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PRMT5 1-300 Return to Main Page

Instructions
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Coupling matrix for [G:0011] and [N:0021]
- A F I L V M W Y D E K R H N Q S T G P C
A -0.1 -0.1 -0.1 0 -0.1 0 0 0.5 0.4 -0.1 -0.1 0 -0.2 0 0 0.3 -0.1 0.3 -0.1 -0.2
F 0 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0
I 0 0 0 0 0 0 0 0 -0.1 -0.1 0 0 -0.1 -0.1 0 0 0 0 0.4 -0.1
L -0.1 0 0 0 0 0 0 0 0.6 -0.1 -0.1 0 -0.1 0.2 0 -0.1 -0.1 -0.1 -0.1 -0.1
V -0.1 0 0 0 0 0 0 0 -0.1 -0.1 0 0 -0.2 0.3 0 -0.1 0 -0.1 0 0.4
M -0.1 0 0 0 0 0 0 0 -0.2 -0.1 0.5 0 -0.1 0.1 0 -0.1 0 0 0 -0.1
W 0 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0
Y 0 0 0 0 0 0 0 0 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0
D -0.1 -0.1 0 0 0 0 0 0 0.3 -0.1 0.4 0 -0.1 -0.1 0 -0.1 0 -0.1 -0.1 -0.1
E -0.1 0.4 0 0 0 0 0 0 -0.1 -0.1 0 0 -0.1 -0.1 0 -0.1 0 -0.1 -0.1 0.3
K -0.1 -0.1 -0.1 0 -0.1 0 0 0 0.6 0 -0.1 0 -0.2 0.6 0 -0.2 0.4 -0.1 -0.1 -0.2
R -0.2 -0.1 -0.1 -0.1 0.3 0 0 0 -0.1 -0.2 -0.1 0 1.1 0.4 -0.1 -0.1 -0.1 -0.1 -0.1 -0.3
H -0.1 0 -0.1 0 0 0 0 0 -0.2 -0.1 -0.1 0 0.3 0.3 0 -0.1 0 -0.1 -0.1 0.2
N -0.1 0 0.4 0 0 0 0 0 0.2 0.5 -0.1 0 -0.1 -0.1 0 -0.1 -0.1 -0.1 -0.1 0
Q -0.2 -0.1 -0.1 0 -0.1 0 0 0 -0.3 0.5 -0.1 0 0.2 -0.3 -0.1 0.7 -0.1 -0.1 -0.2 0.9
S -0.3 0.2 0.1 0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.5 0.2 0.2 -0.1 -0.5 0.3 -0.4 0.2 0.7 -0.4 0.5
T 0.8 -0.1 -0.1 0 -0.1 0 0 0 -0.1 -0.2 -0.1 0 0.2 -0.2 0 -0.1 0 0.4 -0.1 -0.2
G 0.2 0.4 0.4 -0.1 -0.1 0 0 0 0.7 -0.2 -0.1 0 -0.2 0.1 -0.1 -0.1 -0.1 -0.1 -0.2 -0.2
P -0.1 -0.1 -0.1 0 0 0 0 0 -0.2 0.6 -0.1 0 -0.1 -0.2 0 -0.1 0.4 -0.1 0.3 -0.1
C 0.4 0 -0.1 0 0 0 0 0 -0.2 -0.1 0 0 -0.1 -0.1 0 -0.1 0 0 0.4 -0.1

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0011 0.1 -0.7 -0.5 -0.2 -0.3 -0.4 -0.7 -0.7 -0.3 -0.4 0.2 0.2 -0.2 0 0.6 1.2 0 0.3 0 -0.3
0021 0.2 -0.3 -0.2 -0.1 -0.4 -0.7 -0.7 -0.5 1 0.6 -0.1 -0.2 0.2 0.6 -0.1 0.4 0.3 0.2 0.3 -0.1
Select residue pair below:
i_j Score Prob
0013_0021 1.005 0.45
0018_0021 0.989 0.43
0011_0021 0.805 0.26
Local Interactions:
i_j Score Prob
0020_0021 0.930 0.37
0021_0023 0.877 0.32
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M A A M A ...

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