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Instructions
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Coupling matrix for [K:0271] and [G:0272]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.6 0 -0.2 0.5 -0.1 -0.2 0.1 -0.1 -0.2 0.1 -0.2 0.3 0.2 -0.6 0.3 -0.2 -0.5 0.6 0.2 0
F -0.2 -0.1 -0.1 0.4 0.3 -0.1 0 0 -0.2 -0.2 -0.2 0.1 -0.1 0.2 -0.1 -0.2 -0.1 -0.2 0.6 0
I -0.1 0.5 -0.2 -0.5 0.5 -0.1 -0.1 -0.1 0.1 -0.2 0.3 0 -0.2 0.2 -0.2 -0.1 -0.2 0 0 0.4
L -0.6 -0.3 -0.3 0.1 0 0.2 -0.1 -0.1 0.4 0.2 0.1 0.3 0 -0.1 0.1 0.3 0.3 -0.4 0 -0.1
V 0.3 -0.2 -0.2 -0.3 -0.2 -0.1 -0.1 -0.1 0.6 0.1 0 0 -0.2 0 -0.2 0.2 0.4 -0.1 0.2 -0.1
M -0.1 0 -0.1 -0.1 0.1 0 0 0 0 0 -0.1 -0.2 0 -0.1 -0.1 0.2 0.3 -0.1 -0.1 0
W -0.5 -0.2 -0.2 -0.5 -0.2 -0.1 -0.1 -0.1 1.1 0.4 0.4 -0.5 -0.1 0.4 -0.4 0.3 0.2 -0.4 0.2 -0.2
Y -0.3 0.3 0.7 -0.2 0.3 -0.1 0 -0.1 -0.3 0.4 0.2 -0.3 -0.1 -0.2 0.2 0.1 -0.2 -0.3 -0.1 -0.1
D -0.1 0.5 0.2 0.2 0.1 0.2 -0.1 -0.2 0 -0.1 0 0.1 0.1 -0.2 0.1 -0.4 0.4 0.3 -0.3 -0.3
E 0.4 0.3 0.2 0.5 0.3 0.1 -0.2 0.4 -0.3 -0.1 0.4 0.2 -0.3 -0.2 -0.5 -0.1 -0.6 0.1 0.1 0.2
K 0.3 -0.5 0.1 0.4 -0.2 0.5 0.1 0 0 0 -0.1 -0.1 0.5 0.1 0.4 -0.4 0.5 -0.1 -0.6 -0.3
R 0 -0.2 0.1 0 -0.2 0.3 0.2 0 -0.1 0.1 -0.1 -0.1 -0.3 0.4 -0.1 0.1 0.3 -0.3 0 0.2
H -0.1 0.2 0.3 -0.2 -0.1 -0.1 0 0.8 -0.3 -0.3 -0.2 -0.3 -0.1 -0.2 0.2 0.1 -0.2 0.3 -0.1 -0.1
N -0.3 0.6 0.2 0.3 -0.1 -0.1 -0.1 -0.2 0 -0.1 -0.5 0.2 0.4 0.3 0.3 0.3 -0.5 0.3 -0.1 -0.2
Q 0.2 -0.2 -0.2 0 0 -0.2 0.1 -0.2 -0.5 0 0 0.6 0 0.2 0 -0.2 0.6 0.1 -0.4 0.2
S 0.1 -0.3 0.3 0.3 0.1 -0.1 -0.1 -0.3 0 -0.1 0.3 0.3 0.1 -0.1 0.9 -0.4 -0.4 0.1 -0.4 -0.2
T 0.2 0 -0.3 0.1 -0.2 -0.2 -0.1 -0.1 -0.4 0.1 0 0.1 0.4 0.1 -0.4 0.3 0 0.2 0.5 -0.1
G 0.4 -0.2 -0.2 -0.2 0 0 -0.1 -0.2 0.5 0.2 0.4 0.2 -0.5 0 -0.3 0.2 0.2 0 -0.1 0.2
P 0.3 0 -0.2 -0.4 -0.1 -0.2 -0.1 0.2 0.4 0.1 -0.2 -0.3 -0.2 -0.4 0.1 0.2 -0.1 0.6 0.3 0.2
C 0.3 0 0 0.3 -0.1 0 0 0 0 -0.2 -0.1 0 -0.1 -0.1 -0.1 -0.1 0.1 -0.2 0.1 0
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0271 1 -1 -0.3 0.3 -0.4 -1.3 -0.4 -0.8 0.6 1 0.6 0.9 -0.8 0.5 0.2 0.6 0 0.9 0.3 -1.5
0272 0.6 -0.5 -0.4 0.5 -0.3 -0.9 -1.5 -1 0.8 0.6 -0.1 0.5 -0.5 0.1 -0.1 0.6 0.1 0.5 -0.1 -0.9
Select residue pair below:
i_j Score Prob
0054_0259 3.248 1.00
0055_0107 3.171 1.00
0136_0145 2.696 1.00
