OPENSEQ.org -1515484907- GREMLIN Submission

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PRMT5 1-300

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Coupling matrix for [I:0142] and [C:0196]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0.1	0	0.1	0.2	-0.2	0.4	0	0	0	0	0	0	0	-0.1	0	0.4	-0.2	0	0	-0.1
F	-0.4	0	0	-0.2	0.3	-0.1	0	0	0	0	0	-0.1	0	0.8	0	-0.1	-0.3	-0.1	0	0.6
I	0.9	-0.1	0.3	-0.5	-0.3	-0.2	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.2	-0.1	-0.1	0.2	0.3	-0.1	0.8
L	-0.1	0.3	-0.2	-0.4	0.5	-0.4	-0.1	-0.1	0.1	-0.1	-0.1	-0.3	-0.1	0	-0.1	0.1	-0.3	-0.1	-0.1	1.4
V	0.5	-0.1	-0.1	0.4	-0.2	-0.1	0	0	-0.1	0	0	-0.1	0	-0.1	0	-0.1	0.4	-0.1	0	0.4
M	0.3	0	-0.1	0.1	-0.2	0.4	0	0	0	0	0	-0.1	0	-0.1	0	-0.1	-0.2	-0.1	0	0.7
W	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2
Y	-0.1	0	0	0.3	-0.1	0.5	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	-0.3
D	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2
E	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2
K	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2
R	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2
H	0.3	0	0	0.4	-0.1	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	-0.3
N	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2
Q	-0.1	0	0	-0.1	-0.1	0	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0.2
S	-0.3	0	0.2	0.1	0.2	-0.1	0	0	0	0	0	0.5	0	-0.1	0	-0.1	0.5	-0.1	0	-0.2
T	0.1	0	-0.1	-0.2	0.7	-0.1	0	0	0	0	0	0	0	-0.1	0	-0.1	0.3	0	0	-0.3
G	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2
P	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	-0.2
C	-0.1	0	0	0.4	-0.1	0	0	0	0	0	0	0	0	0	0	0	0.4	0	0	-0.3

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0142	0.6	0.5	0.9	1	0.9	0.5	-0.6	-0.1	-0.6	-0.6	-0.6	-0.6	0	-0.6	-0.3	0.7	0.2	-0.6	-0.6	0
0196	1.3	-0.3	-0.1	0.8	0.6	0.1	-0.6	-0.6	-0.4	-0.6	-0.6	-0.3	-0.6	0	-0.6	-0.1	0.6	-0.2	-0.6	1.9

Select residue pair below:

i_j	Score	Prob
0142_0202	2.016	0.98
0142_0196	1.239	0.68
0096_0142	0.822	0.27
0045_0142	0.816	0.27

Local Interactions:

i_j

Score

Prob

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