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Instructions
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Coupling matrix for [V:0192] and [I:0213]
- A F I L V M W Y D E K R H N Q S T G P C
A -0.3 -0.5 -0.6 0.1 -0.1 0.3 -0.2 -0.6 -0.1 -0.2 -0.1 0 0.5 -0.1 0.4 1 0.2 -0.4 0.3 0.8
F -0.1 0 -0.2 -0.1 0 0.2 0 -0.1 0 -0.1 -0.1 -0.1 0 0 0 0 0.3 0 -0.1 0
I 0.4 0.3 0.6 0.6 -0.1 0.7 -0.1 -0.3 -0.2 -0.3 -0.6 -0.2 0.3 0.1 0 -0.1 -0.2 0.1 -0.6 0
L -0.4 -0.4 0.9 0.9 0 0.4 -0.1 -0.3 0.2 0.3 -0.5 0 -0.2 -0.1 -0.3 -0.3 0 -0.1 -0.4 0.6
V -0.5 -0.2 0.7 0.5 0.4 0.5 -0.3 -0.8 -0.5 0.7 -0.1 0.5 0.4 -0.1 -0.3 0.2 0.1 -0.1 -0.5 -0.5
M -0.1 -0.1 0.2 0.2 0 -0.1 0 -0.1 0 -0.1 0.4 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0 -0.1 0
W 0 0 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Y 0.2 -0.1 -0.2 0 -0.5 -0.2 0 -0.1 -0.1 0.4 0.1 0.1 -0.1 -0.1 -0.1 -0.1 0.8 -0.1 -0.1 -0.1
D 0 0.3 0.2 -0.2 0 -0.3 0 -0.2 -0.1 -0.2 0 -0.2 -0.1 -0.1 -0.2 -0.2 0 0.7 0.3 0.3
E -0.3 -0.3 0.1 -0.1 0.2 0.2 -0.3 0.3 0.2 -0.4 0.6 -0.5 0.2 0.6 -0.1 0.2 -0.3 0.4 0 -0.4
K 0 0.2 0.5 -0.1 0.7 -0.7 0.3 0.7 -0.4 -0.5 -0.1 0.2 0 -0.2 0.5 0.4 -0.4 -0.1 -0.2 -0.4
R 0.2 -0.1 0.2 -0.6 0.8 0.1 -0.1 -0.2 0.3 0 -0.3 -0.4 -0.2 -0.2 0.1 -0.3 0.2 -0.2 0.6 0.2
H -0.2 -0.2 -0.7 -0.1 0 -0.1 0 0.4 -0.1 0.5 0 -0.1 -0.1 0.3 -0.1 -0.2 -0.1 -0.1 0.8 -0.1
N -0.3 0.2 0.1 -0.1 -0.1 -0.2 -0.1 0.7 -0.1 0.2 0 -0.1 -0.1 0.3 0.3 -0.2 -0.1 -0.1 -0.1 -0.1
Q 0.3 0.3 0.4 -0.6 0.5 -0.5 -0.1 0.1 0.7 -0.3 0 0 -0.1 -0.1 -0.3 -0.1 0.1 -0.1 0.4 -0.2
S -0.1 -0.3 0.1 0.1 -0.2 -0.4 -0.1 1.1 0.1 0.1 0.2 0.3 -0.2 -0.2 0 0 0 -0.1 0.1 -0.2
T 0.4 0.4 -0.4 -0.1 -0.3 -0.3 0.7 0.2 -0.1 -0.4 0.5 0.6 -0.3 0 0 -0.5 0.1 -0.2 0.1 -0.2
G -0.1 0 -0.4 -0.1 -0.2 -0.1 0.4 -0.1 0 -0.1 -0.1 -0.1 0.3 0 -0.1 -0.1 0 0.4 0.3 0
P 0.2 0.9 -0.6 0.4 0.3 0.5 -0.4 0 0 -0.5 -0.1 0.3 -0.5 -0.4 0.3 0.3 -0.1 -0.1 -0.2 0.1
C 0.1 -0.1 -0.1 -0.1 -0.1 0.4 0 -0.2 -0.1 0.2 0.5 0 0.3 -0.1 -0.1 -0.1 -0.2 -0.1 -0.2 -0.1

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0192 0.9 -1 0.2 0.6 0.2 -0.7 -1.4 -0.9 -0.1 0.8 0.8 0 -0.5 0 0.3 0.5 0.3 -0.5 1.1 -0.1
0213 0.3 -0.1 1.2 1 1.1 0 -1.2 0.4 -0.7 -0.1 0.9 0.1 -0.4 -0.5 -0.1 0.2 0 -0.7 0.2 -0.6
Select residue pair below:
i_j Score Prob
0092_0096 4.209 1.00
0110_0141 3.745 1.00
0117_0128 3.366 1.00
0220_0240 3.201 1.00
0197_0241 3.188 1.00
0174_0178 3.123 1.00
0117_0130 2.799 1.00
0076_0141 2.461 1.00
0100_0105 2.402 1.00
0200_0239 2.144 1.00
0120_0131 2.131 1.00
0195_0207 2.085 1.00
0194_0242 2.070 1.00
0212_0221 2.036 1.00
0083_0088 1.962 1.00
0197_0207 1.933 1.00
0115_0130 1.884 1.00