0125_0203 2.688 1.00
0152_0186 2.528 1.00
0115_0118 2.467 1.00
0213_0258 2.428 1.00
0155_0158 2.425 1.00
0108_0263 2.367 1.00
0256_0261 2.264 1.00
0071_0074 2.263 1.00
0257_0260 2.247 1.00
0155_0177 2.246 1.00
0051_0109 2.238 1.00
0114_0118 2.170 1.00
0174_0177 2.121 1.00
0113_0126 2.114 1.00
0109_0262 2.100 1.00
0112_0266 2.088 1.00
0042_0206 2.057 1.00
0161_0186 2.051 1.00
0256_0260 2.030 1.00
0220_0224 2.026 1.00
0045_0113 2.023 1.00
0115_0119 1.978 1.00
0241_0257 1.930 1.00
0117_0142 1.900 1.00
0162_0183 1.828 1.00
0045_0211 1.804 1.00
0054_0257 1.798 1.00
0112_0263 1.796 1.00
0077_0080 1.738 1.00
0149_0152 1.736 1.00
0105_0137 1.700 1.00
0059_0062 1.675 1.00
0230_0251 1.673 1.00
0079_0191 1.666 1.00
0053_0059 1.655 1.00
0264_0267 1.653 1.00
0220_0223 1.632 1.00
0158_0177 1.627 1.00
0042_0124 1.616 1.00
0133_0137 1.607 1.00
0229_0234 1.598 1.00
0209_0237 1.597 1.00
0239_0261 1.589 1.00
0044_0207 1.586 1.00
0160_0175 1.568 1.00
0078_0082 1.561 1.00
0117_0140 1.556 1.00
0154_0186 1.553 1.00
0109_0258 1.550 1.00
0125_0144 1.547 1.00
0144_0199 1.541 1.00
0047_0135 1.539 1.00
0108_0111 1.523 1.00
0201_0228 1.518 1.00
0155_0174 1.509 1.00
0145_0149 1.477 1.00
0090_0094 1.458 1.00
0235_0252 1.421 1.00
0209_0235 1.413 1.00
0041_0208 1.387 0.99
0099_0104 1.367 0.99
0082_0156 1.357 0.99
0047_0126 1.347 0.99
0086_0090 1.331 0.99
0047_0051 1.307 0.99
0081_0156 1.296 0.99
0243_0255 1.295 0.99
0242_0255 1.286 0.99
0264_0268 1.285 0.99
0158_0174 1.279 0.99
0042_0208 1.274 0.99
0213_0239 1.255 0.99
0154_0161 1.249 0.99
0202_0206 1.241 0.98
0235_0251 1.240 0.98
0112_0115 1.231 0.98
0112_0262 1.230 0.98
0256_0264 1.221 0.98
0160_0176 1.221 0.98
0115_0266 1.206 0.98
0117_0141 1.205 0.98
0058_0069 1.193 0.98
0133_0145 1.189 0.98
0105_0111 1.184 0.98
0108_0112 1.181 0.98
0099_0150 1.178 0.98
0196_0199 1.167 0.97
0213_0262 1.165 0.97
0162_0175 1.163 0.97
0211_0237 1.156 0.97
0081_0184 1.150 0.97
0062_0068 1.124 0.97
0205_0228 1.124 0.97
0044_0210 1.121 0.97
0133_0149 1.120 0.96
0254_0261 1.119 0.96
0092_0095 1.118 0.96
0047_0113 1.109 0.96
0136_0143 1.108 0.96
0108_0259 1.102 0.96
0260_0264 1.095 0.96
0254_0268 1.092 0.96
0033_0237 1.089 0.96
0238_0247 1.088 0.96
0152_0161 1.079 0.95
0156_0182 1.069 0.95
0049_0052 1.067 0.95
0042_0203 1.066 0.95
