OPENSEQ.org -1515484907- GREMLIN Submission

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PRMT5 1-300

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Coupling matrix for [Q:0128] and [M:0249]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	-0.4	-0.1	0	0	-0.1	0	0	0	0	0.4	-0.1	-0.2	0.6	-0.1	0.5	-0.1	-0.1	-0.1	-0.2	0
F	-0.2	0	0	0.5	0	0	0	0	0	0	-0.1	-0.1	-0.1	0	0	-0.1	0	-0.1	-0.1	0
I	0.5	-0.1	0	0	-0.1	-0.1	0	0	0	-0.1	-0.1	-0.3	-0.2	-0.1	0.5	-0.2	0	0.3	-0.2	0
L	-0.2	-0.1	-0.1	-0.1	-0.1	-0.1	0	-0.1	-0.1	-0.1	0.3	0.1	0.5	-0.1	-0.1	-0.3	-0.1	0.2	0.4	-0.1
V	-0.2	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	-0.1	0	0	-0.1	0
M	-0.3	-0.1	0	0	-0.1	0	0	0	0	0.5	-0.1	-0.1	-0.2	0.5	0	-0.1	0	-0.1	-0.1	0
W	-0.2	0	0	0	0	0	0	0	0	0	0	-0.1	0	0	0	-0.1	0	0	-0.1	0
Y	-0.1	0	0	0	0	0	0	0	0	0	0	-0.1	-0.1	0	0	-0.1	0	-0.1	-0.1	0
D	0.2	-0.1	0	-0.1	-0.1	-0.1	0	-0.1	-0.1	-0.1	-0.2	0.8	-0.2	-0.1	-0.1	-0.2	-0.1	-0.2	0.6	0
E	-0.4	-0.1	0.5	0	-0.1	0	0	0	0	-0.1	-0.1	0.3	0.6	-0.1	-0.1	-0.1	0	-0.1	-0.2	0
K	-0.2	0.7	-0.3	-0.4	0.5	0	-0.1	0.4	1	0.1	-0.5	0.8	-0.8	-0.4	-0.4	0.8	0.3	-0.4	-0.3	0.6
R	0.1	0.9	-0.1	0.3	0.2	-0.6	-0.1	0.1	-0.1	-0.7	-0.3	-0.4	0.7	0.1	-0.6	0.4	0.5	0.5	0.2	-0.4
H	1	-0.1	-0.1	-0.1	-0.1	0.4	0	-0.1	-0.1	-0.1	-0.2	-0.4	-0.2	-0.1	0.4	-0.1	-0.1	0.1	0.3	-0.1
N	0.2	-0.1	0.4	-0.1	-0.1	-0.1	0	-0.1	-0.1	-0.1	0.2	-0.3	-0.3	-0.1	-0.1	0.4	-0.1	-0.1	0.5	-0.1
Q	-0.6	0.3	-0.1	-0.1	0.7	1	0	0.4	-0.1	-0.2	-0.3	-0.5	0	-0.1	-0.1	0.3	-0.1	-0.2	0	-0.1
S	1.5	-0.3	-0.1	0.3	-0.2	-0.2	0	-0.2	-0.1	-0.2	0.3	-0.3	0.3	0.1	-0.2	0.1	-0.2	0.3	-0.3	0.3
T	-0.5	-0.1	0	-0.1	-0.1	-0.1	0	-0.1	-0.1	-0.1	1.4	0.4	0.2	-0.1	-0.1	-0.2	-0.1	-0.2	-0.3	0
G	0.6	-0.4	-0.2	-0.2	-0.3	-0.2	-0.1	-0.2	-0.2	1.1	-0.5	0.1	-0.2	0.4	0.5	0	0	0.6	0.3	-0.2
P	0	-0.1	0	0	0	0	0	0	0	-0.1	-0.1	0.6	-0.1	0	0	-0.1	0	-0.1	-0.1	0
C	-0.1	0	0	0	0	0	0	0	0	0	0.4	-0.1	-0.1	0	0	-0.1	0	-0.1	-0.1	0

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0128	-0.4	-0.9	-0.4	0.1	-1.1	-0.7	-1.1	-1.1	0	-0.4	2	2.5	0.3	0.3	0.6	1	-0.1	1.3	-0.6	-0.8
0249	1.3	0.2	-0.4	-0.4	0	-0.4	-0.9	-0.3	-0.4	0.3	0.7	0.3	0.8	-0.2	-0.3	0.2	-0.1	0.1	0.2	-0.3

Select residue pair below:

i_j	Score	Prob
0212_0249	1.282	0.72
0204_0249	0.991	0.43
0128_0249	0.830	0.28

Local Interactions:

i_j

Score

Prob

See all coupling residues
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