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Instructions
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Coupling matrix for [E:0054] and [F:0057]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.6 -0.3 -0.3 0.5 0 -0.1 -0.2 -0.2 0.3 -0.1 -0.1 0 0.1 -0.1 -0.2 0.1 -0.3 0.4 0.1 -0.2
F -0.1 0 0 -0.1 -0.1 0 0 0 0.1 -0.3 0.6 -0.3 -0.1 0.5 -0.1 -0.3 -0.1 -0.1 0 0
I -0.6 -0.1 -0.1 0.1 -0.3 -0.1 -0.1 -0.1 0.2 0.3 0.5 0.2 -0.1 0 0 0.1 0.1 0.2 -0.1 -0.1
L -0.2 -0.1 -0.2 -0.3 0 -0.1 -0.1 -0.1 0.3 0.5 0.4 0.2 0 0.5 0.8 0.2 -0.5 -0.5 -0.2 -0.1
V 0.2 -0.1 -0.1 -0.2 -0.1 0 0 0 0.4 0.1 0.2 -0.5 -0.2 -0.1 -0.2 0.2 0 0 -0.1 0
M -0.1 0 0 -0.1 -0.1 0 0 0 0.6 0.3 0.5 0.3 -0.2 0 0 -0.4 -0.2 -0.2 -0.1 0
W -0.2 0 0 0 0 0 0 0 -0.2 0.4 0.1 0 0 -0.1 -0.1 -0.1 -0.1 0 0 0
Y -0.4 0 0 -0.1 -0.1 0 0 0 0 0.3 -0.4 -0.1 -0.1 0.3 -0.3 0.6 -0.2 0.3 0 0
D 0.4 0.4 0.1 0 -0.2 -0.1 0 -0.1 -0.6 -0.4 0.6 0.2 0.6 -0.1 0 0.3 -0.1 0 -0.1 -0.1
E 0.2 0.4 -0.3 0.1 0.2 -0.3 -0.1 0.1 -1 -0.6 0.3 0.1 -0.4 0.5 0 0.4 0.2 0.3 -0.4 0.2
K 0.4 -0.1 0 -0.4 0.4 0.7 -0.1 -0.1 0.6 0.4 -0.4 -0.8 -0.1 0.1 0.2 0 0.7 -0.4 -0.2 -0.1
R 0.8 -0.2 -0.3 -0.5 -0.2 -0.2 -0.1 -0.1 0.5 0.2 -0.1 0 -0.2 -0.7 0.1 -0.3 0.3 0.9 0.3 -0.1
H -0.3 0 -0.1 -0.1 -0.1 0 0 0 -0.3 0.2 -0.6 0.3 0.1 -0.3 0.7 0.3 -0.2 0.2 0 0
N 0.1 0 0.4 0.3 -0.1 0 0 0 -0.1 -0.2 0.7 -0.5 -0.2 0.6 -0.3 -0.1 0 -0.2 0 0
Q 0.2 -0.2 0.4 1.1 0.4 -0.2 -0.1 -0.1 -0.2 -0.1 -0.4 0.2 0.7 -0.4 0.4 0.3 0.4 -0.6 -0.2 -0.1
S -0.2 -0.1 -0.1 -0.1 0.2 -0.1 0 -0.1 0.2 -0.2 -0.3 0.2 -0.4 -0.1 0.2 0.1 0.1 0.6 -0.1 -0.1
T -0.2 -0.1 -0.1 -0.3 -0.2 -0.1 -0.1 0.1 0 0.2 -0.1 0.4 0.2 0.1 -0.1 -0.1 0.7 -0.5 0.3 -0.1
G 0.4 0 0.2 -0.1 -0.1 0 0 0 -0.5 0.3 0 0.7 -0.1 -0.2 -0.5 -0.4 -0.2 -0.1 0.4 0
P -0.1 0 0 0 0 0 0 0 -0.1 -0.2 -0.1 -0.1 0 0 0.1 -0.1 0 0 0 0
C 0.1 0 0 0 0 0 0 0 0 0 -0.3 0.1 0 -0.1 0.3 -0.1 -0.1 -0.1 0 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0054 1.3 -1 -0.2 0 -0.3 -0.6 -0.9 -0.3 0.8 1.5 1.1 0.4 -0.1 -0.2 1.3 0.2 0.5 -0.3 -1.3 -1
0057 1.5 -1.4 -1.2 -0.6 -0.8 -1.5 -1.8 -1.6 1.1 1.8 2 1.4 -0.2 0.5 1.3 1.1 0.5 0.2 -1.2 -1.6
Select residue pair below:
i_j Score Prob
0056_0085 3.649 1.00
0094_0119 2.672 1.00
0080_0105 2.554 1.00
0050_0053 2.461 1.00
0093_0122 2.444 1.00
0029_0058 2.384 1.00
0028_0055 2.311 1.00
0030_0034 2.282 1.00
0072_0075 2.167 1.00
0049_0078 2.129 1.00
0097_0107 2.099 1.00
0053_0057 1.965 1.00
0043_0049 1.962 1.00
0098_0123 1.958 1.00
0111_0128 1.950 1.00
0077_0099 1.921 1.00
0120_0128 1.892 1.00
0025_0058 1.835 1.00
0077_0081 1.826 1.00
0165_0169 1.803 1.00
0074_0078 1.801 1.00
0020_0023 1.800 1.00
0121_0151 1.760 1.00
0117_0151 1.757 1.00
0070_0087 1.738 1.00
0140_0144 1.735 1.00