0146_0222 1.065 0.95
0088_0092 1.065 0.95
0111_0115 1.057 0.95
0070_0087 1.056 0.95
0089_0172 1.051 0.94
0074_0083 1.046 0.94
0116_0266 1.042 0.94
0076_0189 1.034 0.94
0074_0087 1.034 0.94
0057_0104 1.033 0.94
0067_0076 1.029 0.94
0238_0250 1.014 0.93
0114_0138 1.014 0.93
0133_0151 1.009 0.93
0199_0202 1.007 0.93
0081_0189 0.996 0.92
0204_0225 0.995 0.92
0042_0123 0.992 0.92
0153_0183 0.985 0.92
0238_0244 0.978 0.91
0058_0064 0.968 0.91
0125_0143 0.966 0.91
0144_0196 0.963 0.90
0171_0182 0.963 0.90
0204_0210 0.963 0.90
0131_0150 0.959 0.90
0091_0095 0.958 0.90
0188_0191 0.957 0.90
0058_0098 0.954 0.90
0107_0259 0.949 0.89
0052_0056 0.940 0.89
0084_0087 0.935 0.89
0212_0250 0.932 0.88
0112_0116 0.932 0.88
0199_0203 0.932 0.88
0060_0091 0.930 0.88
0184_0189 0.925 0.88
0236_0250 0.924 0.88
0088_0091 0.919 0.87
0061_0065 0.918 0.87
0144_0203 0.912 0.87
0051_0135 0.910 0.87
0244_0247 0.908 0.87
0046_0210 0.908 0.87
0212_0246 0.897 0.86
0115_0267 0.895 0.85
0047_0213 0.893 0.85
0044_0127 0.883 0.84
0135_0140 0.877 0.84
0042_0122 0.874 0.84
0247_0253 0.871 0.83
0033_0252 0.870 0.83
0131_0187 0.865 0.83
0216_0219 0.855 0.82
0094_0098 0.851 0.81
0185_0192 0.849 0.81
0042_0125 0.849 0.81
0097_0167 0.848 0.81
0197_0225 0.845 0.81
0045_0123 0.842 0.80
0044_0204 0.835 0.80
0237_0252 0.833 0.79
0118_0141 0.825 0.78
0217_0238 0.817 0.77
0117_0139 0.813 0.77
0078_0191 0.813 0.77
0031_0035 0.812 0.77
0049_0147 0.811 0.77
0057_0134 0.809 0.77
0075_0080 0.809 0.77
0154_0195 0.808 0.76
0040_0209 0.807 0.76
0071_0080 0.806 0.76
0263_0266 0.803 0.76
0075_0078 0.801 0.76
0099_0102 0.800 0.75
0212_0217 0.798 0.75
0194_0221 0.795 0.75
0041_0122 0.792 0.74
0043_0122 0.785 0.73
0060_0221 0.781 0.73
0109_0213 0.780 0.73
0227_0249 0.777 0.72
0267_0271 0.777 0.72
0109_0259 0.776 0.72
0114_0140 0.774 0.72
0102_0165 0.771 0.71
0184_0192 0.765 0.71
0126_0135 0.764 0.71
0238_0253 0.763 0.70
0058_0062 0.762 0.70
0043_0211 0.759 0.70
0239_0254 0.757 0.69
0230_0235 0.757 0.69
0109_0112 0.752 0.69
0237_0254 0.748 0.68
0114_0117 0.747 0.68
0201_0205 0.746 0.68
0260_0263 0.744 0.68
0154_0159 0.740 0.67
0049_0130 0.735 0.66
0043_0124 0.735 0.66
0076_0080 0.733 0.66
0092_0189 0.733 0.66
0110_0147 0.733 0.66
0211_0265 0.732 0.66
0097_0100 0.732 0.66
0058_0068 0.728 0.65
