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4HE8HPDBIDCHAINSEQUENCE Return to Main Page
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Coupling matrix for [N:0183] and [V:0186]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.1 0.3 0.4 -0.2 0.3 0.1 -0.1 -0.3 -0.1 -0.1 -0.1 0.4 -0.1 -0.2 -0.1 -0.1 -0.3 0 0.1 -0.2
F -0.1 0.6 -0.2 0 -0.6 0.1 -0.1 0.4 -0.1 0 0.5 -0.1 -0.1 0.4 -0.2 -0.6 -0.6 0.5 -0.3 0.8
I -0.3 -0.1 -0.1 -0.5 -0.1 -0.1 -0.1 0.4 0.3 0.8 -0.2 0 -0.1 0.8 -0.2 -0.5 0.2 0 -0.3 -0.2
L -0.2 0 0.1 -0.2 -0.9 0.3 -0.1 0.5 0.2 0.2 0.2 -0.1 -0.1 0 -0.2 0.1 0.1 0.1 0 0.1
V 0 -0.1 -0.1 -0.1 0.3 0.5 -0.1 -0.2 -0.1 -0.2 -0.4 0.3 -0.1 0.4 -0.2 0.4 -0.1 0.5 -0.2 -0.4
M -0.6 0.3 0 0 -0.4 0.1 0 0.7 -0.1 -0.2 -0.3 -0.1 -0.1 0.2 -0.1 0.5 0.3 -0.3 0.5 -0.2
W -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0 0 0 0 0 0 0 -0.1 0 -0.1 -0.1 0.4 0 0
Y -0.1 0.2 0.1 0.5 -0.4 -0.1 -0.1 -0.4 -0.1 -0.2 -0.3 -0.1 0.2 0.6 0.3 0.2 -0.1 -0.2 -0.2 0.1
D 0.4 -0.1 0 0.5 0 -0.3 0 -0.2 -0.1 -0.1 -0.2 -0.1 -0.1 -0.3 -0.1 0 -0.2 0.2 -0.1 0.3
E 0.3 -0.6 -0.2 -0.3 0 -0.5 -0.1 -0.1 -0.1 0.1 0.6 -0.1 -0.1 -0.4 -0.1 1 0.4 -0.2 0.2 -0.3
K -0.1 -0.2 -0.3 0.1 -0.3 1.1 0.2 -0.5 -0.1 0.1 0.1 -0.1 -0.1 0.1 -0.2 -0.1 0.2 0 -0.2 0.5
R 0.7 -0.4 -0.4 -0.4 0.3 -0.4 0 -0.1 0 -0.1 -0.1 0 -0.1 0 0.8 -0.5 0.5 -0.3 -0.1 -0.2
H -0.1 0.9 0 0.4 -0.3 0.3 0 -0.1 0 -0.1 -0.1 0 0 -0.1 -0.1 -0.3 -0.1 -0.2 -0.1 -0.1
N 0.3 0.3 0.6 -0.1 0.5 -0.1 -0.1 0.3 -0.1 0.1 0 -0.1 -0.1 -0.2 -0.2 -0.6 0.2 -0.5 0.4 0
Q -0.5 0.2 0.5 -0.2 -0.3 0.1 -0.1 -0.4 -0.1 -0.3 0.7 -0.1 -0.1 0.2 0.2 0.8 0.9 -0.4 -0.2 0
S 0.2 0 0.3 -0.1 0.7 0 0.2 0 -0.3 -0.5 -0.2 -0.2 0.3 -0.2 0.1 0.2 -0.4 -0.1 0.1 0.8
T 0.3 -0.1 0 0.2 0.7 0 -0.1 0.4 -0.2 0.2 0.1 -0.1 0 -0.4 -0.2 -0.4 0.2 -0.2 -0.2 -0.3
G 0.4 -0.4 -0.3 -0.1 0.6 -0.2 0.4 -0.5 -0.1 0.1 -0.2 -0.1 0.3 -0.7 -0.1 0.7 -0.6 1 0.7 -0.4
P 0 0 0.1 0.2 0.3 0.1 0 -0.1 -0.1 -0.1 -0.1 0 0 0.5 -0.1 -0.3 0 -0.2 -0.1 -0.1
C -0.1 0.3 0.2 0.3 -0.4 -0.3 0 -0.1 0 0 -0.1 0 0 -0.1 0 -0.2 -0.1 0.3 0 0
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0183 0.1 0.5 -0.1 0.1 0.2 -0.4 -1.1 0.1 0.1 0.3 0.2 -0.9 -0.5 0.8 0.2 1.3 -0.1 0.3 -0.1 -0.8
0186 0.3 0.9 0.5 0.8 -0.7 0.8 -0.7 0 -0.5 -0.1 -0.4 -0.8 -0.7 0.5 -0.8 0.5 0.5 0.4 -0.1 -0.3
Select residue pair below:
i_j Score Prob
0179_0184 3.910 1.00
0032_0059 3.037 1.00
0203_0259 3.010 1.00
0257_0279 2.842 1.00
0039_0295 2.841 1.00
0264_0286 2.751 1.00
