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PRMT5 1-300 Return to Main Page

Instructions
  • Use the menu to the right to browse the coupling matrix.

Coupling matrix for [I:0168] and [E:0169]
- A F I L V M W Y D E K R H N Q S T G P C
A 0 -0.1 -0.1 -0.3 0.2 -0.1 0 -0.1 -0.2 0.2 0.5 0.4 -0.1 0.1 0.3 -0.3 0 0.1 0 -0.1
F 0.2 0 0 -0.1 -0.1 0 0 0 0.1 -0.2 -0.1 -0.1 0 0.3 0.4 0 -0.2 -0.1 -0.1 -0.1
I -0.4 -0.1 0 -0.2 0.1 -0.1 0 0 0.3 1 -0.2 -0.2 -0.1 0.1 -0.1 -0.4 0.1 0.3 -0.2 0.1
L -0.2 0.4 0 -0.1 -0.1 -0.1 0 0 0.3 0.1 0.3 -0.2 -0.1 0.2 -0.1 0.2 -0.3 -0.1 -0.2 0.3
V 0.5 0 0 -0.2 -0.1 -0.1 0 0 0.1 -0.2 -0.2 -0.2 0.4 0.7 -0.1 0.3 -0.4 -0.1 -0.1 0.3
M -0.1 0 0 0.3 0 0 0 0 0.1 0.3 -0.1 -0.1 0 -0.1 0 -0.1 -0.1 -0.1 -0.1 0
W -0.1 0 0 -0.1 0 0 0 0 -0.1 -0.1 0 -0.1 0 -0.1 0 -0.1 -0.1 0 0 0.6
Y 0 0 0 -0.1 0 0 0 0 -0.1 -0.1 0 -0.1 0 -0.1 0 -0.1 0.3 0 0 0
D -0.2 -0.1 0 0.1 -0.1 -0.1 0 0 -0.3 0.6 -0.1 -0.2 -0.1 -0.2 -0.1 0.5 0.4 0 -0.2 -0.1
E 0 -0.1 -0.1 0.8 -0.2 -0.1 0 -0.1 -0.1 0.3 -0.2 -0.3 0.3 -0.3 -0.2 0.1 1.5 -0.2 -0.3 -0.2
K -0.1 0 0 -0.1 -0.1 0 0 0 -0.1 -0.1 -0.1 0.3 0 -0.1 0 -0.1 0.2 -0.1 -0.1 0
R 0.1 -0.1 -0.1 -0.3 -0.2 -0.1 -0.1 -0.1 0.1 0 0.1 0.7 -0.1 -0.2 -0.1 0.5 0 0.1 0.1 -0.2
H -0.2 0 0 0.3 0.3 -0.1 0 0 -0.2 -0.2 -0.1 0.5 0 0.3 0.4 -0.2 -0.2 -0.1 -0.1 -0.1
N -0.2 0 0 -0.1 -0.1 -0.1 0 0 -0.2 -0.2 0.6 -0.1 -0.1 -0.2 -0.1 0.1 0 0.7 0.1 -0.1
Q -0.1 0 0 -0.1 0 0 0 0 0.4 -0.1 -0.1 -0.1 0 -0.1 0 -0.2 0.6 -0.1 -0.1 0
S 0.1 -0.1 -0.1 -0.3 0.5 0.3 0 -0.1 -0.4 -0.5 0.1 0.5 -0.1 0.3 -0.2 0.2 0 0 0.7 -0.1
T -0.2 0 0 -0.1 -0.1 -0.1 0 0 0.1 -0.2 -0.1 0.3 0.2 -0.2 -0.1 -0.3 0 -0.1 0.7 -0.1
G 0.1 -0.1 -0.1 0.2 0.2 -0.2 -0.1 0.2 1.3 0.3 0.1 -0.4 -0.2 0 -0.2 0 -0.3 0 0 -0.2
P 1.1 0 0.2 0.5 -0.1 0.8 0 0 -0.4 -0.3 -0.1 -0.3 -0.1 -0.3 -0.1 0.3 -0.3 -0.2 -0.2 -0.1
C -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0 -0.1 0 -0.1 0 0.4 -0.1 -0.1 0 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0168 0.4 -0.2 0.2 0.1 0.3 -0.6 -0.6 -0.8 0.2 0.5 -0.4 0.6 -0.1 0 -0.5 0.7 0 0.9 0.1 -0.8
0169 0.2 -0.6 -0.7 0.1 -0.1 -0.4 -0.8 -0.6 0.9 0.5 0.1 0.3 -0.5 0.4 -0.4 0.6 1.1 -0.1 0.1 -0.2
Select residue pair below:
i_j Score Prob
0169_0176 0.884 0.33
0169_0172 0.797 0.25
0169_0274 0.783 0.24
Local Interactions:
i_j Score Prob
0168_0169 1.085 0.53
0169_0171 0.906 0.35
0169_0170 0.797 0.25
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M A A M A ...

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