0129_0147 0.727 0.65
0081_0182 0.725 0.65
0188_0219 0.724 0.64
0094_0097 0.724 0.64
0119_0122 0.720 0.64
0172_0182 0.718 0.64
0265_0269 0.717 0.63
0149_0186 0.717 0.63
0070_0074 0.716 0.63
0267_0272 0.714 0.63
0156_0181 0.707 0.62
0129_0215 0.707 0.62
0097_0101 0.706 0.62
0046_0225 0.705 0.61
0133_0150 0.703 0.61
0190_0219 0.703 0.61
0200_0225 0.702 0.61
0221_0226 0.701 0.61
0266_0270 0.700 0.61
0093_0096 0.699 0.60
0050_0130 0.699 0.60
0142_0199 0.698 0.60
0052_0130 0.696 0.60
0212_0215 0.694 0.60
0110_0129 0.691 0.59
0147_0219 0.691 0.59
0032_0036 0.690 0.59
0252_0268 0.690 0.59
0118_0264 0.687 0.58
0188_0192 0.684 0.58
0204_0236 0.683 0.58
0212_0236 0.682 0.58
0150_0187 0.681 0.57
0268_0271 0.679 0.57
0046_0222 0.678 0.57
0128_0132 0.677 0.57
0109_0257 0.675 0.56
0055_0106 0.675 0.56
0227_0231 0.673 0.56
0041_0209 0.671 0.56
0153_0164 0.670 0.56
0037_0209 0.670 0.56
0185_0189 0.670 0.56
0089_0182 0.667 0.55
0133_0136 0.663 0.54
0146_0200 0.663 0.54
0247_0250 0.662 0.54
0113_0124 0.662 0.54
0081_0085 0.661 0.54
0140_0143 0.661 0.54
0044_0203 0.660 0.54
0089_0170 0.659 0.54
0045_0124 0.658 0.54
0070_0080 0.657 0.53
0262_0266 0.656 0.53
0070_0075 0.656 0.53
0049_0059 0.655 0.53
0101_0104 0.655 0.53
0037_0040 0.654 0.53
0152_0163 0.654 0.53
0095_0189 0.649 0.52
0133_0187 0.648 0.52
0043_0209 0.648 0.52
0230_0234 0.646 0.52
0157_0181 0.645 0.51
0241_0256 0.645 0.51
0203_0206 0.640 0.50
0064_0068 0.640 0.50
0052_0060 0.640 0.50
0126_0140 0.639 0.50
0113_0213 0.636 0.50
0049_0129 0.633 0.49
0163_0167 0.630 0.49
0063_0068 0.628 0.48
0051_0126 0.626 0.48
0122_0269 0.624 0.48
0091_0094 0.623 0.48
0088_0095 0.619 0.47
0149_0172 0.617 0.47
0253_0256 0.616 0.46
0052_0132 0.614 0.46
0032_0035 0.614 0.46
0078_0189 0.613 0.46
0051_0213 0.612 0.46
0036_0235 0.612 0.46
0049_0110 0.611 0.46
0104_0133 0.611 0.46
0230_0233 0.611 0.46
0221_0224 0.611 0.46
0201_0225 0.609 0.45
0099_0133 0.609 0.45
0119_0265 0.608 0.45
0053_0062 0.606 0.45
0257_0263 0.604 0.44
0159_0162 0.601 0.44
0236_0251 0.601 0.44
0054_0107 0.599 0.43
0231_0248 0.597 0.43
0060_0065 0.596 0.43
0060_0066 0.596 0.43
0207_0210 0.595 0.43
0107_0110 0.595 0.43
0076_0081 0.594 0.43
0184_0190 0.592 0.42
0130_0147 0.592 0.42
0061_0129 0.591 0.42
0074_0080 0.590 0.42