0207_0289 2.704 1.00
0260_0279 2.460 1.00
0148_0234 2.362 1.00
0211_0293 2.289 1.00
0184_0187 2.289 1.00
0093_0250 2.211 1.00
0224_0228 2.063 1.00
0038_0288 2.033 1.00
0187_0190 1.996 1.00
0257_0283 1.989 1.00
0253_0287 1.960 1.00
0042_0295 1.915 1.00
0071_0240 1.835 1.00
0269_0278 1.805 1.00
0060_0063 1.781 1.00
0089_0247 1.775 1.00
0095_0124 1.772 1.00
0202_0263 1.763 1.00
0207_0211 1.728 1.00
0093_0251 1.725 1.00
0175_0325 1.661 1.00
0140_0152 1.657 1.00
0081_0138 1.638 1.00
0194_0282 1.621 1.00
0188_0195 1.610 1.00
0090_0243 1.604 1.00
0206_0259 1.554 1.00
0242_0246 1.526 1.00
0275_0278 1.519 1.00
0221_0305 1.514 1.00
0182_0258 1.502 1.00
0196_0264 1.498 1.00
0196_0203 1.492 1.00
0208_0313 1.487 1.00
0099_0124 1.486 1.00
0037_0069 1.486 1.00
0174_0180 1.474 1.00
0018_0022 1.451 1.00
0145_0148 1.446 1.00
0210_0255 1.441 1.00
0096_0254 1.441 1.00
0214_0290 1.441 1.00
0202_0320 1.427 1.00
0288_0292 1.413 1.00
0230_0233 1.411 1.00
0035_0216 1.406 0.99
0024_0250 1.386 0.99
0166_0309 1.367 0.99
0028_0246 1.361 0.99
0241_0245 1.346 0.99
0169_0205 1.331 0.99
0256_0286 1.315 0.99
0124_0128 1.315 0.99
0089_0135 1.311 0.99
0172_0321 1.297 0.99
0302_0306 1.297 0.99
0177_0195 1.283 0.99
0040_0046 1.281 0.99
0028_0250 1.265 0.99
0217_0297 1.265 0.99
0292_0296 1.257 0.99
0085_0139 1.255 0.99
0252_0287 1.249 0.99
0155_0222 1.244 0.98
0212_0219 1.241 0.98
0168_0318 1.238 0.98
0169_0317 1.237 0.98
0058_0062 1.234 0.98
0199_0324 1.233 0.98
0066_0242 1.232 0.98
0098_0124 1.230 0.98
0041_0046 1.228 0.98
0320_0324 1.227 0.98
0177_0185 1.225 0.98
0165_0209 1.223 0.98
0205_0208 1.223 0.98
0030_0059 1.214 0.98
0042_0292 1.214 0.98
0126_0167 1.211 0.98
0043_0235 1.210 0.98
0083_0240 1.207 0.98
0035_0294 1.206 0.98
0161_0306 1.202 0.98
0186_0266 1.202 0.98
0172_0202 1.201 0.98
0077_0082 1.197 0.98
0172_0317 1.197 0.98
0260_0264 1.197 0.98
0088_0092 1.194 0.98
0064_0068 1.188 0.98
0286_0289 1.187 0.98
0259_0286 1.186 0.98
0038_0042 1.183 0.98
0067_0242 1.177 0.98
0046_0049 1.176 0.98
0299_0303 1.170 0.97
0210_0259 1.168 0.97
0189_0265 1.150 0.97
0034_0288 1.149 0.97
0034_0291 1.145 0.97
0138_0142 1.130 0.97
0179_0185 1.130 0.97
0065_0069 1.128 0.97
0158_0215 1.125 0.97
0265_0282 1.123 0.97
0097_0254 1.122 0.97
0257_0261 1.118 0.96
0074_0077 1.116 0.96
0214_0255 1.111 0.96
0165_0314 1.110 0.96
0027_0284 1.109 0.96
0026_0060 1.107 0.96
0027_0253 1.104 0.96
0222_0232 1.100 0.96
