OPENSEQ.org -1515484907- GREMLIN Submission

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PRMT5 1-300

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Coupling matrix for [T:0176] and [E:0177]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0.3	-0.1	0	0.2	-0.3	-0.2	-0.1	0.6	0	0.1	-0.1	-0.3	-0.1	0	0	-0.1	0	-0.3	0.8	0.1
F	0	0	0	0	0	0	0	0	-0.1	-0.1	0	0	0	0	0	-0.1	0	0	0	0
I	-0.1	0	-0.1	0.2	-0.1	-0.1	0	0	0.3	-0.2	-0.1	-0.1	0	-0.1	-0.1	0.2	-0.1	0.3	-0.1	-0.1
L	-0.2	0.4	0.3	-0.1	0.1	0.3	0	-0.1	0	0.2	-0.1	-0.1	0	-0.1	-0.2	0.2	-0.1	-0.2	-0.1	-0.1
V	0.3	-0.1	-0.2	-0.1	-0.1	-0.1	0	-0.1	0	0	0.3	-0.1	0	-0.1	-0.1	1.1	-0.1	-0.2	-0.2	-0.1
M	0.3	0	0	0	0	0	0	0	0.1	-0.1	0	0	0	0	-0.1	-0.1	0	-0.1	0	0
W	0.3	0	0	0	0	0	0	0	-0.1	-0.1	0	0	0	-0.1	0	-0.1	0	0	0	0
Y	0	0	0	0	0	0	0	0	-0.1	-0.1	0	0	0	0	0	-0.1	0	0	0	0
D	-0.5	0.1	0.5	0.4	0	-0.2	-0.1	-0.1	0.3	0.2	0.1	-0.2	-0.1	0.3	0	0.2	-0.2	0	0	-0.2
E	-0.5	-0.2	0.3	0.3	0.2	0.2	-0.1	0.1	0.6	0.6	-0.2	0	-0.1	-0.1	0	-0.3	-0.2	0.2	-0.2	0.2
K	0.7	-0.1	-0.1	-0.2	0.2	-0.1	0	-0.1	-0.1	-0.2	-0.1	0.2	-0.1	0.2	-0.2	0.2	0.1	0.1	-0.2	-0.1
R	0.8	-0.1	-0.1	-0.1	0.2	0.3	0	0	-0.3	-0.3	-0.1	0.3	0	-0.1	-0.1	-0.2	-0.2	0	0.3	-0.1
H	0.2	0	-0.1	0.4	-0.1	0	0	0	-0.1	-0.1	-0.1	-0.1	0	-0.1	-0.1	-0.2	0.4	-0.2	-0.1	0
N	-0.4	0.3	-0.2	-0.2	0.1	0.3	0	-0.1	0.8	-0.3	-0.2	0.2	-0.1	0.5	-0.2	0.4	-0.2	0.1	-0.3	-0.1
Q	-0.4	-0.1	-0.2	-0.1	-0.3	-0.1	0	-0.1	-0.1	0.2	0.2	-0.1	-0.1	0.1	1.4	0.1	0	-0.3	0.3	-0.1
S	0.2	-0.1	-0.2	-0.2	-0.2	-0.1	0	-0.1	0.3	0.4	-0.2	0.1	-0.1	-0.2	0.1	-0.1	0.5	0.3	-0.2	0.2
T	0.1	-0.1	-0.2	0.1	0	-0.1	0	-0.1	0	0.5	0	0.2	-0.1	0.5	-0.3	-0.5	-0.2	0.1	0.4	-0.1
G	-0.4	-0.1	-0.2	-0.2	0.1	-0.1	0	-0.1	-0.7	0.4	0.1	0	0.4	0	0	0	0.3	0.7	0	0.1
P	-0.4	-0.1	0.5	0.1	0.2	-0.1	0	-0.1	0	-0.1	0.2	-0.1	-0.1	-0.3	0.3	0.3	0.1	-0.2	-0.2	0.2
C	-0.1	0	0	0	0	0	0	0	0.1	-0.1	0	0	0	0	0	-0.1	0	0	0	0

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0176	0.8	-0.7	-0.3	0.1	0	-0.5	-0.6	-0.7	0.4	0.7	0	-0.2	-0.3	0.4	0.4	0.4	0.4	0.5	0.4	-0.7
0177	0.4	-0.5	-0.1	0	0.1	-0.3	-0.9	-0.3	0.9	1	-0.1	-0.1	-0.8	0.1	0.3	0.8	0	0.1	0.1	-0.3

Select residue pair below:

i_j	Score	Prob
0169_0176	0.884	0.33
0173_0176	0.869	0.31
0176_0208	0.864	0.31
0176_0179	0.851	0.30
0171_0176	0.795	0.25

Local Interactions:

i_j	Score	Prob
0176_0177	1.174	0.62
0175_0176	1.027	0.47
0174_0176	1.000	0.44
0176_0178	0.783	0.24

See all coupling residues
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