0044_0225 0.590 0.42
0076_0092 0.588 0.42
0072_0075 0.587 0.41
0049_0061 0.584 0.41
0049_0219 0.583 0.41
0031_0034 0.583 0.41
0173_0182 0.583 0.41
0129_0132 0.581 0.40
0041_0264 0.580 0.40
0095_0187 0.579 0.40
0099_0172 0.578 0.40
0058_0061 0.578 0.40
0084_0090 0.577 0.40
0081_0089 0.575 0.39
0051_0107 0.575 0.39
0243_0253 0.575 0.39
0088_0096 0.574 0.39
0164_0167 0.573 0.39
0072_0091 0.572 0.39
0120_0270 0.570 0.39
0118_0202 0.570 0.39
0220_0227 0.570 0.39
0261_0265 0.567 0.38
0074_0084 0.567 0.38
0059_0065 0.566 0.38
0078_0192 0.566 0.38
0037_0269 0.565 0.38
0104_0187 0.563 0.38
0241_0255 0.562 0.37
0053_0217 0.560 0.37
0127_0203 0.560 0.37
0161_0195 0.557 0.37
0222_0225 0.555 0.36
0238_0251 0.554 0.36
0040_0122 0.554 0.36
Local Interactions:
i_j Score Prob
0071_0073 3.280 1.00
0234_0235 2.874 1.00
0253_0255 2.251 1.00
0057_0058 1.723 1.00
0257_0259 1.660 1.00
0149_0151 1.620 1.00
0084_0086 1.535 1.00
0241_0242 1.357 0.99
0210_0212 1.348 0.99
0124_0126 1.311 0.99
0049_0050 1.297 0.99
0270_0271 1.286 0.99
0045_0047 1.259 0.99
0194_0195 1.243 0.98
0223_0224 1.236 0.98
0221_0223 1.222 0.98
0103_0104 1.182 0.98
0244_0245 1.141 0.97
0088_0089 1.135 0.97
0065_0066 1.126 0.97
0160_0162 1.124 0.97
0077_0078 1.123 0.97
0091_0092 1.121 0.97
0078_0079 1.108 0.96
0174_0175 1.108 0.96
0171_0172 1.104 0.96
0077_0079 1.099 0.96
0256_0257 1.094 0.96
0262_0263 1.091 0.96
0142_0144 1.058 0.95
0039_0040 1.034 0.94
0189_0190 1.017 0.93
0071_0072 0.999 0.92
0076_0077 0.996 0.92
0261_0263 0.986 0.92
0068_0069 0.972 0.91
0101_0102 0.969 0.91
0211_0213 0.968 0.91
0246_0247 0.965 0.90
0226_0227 0.947 0.89
0238_0240 0.943 0.89
0050_0052 0.938 0.89
0094_0095 0.938 0.89
0219_0221 0.936 0.89
0118_0119 0.926 0.88
0065_0067 0.923 0.88
0048_0049 0.914 0.87
0040_0041 0.908 0.87
0252_0254 0.897 0.86
0102_0103 0.895 0.85
0270_0272 0.894 0.85
0070_0071 0.891 0.85
0042_0043 0.889 0.85
0224_0226 0.876 0.84
0038_0039 0.861 0.82
0268_0269 0.860 0.82
0072_0073 0.858 0.82
0269_0270 0.855 0.82
0254_0256 0.854 0.82
0242_0243 0.850 0.81
0063_0064 0.838 0.80
0100_0101 0.837 0.80
0124_0125 0.831 0.79
0074_0075 0.830 0.79
0061_0062 0.828 0.79
0060_0061 0.825 0.78
0167_0168 0.822 0.78
0098_0099 0.818 0.78
0221_0222 0.817 0.77
0086_0087 0.815 0.77
0255_0256 0.815 0.77
0156_0157 0.814 0.77