0031_0287 1.099 0.96
0118_0124 1.098 0.96
0030_0060 1.088 0.96
0194_0265 1.084 0.96
0155_0224 1.082 0.96
0134_0302 1.079 0.95
0035_0291 1.079 0.95
0063_0246 1.076 0.95
0225_0229 1.075 0.95
0203_0263 1.074 0.95
0281_0285 1.072 0.95
0274_0277 1.069 0.95
0206_0255 1.067 0.95
0186_0267 1.067 0.95
0194_0266 1.067 0.95
0285_0289 1.065 0.95
0058_0065 1.063 0.95
0264_0282 1.063 0.95
0036_0062 1.058 0.95
0261_0266 1.047 0.94
0158_0305 1.045 0.94
0215_0248 1.043 0.94
0233_0241 1.042 0.94
0139_0142 1.040 0.94
0090_0247 1.039 0.94
0043_0048 1.037 0.94
0036_0045 1.034 0.94
0213_0216 1.033 0.94
0193_0197 1.031 0.94
0022_0025 1.027 0.94
0129_0132 1.025 0.93
0181_0184 1.024 0.93
0137_0156 1.021 0.93
0308_0313 1.021 0.93
0177_0188 1.020 0.93
0066_0252 1.013 0.93
0224_0232 1.010 0.93
0085_0135 1.010 0.93
0117_0121 1.007 0.93
0117_0179 1.006 0.93
0048_0065 1.006 0.93
0064_0067 1.004 0.93
0025_0029 1.004 0.93
0121_0181 1.000 0.92
0258_0262 0.994 0.92
0221_0300 0.993 0.92
0039_0294 0.987 0.92
0207_0259 0.982 0.91
0032_0249 0.981 0.91
0165_0309 0.981 0.91
0067_0239 0.978 0.91
0183_0187 0.977 0.91
0122_0182 0.973 0.91
0266_0282 0.971 0.91
0100_0257 0.970 0.91
0034_0038 0.970 0.91
0038_0291 0.969 0.91
0158_0228 0.967 0.91
0156_0244 0.965 0.90
0089_0244 0.962 0.90
0151_0222 0.960 0.90
0135_0243 0.951 0.90
0151_0229 0.950 0.90
0195_0198 0.948 0.89
0226_0230 0.947 0.89
0189_0194 0.947 0.89
0278_0281 0.947 0.89
0193_0198 0.946 0.89
0326_0330 0.945 0.89
0239_0242 0.941 0.89
0036_0223 0.941 0.89
0033_0056 0.938 0.89
0139_0244 0.938 0.89
0079_0138 0.933 0.88
0267_0282 0.931 0.88
0095_0128 0.931 0.88
0224_0227 0.930 0.88
0118_0237 0.928 0.88
0213_0229 0.928 0.88
0207_0290 0.927 0.88
0033_0041 0.924 0.88
0148_0280 0.922 0.88
0066_0245 0.920 0.87
0158_0162 0.919 0.87
0165_0317 0.918 0.87
0041_0049 0.917 0.87
0061_0146 0.914 0.87
0118_0244 0.912 0.87
0015_0053 0.909 0.87
0040_0045 0.908 0.87
0035_0249 0.906 0.86
0160_0293 0.906 0.86
0050_0233 0.905 0.86
0169_0203 0.904 0.86
0117_0181 0.903 0.86
0039_0291 0.902 0.86
0314_0317 0.900 0.86
0155_0228 0.899 0.86
0158_0212 0.898 0.86
0276_0280 0.895 0.85
0015_0325 0.890 0.85
0138_0168 0.889 0.85
0212_0305 0.889 0.85
0171_0321 0.889 0.85
0196_0199 0.888 0.85
0033_0059 0.887 0.85
0082_0236 0.886 0.85
0156_0165 0.886 0.85
0141_0144 0.885 0.85
0084_0281 0.884 0.84
0016_0081 0.882 0.84
0166_0209 0.881 0.84
0045_0055 0.881 0.84
0122_0174 0.880 0.84