0025_0054 1.733 1.00
0075_0078 1.718 1.00
0052_0067 1.692 1.00
0099_0103 1.691 1.00
0087_0100 1.685 1.00
0190_0194 1.665 1.00
0100_0107 1.651 1.00
0079_0084 1.651 1.00
0091_0118 1.645 1.00
0041_0055 1.634 1.00
0032_0063 1.634 1.00
0101_0126 1.620 1.00
0092_0123 1.617 1.00
0188_0191 1.603 1.00
0113_0116 1.601 1.00
0089_0107 1.593 1.00
0092_0097 1.588 1.00
0047_0050 1.550 1.00
0111_0117 1.547 1.00
0033_0190 1.531 1.00
0141_0172 1.525 1.00
0021_0047 1.515 1.00
0029_0033 1.504 1.00
0136_0140 1.497 1.00
0076_0087 1.457 1.00
0013_0154 1.450 1.00
0121_0150 1.435 1.00
0186_0192 1.414 1.00
0076_0099 1.409 1.00
0066_0086 1.409 1.00
0077_0103 1.405 0.99
0095_0122 1.392 0.99
0016_0039 1.361 0.99
0114_0144 1.357 0.99
0112_0136 1.342 0.99
0092_0111 1.339 0.99
0099_0102 1.336 0.99
0134_0139 1.311 0.99
0191_0195 1.300 0.99
0160_0163 1.289 0.99
0028_0039 1.285 0.99
0188_0192 1.283 0.99
0130_0153 1.261 0.99
0071_0075 1.254 0.99
0043_0079 1.249 0.99
0133_0159 1.246 0.98
0118_0148 1.243 0.98
0052_0065 1.232 0.98
0094_0123 1.229 0.98
0194_0198 1.228 0.98
0076_0096 1.215 0.98
0050_0054 1.208 0.98
0089_0109 1.203 0.98
0005_0008 1.202 0.98
0130_0136 1.184 0.98
0112_0140 1.163 0.97
0094_0098 1.155 0.97
0088_0108 1.153 0.97
0117_0144 1.149 0.97
0164_0175 1.148 0.97
0098_0102 1.147 0.97
0135_0140 1.144 0.97
0008_0152 1.126 0.97
0155_0172 1.125 0.97
0080_0103 1.100 0.96
0053_0081 1.095 0.96
0187_0191 1.084 0.96
0076_0100 1.067 0.95
0134_0143 1.065 0.95
0025_0029 1.065 0.95
0163_0166 1.062 0.95
0166_0169 1.056 0.95
0087_0105 1.052 0.95
0054_0058 1.048 0.94
0073_0095 1.038 0.94
0032_0037 1.036 0.94
0029_0059 1.036 0.94
0117_0148 1.033 0.94
0018_0051 1.029 0.94
0095_0098 1.028 0.94
0107_0125 1.027 0.94
0134_0167 1.024 0.93
0074_0077 1.024 0.93
0073_0099 1.013 0.93
0034_0190 1.004 0.93
0015_0156 0.996 0.92
0005_0009 0.991 0.92
0022_0054 0.986 0.92
0032_0059 0.982 0.91
0019_0184 0.977 0.91
0064_0085 0.969 0.91
0154_0174 0.965 0.90
0078_0081 0.963 0.90
0010_0037 0.959 0.90
0038_0086 0.956 0.90
0067_0079 0.956 0.90
0049_0079 0.920 0.87
0097_0125 0.919 0.87
0079_0087 0.915 0.87
0139_0166 0.914 0.87
0054_0057 0.911 0.87
0021_0051 0.898 0.86
0080_0099 0.885 0.85
0056_0082 0.884 0.84
0130_0140 0.880 0.84
0091_0096 0.874 0.84
0115_0119 0.871 0.83
0186_0189 0.871 0.83
0044_0149 0.866 0.83
0004_0127 0.865 0.83
0006_0009 0.865 0.83
0079_0082 0.863 0.83
0111_0120 0.862 0.82
0010_0038 0.859 0.82
0155_0173 0.858 0.82
0156_0176 0.857 0.82
0112_0144 0.853 0.81
0038_0064 0.853 0.81
0093_0118 0.845 0.81
0015_0042 0.844 0.81
0025_0055 0.843 0.80
0015_0088 0.842 0.80
0192_0195 0.842 0.80
0197_0200 0.836 0.80
0067_0087 0.831 0.79
0161_0195 0.820 0.78
0023_0026 0.820 0.78