0098_0156 1.734 1.00
0089_0115 1.714 1.00
0091_0159 1.700 1.00
0119_0126 1.684 1.00
0118_0131 1.658 1.00
0121_0126 1.635 1.00
0109_0141 1.630 1.00
0214_0217 1.600 1.00
0173_0176 1.556 1.00
0219_0234 1.522 1.00
0119_0128 1.506 1.00
0141_0174 1.486 1.00
0196_0208 1.477 1.00
0093_0097 1.467 1.00
0082_0161 1.460 1.00
0191_0194 1.457 1.00
0087_0090 1.454 1.00
0107_0145 1.443 1.00
0116_0131 1.441 1.00
0220_0237 1.433 1.00
0211_0223 1.432 1.00
0208_0222 1.420 1.00
0134_0180 1.416 1.00
0196_0222 1.416 1.00
0081_0159 1.378 0.99
0075_0143 1.367 0.99
0225_0230 1.347 0.99
0236_0239 1.342 0.99
0190_0210 1.341 0.99
0076_0109 1.332 0.99
0198_0235 1.318 0.99
0199_0241 1.303 0.99
0223_0230 1.295 0.99
0082_0160 1.283 0.99
0087_0158 1.281 0.99
0095_0099 1.263 0.99
0084_0087 1.245 0.98
0081_0153 1.231 0.98
0209_0223 1.228 0.98
0112_0184 1.223 0.98
0099_0108 1.216 0.98
0088_0113 1.210 0.98
0090_0158 1.205 0.98
0153_0159 1.204 0.98
0235_0239 1.197 0.98
0139_0177 1.189 0.98
0175_0179 1.188 0.98
0142_0149 1.185 0.98
0134_0139 1.180 0.98
0197_0205 1.176 0.98
0221_0234 1.166 0.97
0145_0149 1.149 0.97
0222_0235 1.146 0.97
0134_0158 1.141 0.97
0110_0181 1.140 0.97
0142_0153 1.117 0.96
0221_0232 1.115 0.96
0092_0111 1.095 0.96
0122_0127 1.093 0.96
0077_0174 1.081 0.95
0092_0113 1.081 0.95
0175_0178 1.078 0.95
0195_0209 1.071 0.95
0139_0172 1.063 0.95
0082_0136 1.051 0.94
0080_0163 1.036 0.94
0215_0237 1.035 0.94
0151_0154 1.033 0.94
0096_0111 1.017 0.93
0227_0231 1.012 0.93
0177_0181 1.011 0.93
0211_0221 1.009 0.93
0172_0177 1.008 0.93
0094_0156 1.006 0.93
0150_0154 0.987 0.92
0099_0106 0.982 0.91
0104_0107 0.981 0.91
0219_0236 0.979 0.91
0120_0129 0.971 0.91
0113_0138 0.969 0.91
0223_0232 0.968 0.91
0178_0182 0.958 0.90
0095_0153 0.946 0.89
0142_0150 0.936 0.89
0090_0093 0.935 0.89
0081_0140 0.929 0.88
0091_0156 0.917 0.87
0215_0218 0.897 0.86
0083_0087 0.890 0.85
0095_0159 0.890 0.85
0146_0168 0.880 0.84
0192_0213 0.876 0.84
0091_0138 0.866 0.83
0077_0171 0.862 0.82
0123_0127 0.855 0.82
0235_0240 0.854 0.82
0134_0137 0.853 0.81
0105_0108 0.852 0.81
0226_0229 0.851 0.81
0087_0094 0.850 0.81
0099_0103 0.850 0.81
0208_0233 0.845 0.81
0133_0139 0.838 0.80
0121_0124 0.837 0.80
0210_0213 0.828 0.79
0178_0181 0.828 0.79
0080_0172 0.827 0.79
0083_0091 0.825 0.78
0179_0183 0.824 0.78
0112_0181 0.823 0.78
0214_0219 0.822 0.78
0076_0143 0.821 0.78
0226_0231 0.815 0.77
0198_0201 0.806 0.76
0101_0104 0.800 0.75
0095_0098 0.784 0.73
0202_0206 0.781 0.73
0099_0105 0.780 0.73
0211_0232 0.778 0.72
0200_0204 0.775 0.72
0224_0233 0.774 0.72
0228_0231 0.774 0.72
0149_0152 0.772 0.72