0027_0031 0.878 0.84
0063_0067 0.875 0.84
0226_0229 0.871 0.83
0099_0121 0.871 0.83
0173_0262 0.869 0.83
0125_0129 0.869 0.83
0099_0208 0.867 0.83
0229_0234 0.866 0.83
0036_0048 0.866 0.83
0026_0029 0.864 0.83
0204_0208 0.859 0.82
0199_0202 0.852 0.81
0033_0039 0.851 0.81
0093_0247 0.851 0.81
0199_0320 0.850 0.81
0193_0327 0.849 0.81
0165_0313 0.849 0.81
0220_0223 0.849 0.81
0045_0058 0.844 0.81
0202_0313 0.841 0.80
0025_0094 0.840 0.80
0143_0148 0.838 0.80
0128_0289 0.837 0.80
0125_0182 0.836 0.80
0214_0251 0.835 0.80
0052_0057 0.832 0.79
0034_0217 0.832 0.79
0100_0268 0.830 0.79
0173_0185 0.829 0.79
0206_0263 0.827 0.79
0221_0234 0.826 0.79
0029_0060 0.823 0.78
0074_0203 0.823 0.78
0216_0294 0.822 0.78
0036_0225 0.819 0.78
0139_0243 0.818 0.78
0168_0317 0.817 0.77
0158_0161 0.817 0.77
0208_0308 0.817 0.77
0312_0317 0.816 0.77
0070_0143 0.815 0.77
0294_0306 0.815 0.77
0062_0065 0.813 0.77
0030_0033 0.813 0.77
0223_0231 0.812 0.77
0214_0250 0.812 0.77
0054_0179 0.804 0.76
0063_0139 0.804 0.76
0036_0219 0.802 0.76
0179_0183 0.801 0.76
0054_0327 0.800 0.75
0249_0305 0.800 0.75
0206_0210 0.800 0.75
0137_0159 0.797 0.75
0152_0321 0.796 0.75
0183_0261 0.794 0.75
0035_0225 0.794 0.75
0214_0252 0.794 0.75
0033_0037 0.793 0.74
0032_0035 0.792 0.74
0237_0313 0.791 0.74
0081_0290 0.790 0.74
0300_0304 0.790 0.74
0095_0098 0.786 0.74
0291_0294 0.786 0.74
0316_0320 0.786 0.74
0215_0306 0.785 0.73
0220_0299 0.785 0.73
0269_0275 0.784 0.73
0141_0162 0.783 0.73
0224_0299 0.782 0.73
0126_0170 0.781 0.73
0169_0172 0.781 0.73
0200_0203 0.778 0.72
0085_0142 0.778 0.72
0027_0030 0.777 0.72
0053_0316 0.776 0.72
0041_0224 0.776 0.72
0121_0128 0.775 0.72
0216_0220 0.774 0.72
0277_0281 0.774 0.72
0260_0283 0.773 0.72
0129_0259 0.773 0.72
0216_0249 0.773 0.72
0221_0304 0.772 0.72
0017_0020 0.771 0.71
0019_0023 0.771 0.71
0287_0291 0.769 0.71
0037_0041 0.768 0.71
0170_0262 0.768 0.71
0102_0257 0.768 0.71
0300_0309 0.767 0.71
0024_0028 0.767 0.71
0303_0306 0.767 0.71
0114_0329 0.767 0.71
0114_0330 0.766 0.71
0073_0079 0.766 0.71
0183_0186 0.765 0.71
0092_0096 0.763 0.70
0092_0132 0.760 0.70
0062_0299 0.759 0.70
0285_0288 0.757 0.69
0216_0248 0.756 0.69
0211_0255 0.755 0.69
0149_0247 0.755 0.69
0250_0253 0.754 0.69
0145_0165 0.753 0.69
0225_0245 0.752 0.69
0063_0068 0.751 0.69
0259_0290 0.751 0.69
0051_0164 0.750 0.68
0015_0073 0.748 0.68
0068_0250 0.748 0.68
0035_0055 0.748 0.68
