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PRMT5 1-300 Return to Main Page

Instructions
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Coupling matrix for [I:0167] and [H:0175]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.5 -0.1 -0.1 -0.2 0.2 -0.1 -0.1 -0.1 0.1 -0.5 -0.1 -0.2 -0.1 0 0.5 0.3 0.1 0.1 0.1 0
F -0.1 0 0 0 -0.1 0 0 0 0.3 -0.1 0.3 -0.1 0 0 -0.1 -0.1 -0.1 -0.1 -0.1 0
I 0 0 -0.1 0.2 -0.1 -0.1 0.2 -0.1 -0.3 -0.1 0.1 -0.1 0.2 -0.1 -0.2 0 0.2 0.4 0 0
L 0.7 -0.1 -0.1 -0.2 0 -0.1 -0.1 -0.1 -0.3 0 0.1 -0.3 -0.1 0.5 0.1 0.3 0.3 -0.1 -0.1 0.1
V -0.2 -0.1 0.1 -0.1 0.4 -0.1 -0.1 0.1 0.4 0.3 -0.1 -0.2 -0.2 -0.2 0 0.1 -0.3 -0.2 0.5 -0.1
M -0.4 0 -0.1 -0.2 -0.1 -0.1 0.2 -0.1 0.1 0.3 -0.1 0.4 -0.1 -0.1 0.2 0 0 0.3 -0.2 0
W 0.1 0 -0.1 -0.1 -0.1 0 0 0 -0.1 0.2 -0.2 -0.1 0 0.1 -0.1 -0.1 0.1 0.2 -0.1 0
Y 0.1 0 0.4 0.2 -0.1 0 0 0 -0.1 0.1 0.5 0.3 -0.1 -0.1 -0.1 -0.2 -0.1 -0.2 -0.1 0
D 0.4 0 -0.1 0.1 -0.1 0.3 -0.1 0 0 0.4 -0.2 -0.1 0 -0.1 -0.1 -0.1 -0.3 0 -0.1 0
E 0.3 0 0.3 -0.1 0.2 0 0 0 0.5 -0.2 -0.2 -0.1 -0.1 -0.1 -0.1 0 0.3 -0.3 -0.3 0
K -0.1 0 0 -0.1 0 0 0 0 -0.1 -0.1 0 0 0 0 0.2 -0.1 -0.1 0.2 -0.1 0
R -0.1 0 0 0 0 0 0 0 -0.1 -0.1 -0.1 0 0 0.1 0 0 0.3 -0.1 0.2 0
H 0.1 0 0 0 0 0 0 0 0 0.1 0 -0.1 0 0.2 -0.1 0.2 -0.1 -0.1 -0.1 0
N 0.1 0 0 0 0 0 0 0 0.2 -0.1 -0.1 -0.1 0 -0.1 0 -0.1 -0.1 0.2 -0.1 0
Q -0.1 0 0 0 0 0 0 0 0 -0.1 0.3 0 0 0 0 -0.1 0.2 -0.1 -0.1 0
S -0.3 0 -0.1 0.2 0.4 -0.1 -0.1 0 -0.2 0.2 0 0.2 -0.1 0.3 -0.2 -0.3 0.1 -0.4 0.4 0
T 0 0 0 0.3 -0.1 0 0 0 -0.2 -0.3 0.4 -0.1 0.2 -0.1 -0.1 -0.2 0 0.1 0 0
G -0.1 0.2 -0.1 0.1 -0.2 -0.1 -0.1 0 -0.3 -0.3 -0.2 -0.1 0.4 -0.1 0.6 0.1 0.2 0.2 0.2 0
P -0.4 0 -0.1 -0.2 0 0.2 -0.1 0.3 -0.2 0.1 0 0.2 -0.1 -0.1 0 0.2 -0.1 0.4 0.1 0
C -0.1 0 0 0 0 0 0 0 0.3 -0.1 -0.1 0 0 0 0 0 -0.1 -0.1 -0.1 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0167 0.4 -0.4 0.1 0.8 0.5 -0.1 -0.3 0 0 -0.2 -0.3 -0.4 -0.1 -0.1 -0.4 0 0.2 0.4 0.3 -0.3
0175 0.4 -0.6 -0.2 -0.2 0 -0.4 -0.4 -0.5 0.3 0.5 0.5 0 -0.3 0.1 0.1 0.3 0.5 0.6 0.2 -0.6
Select residue pair below:
i_j Score Prob
0175_0178 1.002 0.44
0171_0175 0.969 0.41
0175_0179 0.944 0.38
0167_0175 0.894 0.34
0170_0175 0.843 0.29
0168_0175 0.806 0.26
0175_0254 0.780 0.24
Local Interactions:
i_j Score Prob
0174_0175 1.788 0.95
0175_0177 1.194 0.64
0173_0175 1.129 0.57
0175_0176 1.027 0.47
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M A A M A ...

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