0139_0143 0.817 0.77
0012_0036 0.812 0.77
0137_0140 0.803 0.76
0081_0103 0.802 0.76
0026_0029 0.798 0.75
0117_0128 0.797 0.75
0077_0080 0.793 0.74
0157_0178 0.791 0.74
0183_0186 0.791 0.74
0031_0182 0.786 0.74
0041_0052 0.785 0.73
0025_0051 0.780 0.73
0069_0090 0.777 0.72
0128_0151 0.774 0.72
0010_0036 0.773 0.72
0197_0201 0.772 0.72
0089_0100 0.770 0.71
0009_0064 0.770 0.71
0021_0050 0.767 0.71
0141_0153 0.765 0.71
0119_0123 0.764 0.71
0135_0143 0.759 0.70
0156_0177 0.758 0.70
0097_0123 0.755 0.69
0018_0027 0.749 0.68
0070_0076 0.747 0.68
0160_0180 0.747 0.68
0053_0082 0.747 0.68
0047_0051 0.747 0.68
0073_0096 0.746 0.68
0071_0150 0.739 0.67
0164_0168 0.738 0.67
0049_0053 0.738 0.67
0024_0055 0.738 0.67
0049_0082 0.738 0.67
0018_0044 0.732 0.66
0138_0170 0.730 0.65
0092_0120 0.727 0.65
0014_0044 0.721 0.64
0036_0181 0.721 0.64
0120_0123 0.717 0.63
0187_0190 0.713 0.63
0088_0110 0.712 0.63
0108_0127 0.711 0.62
0072_0122 0.709 0.62
0044_0156 0.708 0.62
0027_0182 0.704 0.61
0018_0023 0.704 0.61
0117_0153 0.703 0.61
0027_0189 0.700 0.61
0162_0166 0.699 0.60
0021_0054 0.696 0.60
0161_0164 0.695 0.60
0093_0096 0.695 0.60
0100_0105 0.688 0.59
0092_0119 0.687 0.58
0073_0077 0.684 0.58
0002_0005 0.682 0.58
0053_0056 0.679 0.57
0109_0125 0.678 0.57
0042_0146 0.677 0.57
0181_0193 0.677 0.57
0195_0198 0.676 0.57
0145_0173 0.674 0.56
0009_0037 0.670 0.56
0004_0152 0.669 0.55
0017_0184 0.669 0.55
0028_0059 0.668 0.55
0056_0060 0.663 0.54
0127_0174 0.658 0.54
0159_0179 0.658 0.54
0004_0007 0.656 0.53
0191_0194 0.656 0.53
0015_0044 0.654 0.53
0193_0197 0.653 0.53
0024_0051 0.652 0.53
0114_0148 0.651 0.52
0189_0193 0.649 0.52
0055_0065 0.649 0.52
0045_0051 0.647 0.52
0074_0102 0.643 0.51
0164_0200 0.643 0.51
0143_0156 0.639 0.50
0043_0075 0.634 0.49
0125_0128 0.633 0.49
0026_0031 0.632 0.49
0148_0176 0.629 0.49
0037_0064 0.628 0.48
0016_0182 0.627 0.48
0021_0024 0.621 0.47
0076_0105 0.620 0.47
0040_0129 0.618 0.47
0006_0010 0.617 0.47
0091_0122 0.614 0.46
0181_0192 0.612 0.46
0092_0107 0.610 0.45
0084_0087 0.608 0.45
0183_0192 0.606 0.45
0146_0172 0.605 0.45
0185_0188 0.602 0.44
0168_0175 0.600 0.44
0028_0065 0.599 0.43
0107_0126 0.598 0.43
0130_0141 0.597 0.43
0102_0122 0.596 0.43
0041_0048 0.588 0.42
0029_0062 0.588 0.42
0139_0142 0.587 0.41
0176_0181 0.586 0.41
0042_0045 0.584 0.41
0030_0190 0.578 0.40
0192_0196 0.578 0.40
0016_0024 0.575 0.39
0162_0195 0.574 0.39
0089_0106 0.572 0.39
0160_0196 0.572 0.39
0117_0130 0.571 0.39
0188_0202 0.570 0.39
0076_0103 0.568 0.38
0025_0059 0.567 0.38
0039_0063 0.567 0.38
0198_0202 0.565 0.38
0008_0173 0.563 0.38
0167_0183 0.562 0.37
0111_0153 0.559 0.37
0039_0055 0.558 0.37
0004_0126 0.553 0.36