0154_0161 0.770 0.71
0094_0098 0.770 0.71
0101_0106 0.768 0.71
0192_0212 0.767 0.71
0121_0125 0.762 0.70
0076_0110 0.756 0.69
0139_0180 0.755 0.69
0096_0100 0.754 0.69
0196_0240 0.750 0.68
0107_0143 0.750 0.68
0238_0242 0.744 0.68
0165_0168 0.743 0.67
0165_0170 0.738 0.67
0218_0238 0.737 0.67
0190_0194 0.732 0.66
0135_0219 0.730 0.65
0098_0102 0.727 0.65
0101_0107 0.721 0.64
0089_0093 0.719 0.64
0222_0240 0.719 0.64
0151_0155 0.717 0.63
0122_0125 0.716 0.63
0088_0136 0.714 0.63
0190_0240 0.712 0.63
0160_0164 0.709 0.62
0098_0101 0.709 0.62
0096_0110 0.703 0.61
0102_0139 0.698 0.60
0152_0155 0.697 0.60
0102_0105 0.696 0.60
0071_0074 0.689 0.59
0189_0242 0.679 0.57
0164_0171 0.676 0.57
0103_0106 0.673 0.56
0098_0152 0.671 0.56
0190_0237 0.669 0.55
0164_0169 0.666 0.55
0218_0237 0.664 0.55
0153_0162 0.663 0.54
0089_0092 0.663 0.54
0145_0148 0.662 0.54
0098_0155 0.659 0.54
0088_0137 0.659 0.54
0137_0156 0.657 0.53
0093_0096 0.657 0.53
0112_0139 0.657 0.53
0090_0142 0.657 0.53
0150_0164 0.657 0.53
0102_0106 0.655 0.53
0124_0201 0.654 0.53
0191_0242 0.651 0.52
0112_0117 0.651 0.52
0082_0087 0.643 0.51
0183_0203 0.640 0.50
0150_0163 0.640 0.50
0159_0169 0.640 0.50
0107_0148 0.637 0.50
0106_0109 0.635 0.50
0163_0229 0.634 0.49
0198_0208 0.631 0.49
0213_0237 0.631 0.49
0081_0138 0.630 0.49
0192_0210 0.627 0.48
0102_0157 0.626 0.48
0206_0231 0.623 0.48
0133_0180 0.620 0.47
0092_0099 0.619 0.47
0224_0229 0.618 0.47
0104_0149 0.618 0.47
0101_0105 0.618 0.47
0104_0134 0.617 0.47
0210_0240 0.615 0.46
0100_0103 0.614 0.46
0102_0107 0.610 0.45
0098_0146 0.607 0.45
0149_0153 0.606 0.45
0192_0211 0.599 0.43
0211_0222 0.599 0.43
0144_0150 0.598 0.43
0099_0102 0.594 0.43
0203_0208 0.593 0.42
0163_0170 0.593 0.42
0091_0210 0.592 0.42
0224_0231 0.590 0.42
0161_0164 0.590 0.42
0104_0152 0.589 0.42
0097_0133 0.586 0.41
0122_0128 0.584 0.41
0099_0140 0.584 0.41
0135_0226 0.583 0.41
0080_0176 0.581 0.40
0201_0204 0.581 0.40
0193_0196 0.579 0.40
0089_0132 0.579 0.40
0114_0193 0.577 0.40
0077_0153 0.577 0.40
0083_0160 0.575 0.39
0150_0169 0.574 0.39
0224_0232 0.570 0.39
0136_0164 0.570 0.39
0094_0157 0.569 0.39
0101_0180 0.569 0.39
0188_0195 0.568 0.38
0121_0139 0.567 0.38
0115_0132 0.567 0.38
0099_0107 0.566 0.38
0086_0136 0.565 0.38
0140_0162 0.563 0.38
0088_0208 0.560 0.37
0111_0138 0.558 0.37
0093_0149 0.557 0.37
0194_0220 0.557 0.37
0095_0156 0.557 0.37
0217_0242 0.557 0.37
0234_0239 0.557 0.37
0169_0203 0.553 0.36
0142_0164 0.551 0.36
0085_0136 0.550 0.35
Local Interactions:
i_j Score Prob
0123_0124 2.573 1.00
0204_0205 2.035 1.00