0207_0286 0.748 0.68
0281_0325 0.747 0.68
0122_0125 0.746 0.68
0136_0155 0.746 0.68
0225_0299 0.746 0.68
0307_0322 0.745 0.68
0165_0302 0.745 0.68
0048_0058 0.744 0.68
0189_0195 0.744 0.68
0045_0231 0.744 0.68
0117_0183 0.744 0.68
0141_0228 0.742 0.67
0086_0236 0.742 0.67
0090_0094 0.741 0.67
0075_0138 0.740 0.67
0014_0148 0.739 0.67
0215_0252 0.738 0.67
0123_0302 0.737 0.67
0032_0063 0.736 0.66
0121_0326 0.734 0.66
0104_0181 0.734 0.66
0029_0059 0.732 0.66
0013_0328 0.727 0.65
0299_0310 0.727 0.65
0045_0048 0.727 0.65
0172_0320 0.725 0.65
0026_0104 0.724 0.64
0029_0033 0.723 0.64
0016_0198 0.723 0.64
0018_0079 0.722 0.64
0124_0238 0.721 0.64
0091_0181 0.720 0.64
0229_0232 0.720 0.64
0238_0242 0.720 0.64
0037_0049 0.720 0.64
0172_0175 0.719 0.64
0167_0304 0.717 0.63
0286_0293 0.717 0.63
0179_0263 0.717 0.63
0231_0235 0.717 0.63
0035_0039 0.715 0.63
0085_0244 0.715 0.63
0221_0299 0.715 0.63
0032_0233 0.714 0.63
0292_0297 0.714 0.63
0092_0095 0.713 0.63
0142_0317 0.712 0.63
0086_0150 0.712 0.63
0255_0259 0.712 0.63
0049_0238 0.712 0.63
0030_0056 0.711 0.62
0048_0057 0.711 0.62
0099_0125 0.711 0.62
0256_0260 0.711 0.62
0258_0326 0.708 0.62
0157_0306 0.708 0.62
0134_0161 0.707 0.62
0090_0234 0.707 0.62
0205_0259 0.706 0.62
0122_0160 0.706 0.62
0017_0021 0.706 0.62
0173_0186 0.705 0.61
0223_0299 0.704 0.61
0084_0212 0.703 0.61
0164_0168 0.703 0.61
0308_0311 0.703 0.61
0057_0237 0.703 0.61
0089_0132 0.702 0.61
0090_0246 0.700 0.61
0076_0197 0.699 0.60
0030_0136 0.698 0.60
0029_0032 0.698 0.60
0027_0077 0.697 0.60
0155_0252 0.697 0.60
0186_0262 0.697 0.60
0026_0030 0.697 0.60
0139_0236 0.696 0.60
0090_0268 0.696 0.60
0096_0129 0.696 0.60
0228_0233 0.695 0.60
0148_0298 0.695 0.60
0187_0191 0.695 0.60
0055_0069 0.694 0.60
0103_0148 0.694 0.60
0187_0268 0.694 0.60
0303_0310 0.693 0.59
0032_0036 0.693 0.59
0155_0160 0.692 0.59
0186_0197 0.691 0.59
0299_0302 0.691 0.59
0136_0215 0.690 0.59
0085_0152 0.689 0.59
0040_0047 0.687 0.58
0237_0244 0.687 0.58
0213_0248 0.686 0.58
0145_0290 0.686 0.58
0135_0138 0.686 0.58
0059_0287 0.686 0.58
0175_0321 0.686 0.58
0059_0097 0.685 0.58
0135_0313 0.684 0.58
0122_0170 0.684 0.58
0105_0128 0.683 0.58
0074_0219 0.683 0.58
0258_0307 0.683 0.58
0052_0058 0.683 0.58
0197_0201 0.683 0.58
0072_0240 0.683 0.58
0228_0232 0.682 0.58
0031_0291 0.681 0.57
0144_0157 0.680 0.57
0271_0277 0.679 0.57
0272_0275 0.679 0.57
0194_0262 0.679 0.57