0159_0167 0.553 0.36
0071_0121 0.551 0.36
0042_0147 0.548 0.35
0059_0062 0.546 0.35
0081_0098 0.544 0.35
0014_0017 0.543 0.34
0032_0039 0.542 0.34
0145_0153 0.540 0.34
0100_0103 0.537 0.33
0019_0023 0.537 0.33
0019_0024 0.535 0.33
0116_0148 0.535 0.33
0108_0154 0.535 0.33
0006_0064 0.534 0.33
0064_0086 0.533 0.33
0011_0168 0.532 0.33
0069_0129 0.531 0.33
0052_0082 0.530 0.32
0007_0127 0.530 0.32
0069_0156 0.527 0.32
0148_0151 0.527 0.32
Local Interactions:
i_j Score Prob
0020_0022 2.390 1.00
0146_0147 2.090 1.00
0186_0188 2.081 1.00
0060_0061 1.949 1.00
0160_0162 1.840 1.00
0112_0114 1.655 1.00
0061_0062 1.602 1.00
0057_0058 1.395 0.99
0181_0182 1.273 0.99
0091_0093 1.239 0.98
0150_0151 1.200 0.98
0183_0185 1.183 0.98
0045_0046 1.177 0.98
0160_0161 1.172 0.98
0076_0077 1.161 0.97
0126_0127 1.123 0.97
0010_0011 1.098 0.96
0138_0139 1.078 0.95
0112_0113 1.076 0.95
0163_0165 1.034 0.94
0151_0152 1.023 0.93
0155_0156 1.021 0.93
0165_0166 1.008 0.93
0019_0020 0.977 0.91
0134_0135 0.973 0.91
0200_0201 0.972 0.91
0164_0165 0.971 0.91
0082_0084 0.946 0.89
0072_0073 0.933 0.88
0106_0107 0.931 0.88
0170_0172 0.922 0.88
0089_0091 0.910 0.87
0102_0103 0.894 0.85
0161_0162 0.833 0.79
0058_0059 0.825 0.78
0072_0074 0.822 0.78
0199_0200 0.817 0.77
0184_0185 0.814 0.77
0046_0047 0.809 0.77
0037_0038 0.801 0.76
0033_0034 0.799 0.75
0038_0039 0.796 0.75
0197_0199 0.787 0.74
0044_0045 0.784 0.73
0053_0054 0.775 0.72
0197_0198 0.773 0.72
0175_0177 0.764 0.71
0168_0169 0.757 0.69
0105_0106 0.755 0.69
0187_0188 0.750 0.68
0149_0150 0.737 0.67
0054_0055 0.737 0.67
0008_0009 0.737 0.67
0074_0075 0.735 0.66
0036_0037 0.727 0.65
0073_0074 0.707 0.62
0004_0005 0.707 0.62
0103_0104 0.706 0.62
0025_0026 0.700 0.61
0094_0095 0.696 0.60
0093_0095 0.674 0.56
0198_0199 0.665 0.55
0190_0191 0.663 0.54
0024_0026 0.655 0.53
0196_0197 0.649 0.52
0093_0094 0.645 0.51
0043_0044 0.643 0.51
0005_0006 0.636 0.50
0171_0172 0.635 0.50
0034_0035 0.632 0.49
0183_0184 0.630 0.49
0016_0017 0.628 0.48
0194_0195 0.622 0.47
0106_0108 0.620 0.47
0059_0060 0.615 0.46
0027_0028 0.614 0.46
0009_0010 0.611 0.46
0007_0008 0.605 0.45
0021_0022 0.602 0.44
0030_0031 0.590 0.42
0063_0065 0.587 0.41
0003_0004 0.586 0.41
0178_0179 0.576 0.40
0068_0069 0.572 0.39
0145_0146 0.568 0.38
0162_0163 0.565 0.38
0111_0112 0.555 0.36
0002_0003 0.551 0.36
0018_0019 0.550 0.35
0071_0072 0.549 0.35
0109_0111 0.543 0.34
0012_0013 0.541 0.34
0135_0136 0.540 0.34
0191_0192 0.539 0.34
0182_0183 0.537 0.33
0147_0148 0.536 0.33
0080_0081 0.534 0.33
0201_0202 0.528 0.32
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M K M E E ...

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