0214_0215 1.994 1.00
0127_0129 1.921 1.00
0209_0211 1.752 1.00
0236_0238 1.731 1.00
0124_0125 1.706 1.00
0106_0107 1.676 1.00
0122_0123 1.617 1.00
0173_0175 1.609 1.00
0103_0105 1.567 1.00
0199_0200 1.522 1.00
0092_0093 1.512 1.00
0226_0227 1.436 1.00
0170_0171 1.382 0.99
0227_0229 1.319 0.99
0071_0072 1.315 0.99
0104_0105 1.312 0.99
0116_0118 1.274 0.99
0073_0074 1.268 0.99
0110_0112 1.254 0.99
0201_0202 1.234 0.98
0172_0173 1.220 0.98
0108_0109 1.212 0.98
0236_0237 1.205 0.98
0201_0203 1.191 0.98
0075_0076 1.183 0.98
0227_0228 1.172 0.98
0097_0098 1.161 0.97
0072_0073 1.144 0.97
0122_0124 1.117 0.96
0101_0102 1.113 0.96
0212_0214 1.102 0.96
0075_0077 1.066 0.95
0076_0077 1.056 0.95
0107_0108 1.044 0.94
0077_0079 1.043 0.94
0125_0127 1.038 0.94
0118_0119 1.022 0.93
0184_0185 1.003 0.93
0160_0161 0.999 0.92
0191_0192 0.993 0.92
0104_0106 0.987 0.92
0154_0155 0.981 0.91
0105_0107 0.961 0.90
0109_0111 0.933 0.88
0120_0122 0.932 0.88
0107_0109 0.919 0.87
0072_0074 0.915 0.87
0167_0168 0.907 0.86
0074_0075 0.894 0.85
0126_0127 0.893 0.85
0200_0201 0.890 0.85
0102_0103 0.889 0.85
0103_0104 0.878 0.84
0166_0167 0.870 0.83
0226_0228 0.842 0.80
0071_0073 0.842 0.80
0105_0106 0.837 0.80
0155_0156 0.832 0.79
0214_0216 0.822 0.78
0194_0196 0.820 0.78
0144_0145 0.819 0.78
0081_0083 0.818 0.78
0086_0088 0.813 0.77
0085_0086 0.811 0.77
0100_0101 0.805 0.76
0113_0115 0.805 0.76
0197_0199 0.805 0.76
0220_0222 0.804 0.76
0229_0231 0.800 0.75
0188_0190 0.794 0.75
0216_0217 0.794 0.75
0238_0239 0.789 0.74
0205_0207 0.784 0.73
0213_0215 0.783 0.73
0151_0152 0.778 0.72
0093_0094 0.776 0.72
0186_0187 0.764 0.71
0127_0128 0.762 0.70
0102_0104 0.756 0.69
0150_0151 0.752 0.69
0145_0146 0.751 0.69
0073_0075 0.727 0.65
0173_0174 0.717 0.63
0165_0166 0.706 0.62
0231_0233 0.703 0.61
0185_0186 0.687 0.58
0157_0158 0.686 0.58
0084_0085 0.671 0.56
0080_0082 0.665 0.55
0240_0242 0.662 0.54
0192_0193 0.659 0.54
0118_0120 0.657 0.53
0161_0162 0.655 0.53
0169_0170 0.654 0.53
0117_0119 0.645 0.51
0195_0197 0.642 0.51
0209_0210 0.639 0.50
0231_0232 0.633 0.49
0202_0203 0.629 0.49
0223_0225 0.628 0.48
0190_0191 0.612 0.46
0132_0133 0.611 0.46
0124_0126 0.603 0.44
0187_0188 0.596 0.43
0082_0083 0.594 0.43
0101_0103 0.592 0.42
0121_0122 0.590 0.42
0086_0087 0.586 0.41
0188_0189 0.583 0.41
0074_0076 0.578 0.40
0165_0167 0.573 0.39
0215_0216 0.572 0.39
0163_0164 0.565 0.38
0083_0084 0.562 0.37
0228_0229 0.553 0.36
0126_0128 0.552 0.36
0078_0079 0.551 0.36
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M E E K K ...

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