_0201 0.794 0.25
0152_0206 0.794 0.25
0120_0300 0.794 0.25
0187_0253 0.794 0.25
0102_0207 0.794 0.25
0012_0291 0.793 0.25
0208_0231 0.793 0.25
0155_0164 0.793 0.25
0152_0248 0.792 0.25
0066_0104 0.792 0.25
0088_0232 0.792 0.25
0107_0110 0.791 0.25
0168_0172 0.791 0.25
0292_0296 0.791 0.25
0073_0112 0.790 0.25
0182_0202 0.790 0.25
0241_0286 0.790 0.25
0093_0280 0.788 0.25
0063_0075 0.788 0.25
0025_0113 0.787 0.25
0268_0271 0.787 0.25
0091_0198 0.786 0.25
0100_0109 0.786 0.25
0077_0229 0.786 0.25
0151_0247 0.786 0.25
0136_0213 0.785 0.24
0113_0192 0.785 0.24
0054_0075 0.785 0.24
0133_0136 0.784 0.24
0103_0106 0.783 0.24
0094_0213 0.783 0.24
0038_0072 0.783 0.24
0169_0274 0.783 0.24
0238_0250 0.783 0.24
0041_0095 0.781 0.24
0089_0110 0.781 0.24
0067_0204 0.781 0.24
0063_0106 0.781 0.24
0175_0254 0.780 0.24
0217_0241 0.779 0.24
Local Interactions:
i_j Score Prob
0212_0213 2.591 1.00
0174_0175 1.788 0.95
0172_0173 1.750 0.95
0166_0167 1.655 0.92
0126_0127 1.544 0.88
0177_0178 1.536 0.88
0167_0168 1.442 0.83
0060_0061 1.435 0.83
0171_0173 1.428 0.82
0173_0174 1.414 0.81
0171_0172 1.384 0.79
0014_0015 1.352 0.77
0241_0243 1.298 0.73
0120_0121 1.286 0.72
0204_0205 1.270 0.71
0058_0060 1.264 0.70
0087_0089 1.262 0.70
0243_0244 1.245 0.68
0162_0163 1.199 0.64
0053_0054 1.199 0.64
0175_0177 1.194 0.64
0242_0244 1.183 0.63
0176_0177 1.174 0.62
0198_0199 1.151 0.60
0097_0098 1.146 0.59
0170_0172 1.144 0.59
0173_0175 1.129 0.57
0245_0246 1.128 0.57
0011_0012 1.123 0.57
0019_0020 1.086 0.53
0089_0090 1.085 0.53
0168_0169 1.085 0.53
0091_0092 1.081 0.52
0165_0167 1.052 0.49
0165_0166 1.049 0.49
0168_0170 1.041 0.48
0175_0176 1.027 0.47
0199_0201 1.022 0.46
0164_0166 1.018 0.46
0013_0015 1.014 0.45
0096_0098 1.014 0.45
0016_0018 1.008 0.45
0234_0235 1.001 0.44
0174_0176 1.000 0.44
0163_0164 0.999 0.44
0183_0184 0.986 0.43
0023_0024 0.983 0.42
0182_0183 0.979 0.42
0069_0071 0.975 0.42
0186_0188 0.962 0.40
0015_0016 0.952 0.39
0020_0021 0.930 0.37
0170_0171 0.922 0.36
0241_0242 0.919 0.36
0017_0018 0.909 0.35
0169_0171 0.906 0.35
0226_0227 0.898 0.34
0012_0013 0.891 0.33
0100_0102 0.891 0.33
0162_0164 0.884 0.33
0021_0023 0.877 0.32
0293_0295 0.875 0.32
0178_0180 0.869 0.31
0182_0184 0.869 0.31
0296_0297 0.866 0.31
0013_0014 0.859 0.31
0237_0238 0.858 0.30
0065_0067 0.857 0.30
0172_0174 0.857 0.30
0298_0299 0.856 0.30
0240_0241 0.853 0.30
0299_0300 0.849 0.30
0298_0300 0.846 0.29
0058_0059 0.845 0.29
0023_0025 0.840 0.29
0274_0275 0.840 0.29
0014_0016 0.827 0.28
0179_0180 0.825 0.28
0056_0057 0.816 0.27
0026_0027 0.815 0.27
0094_0095 0.815 0.27
0025_0027 0.812 0.27
0259_0260 0.802 0.26
0169_0170 0.797 0.25
0160_0162 0.797 0.25
0275_0276 0.791 0.25
0230_0232 0.790 0.25
0179_0181 0.783 0.24
0176_0178 0.783 0.24
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M A A M A ...
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