0166_0167 0.809 0.77
0082_0083 0.807 0.76
0227_0228 0.799 0.75
0123_0125 0.796 0.75
0054_0055 0.796 0.75
0187_0189 0.792 0.74
0125_0127 0.787 0.74
0240_0242 0.787 0.74
0267_0269 0.786 0.74
0271_0272 0.785 0.73
0035_0036 0.765 0.71
0222_0223 0.759 0.70
0263_0264 0.752 0.69
0152_0154 0.747 0.68
0250_0251 0.736 0.66
0068_0070 0.736 0.66
0031_0032 0.733 0.66
0122_0123 0.731 0.66
0190_0192 0.730 0.65
0165_0166 0.728 0.65
0123_0124 0.719 0.64
0032_0034 0.715 0.63
0142_0143 0.715 0.63
0232_0234 0.702 0.61
0040_0042 0.697 0.60
0075_0076 0.697 0.60
0205_0206 0.696 0.60
0200_0201 0.696 0.60
0097_0098 0.696 0.60
0066_0067 0.696 0.60
0037_0038 0.694 0.60
0249_0250 0.692 0.59
0179_0181 0.691 0.59
0048_0050 0.688 0.59
0092_0093 0.681 0.57
0062_0064 0.680 0.57
0092_0094 0.680 0.57
0130_0132 0.676 0.57
0073_0074 0.676 0.57
0139_0140 0.671 0.56
0041_0042 0.668 0.55
0220_0221 0.662 0.54
0243_0244 0.660 0.54
0164_0165 0.659 0.54
0039_0041 0.658 0.54
0165_0167 0.655 0.53
0129_0130 0.654 0.53
0260_0261 0.652 0.53
0154_0156 0.647 0.52
0032_0033 0.645 0.51
0172_0174 0.644 0.51
0113_0114 0.644 0.51
0076_0078 0.643 0.51
0197_0198 0.640 0.50
0141_0142 0.638 0.50
0175_0177 0.637 0.50
0107_0109 0.636 0.50
0151_0152 0.634 0.49
0097_0099 0.631 0.49
0036_0038 0.631 0.49
0268_0270 0.624 0.48
0120_0122 0.623 0.48
0121_0122 0.621 0.47
0159_0160 0.620 0.47
0169_0171 0.617 0.47
0184_0185 0.617 0.47
0080_0081 0.615 0.46
0120_0121 0.615 0.46
0089_0090 0.614 0.46
0072_0074 0.609 0.45
0149_0150 0.607 0.45
0244_0246 0.606 0.45
0193_0194 0.605 0.45
0062_0063 0.602 0.44
0247_0249 0.602 0.44
0036_0037 0.601 0.44
0179_0180 0.600 0.44
0239_0241 0.600 0.44
0164_0166 0.599 0.43
0236_0238 0.598 0.43
0111_0112 0.594 0.43
0188_0190 0.594 0.43
0185_0187 0.585 0.41
0084_0085 0.584 0.41
0157_0159 0.583 0.41
0033_0035 0.581 0.40
0202_0203 0.581 0.40
0224_0225 0.577 0.40
0059_0061 0.572 0.39
0245_0246 0.570 0.39
0190_0191 0.567 0.38
0191_0192 0.566 0.38
0108_0109 0.562 0.37
0169_0170 0.558 0.37
0248_0249 0.558 0.37
0251_0252 0.557 0.37
0083_0084 0.556 0.36
0247_0248 0.556 0.36
See all coupling residues
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Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M L S R R ...
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