0050_0166 0.678 0.57
0139_0159 0.678 0.57
0187_0285 0.677 0.57
0211_0222 0.675 0.56
0162_0294 0.675 0.56
Local Interactions:
i_j Score Prob
0200_0201 3.268 1.00
0301_0303 2.536 1.00
0265_0266 2.077 1.00
0269_0270 1.759 1.00
0285_0286 1.734 1.00
0198_0200 1.597 1.00
0224_0226 1.505 1.00
0296_0297 1.490 1.00
0049_0050 1.483 1.00
0056_0057 1.479 1.00
0051_0052 1.434 1.00
0039_0040 1.343 0.99
0232_0233 1.259 0.99
0223_0225 1.245 0.98
0075_0076 1.230 0.98
0276_0277 1.226 0.98
0183_0184 1.202 0.98
0047_0048 1.197 0.98
0274_0275 1.183 0.98
0237_0238 1.174 0.98
0192_0193 1.171 0.98
0197_0198 1.168 0.97
0270_0271 1.139 0.97
0053_0054 1.138 0.97
0194_0195 1.125 0.97
0199_0201 1.105 0.96
0079_0080 1.063 0.95
0273_0274 1.060 0.95
0277_0278 1.053 0.95
0222_0224 1.034 0.94
0275_0277 1.033 0.94
0043_0045 1.025 0.93
0045_0047 1.023 0.93
0305_0306 1.014 0.93
0272_0273 0.993 0.92
0268_0270 0.986 0.92
0164_0165 0.985 0.92
0196_0197 0.976 0.91
0273_0275 0.971 0.91
0229_0230 0.966 0.91
0022_0023 0.965 0.90
0260_0261 0.941 0.89
0214_0215 0.930 0.88
0257_0258 0.928 0.88
0329_0330 0.924 0.88
0323_0324 0.918 0.87
0325_0326 0.903 0.86
0268_0269 0.901 0.86
0179_0180 0.884 0.84
0099_0100 0.873 0.83
0059_0060 0.872 0.83
0054_0056 0.868 0.83
0235_0236 0.867 0.83
0190_0191 0.866 0.83
0052_0053 0.864 0.83
0104_0105 0.858 0.82
0193_0194 0.857 0.82
0013_0014 0.852 0.81
0181_0183 0.851 0.81
0118_0120 0.839 0.80
0239_0240 0.834 0.79
0019_0020 0.828 0.79
0014_0015 0.821 0.78
0245_0247 0.820 0.78
0328_0329 0.817 0.77
0194_0196 0.804 0.76
0199_0200 0.790 0.74
0037_0038 0.787 0.74
0185_0186 0.785 0.73
0201_0202 0.783 0.73
0328_0330 0.777 0.72
0015_0016 0.776 0.72
0071_0073 0.773 0.72
0321_0322 0.773 0.72
0027_0028 0.768 0.71
0013_0015 0.768 0.71
0117_0118 0.763 0.70
0120_0122 0.762 0.70
0320_0321 0.760 0.70
0327_0328 0.760 0.70
0029_0030 0.752 0.69
0016_0017 0.742 0.67
0103_0105 0.741 0.67
0144_0145 0.738 0.67
0137_0138 0.735 0.66
0186_0187 0.734 0.66
0238_0240 0.733 0.66
0091_0092 0.722 0.64
0225_0226 0.709 0.62
0129_0130 0.709 0.62
0078_0080 0.704 0.61
0266_0267 0.699 0.60
0072_0073 0.698 0.60
0133_0134 0.698 0.60
0116_0118 0.692 0.59
0072_0074 0.690 0.59
0303_0304 0.689 0.59
0018_0019 0.688 0.59
0030_0032 0.683 0.58
0081_0082 0.680 0.57
0248_0249 0.680 0.57
0224_0225 0.680 0.57
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M T W S Y ...
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