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Instructions
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Coupling matrix for [S:0225] and [E:0232]
- A F I L V M W Y D E K R H N Q S T G P C
A 1.4 0.8 -0.5 0.6 -0.4 -0.7 0.4 0.3 -0.1 -0.5 -0.1 -0.1 0 -0.1 0.5 0.5 0.1 -0.4 -0.1 -0.1
F 0 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 0
I -0.1 -0.2 -0.1 0 0 -0.1 -0.1 0.8 0 -0.1 0 0 0 0 -0.1 -0.2 0.5 0 0 0
L -0.1 0.1 0 0 0 -0.1 -0.1 -0.3 0 -0.1 0 0 0 0 -0.1 -0.2 0 1 0 0
V -0.1 0.2 0 -0.1 0 -0.1 -0.1 0.8 0 -0.1 0 0 0 0 -0.1 -0.2 0 0 0 0
M 1.2 -0.4 -0.1 -0.1 -0.1 -0.1 0.1 0.9 0 -0.1 0 0 0 0 -0.1 -0.4 -0.1 -0.1 0 0
W 0 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 0
Y 0 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 0
D 0 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 0
E 0 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 0
K 0 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 0
R 0 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 0
H -0.1 -0.1 0 -0.1 0 0 -0.1 -0.2 0 0.8 0 0 0 0 0 -0.2 0 0 0 0
N -0.1 0.3 0 0 0 0 0 -0.2 0 0 0 0 0 0 0 -0.1 0 0 0 0
Q 0 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 0
S -0.4 -0.6 -0.2 -0.2 -0.2 -0.2 -0.3 1 0 0.7 0 0 0 0 0.1 1.7 -0.1 -0.1 0 0
T -0.1 -0.2 0 0 0 -0.1 -0.1 0.1 0 -0.1 0 0 0 0 0.8 -0.2 0 0 0 0
G -1 1 1.2 0.2 0.9 1.6 1 -0.6 -0.1 -0.8 -0.1 -0.1 -0.2 -0.1 -0.7 0.8 -0.4 -0.4 -0.1 -0.1
P -0.1 0.5 -0.1 -0.1 0 -0.1 -0.1 -0.3 0 0.7 0 0 0 0 -0.1 -0.2 0 0 0 0
C 0 -0.1 0 0 0 0 0 -0.1 0 0 0 0 0 0 0 -0.1 0 0 0 0
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0225 2.9 -0.8 0.2 -0.1 0 0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.8 -0.3 -0.5 -0.8 1.7 -0.1 3 0.2 -0.8
0232 0.7 1.5 0 0.2 -0.1 0.2 0.5 1.6 -0.7 0.5 -0.7 -0.7 -0.6 -0.7 0.2 0.2 -0.2 -0.2 -0.7 -0.7
Select residue pair below:
i_j Score Prob
0165_0168 2.157 0.99
0052_0080 2.070 0.99
0204_0273 1.973 0.98
0040_0044 1.952 0.98
0176_0201 1.683 0.94
0064_0069 1.660 0.93
0040_0128 1.645 0.93
0156_0178 1.617 0.92
0231_0250 1.574 0.90
0072_0218 1.564 0.90
0063_0068 1.533 0.89
0267_0318 1.529 0.89
0091_0094 1.514 0.88
0036_0039 1.507 0.88
0162_0168 1.500 0.87
0090_0094 1.484 0.87
0112_0115 1.474 0.86
0024_0027 1.449 0.85
0065_0112 1.438 0.84
0040_0071 1.435 0.84
0051_0210 1.428 0.84
0097_0130 1.411 0.83
0024_0029 1.404 0.82
0076_0219 1.402 0.82
0105_0243 1.397 0.82
0068_0084 1.388 0.81
0198_0266 1.383 0.81
0204_0274 1.376 0.80
0217_0223 1.361 0.79
0024_0028 1.342 0.78
0089_0100 1.333 0.77
0206_0271 1.318 0.76
0054_0088 1.316 0.76
0070_0236 1.306 0.75
0129_0134 1.305 0.75
0039_0042 1.298 0.75
0195_0314 1.289 0.74
0034_0038 1.284 0.74
0173_0274 1.282 0.73
0068_0098 1.281 0.73
0200_0266 1.272 0.73
0199_0203 1.259 0.71
0148_0223 1.255 0.71
0059_0090 1.255 0.71
0195_0231 1.249 0.71
0035_0039 1.246 0.70
0095_0163 1.244 0.70
0225_0232 1.241 0.70
0076_0105 1.236 0.69
0195_0251 1.232 0.69
0038_0042 1.228 0.69
0199_0205 1.223 0.68
0111_0115 1.223 0.68
0088_0122 1.217 0.68
0162_0165 1.214 0.67
0119_0322 1.214 0.67
0219_0223 1.209 0.67
0165_0302 1.208 0.67
0083_0148 1.205 0.67
0161_0210 1.190 0.65
0162_0251 1.190 0.65
0044_0278 1.182 0.64
0223_0232 1.179 0.64
0035_0038 1.178 0.64
0024_0030 1.177 0.64
0231_0251 1.176 0.64
0025_0028 1.166 0.63
0195_0280 1.160 0.62
0106_0137 1.156 0.62
0261_0301 1.154 0.62
0087_0099 1.153 0.62
0037_0041 1.152 0.61
0059_0147 1.149 0.61
0301_0323 1.147 0.61
0271_0323 1.145 0.61
0105_0109 1.141 0.60
0114_0117 1.140 0.60
0094_0215 1.137 0.60
0198_0263 1.129 0.59
0178_0239 1.128 0.59
0043_0078 1.123 0.59
0165_0316 1.123 0.59
0098_0175 1.120 0.58
0057_0184 1.115 0.58
0052_0245 1.113 0.58
0076_0083 1.111 0.57
0091_0120 1.110 0.57
0086_0100 1.109 0.57
0108_0236 1.109 0.57
0045_0151 1.108 0.57
0042_0249 1.105 0.57
0308_0321 1.103 0.56
0092_0262 1.101 0.56
0106_0151 1.100 0.56
0137_0151 1.099 0.56
0234_0263 1.098 0.56
0220_0301 1.097 0.56
0045_0098 1.096 0.56
0051_0216 1.092 0.55
0215_0288 1.091 0.55
0025_0029 1.088 0.55
0151_0175 1.085 0.55
0235_0238 1.084 0.55
0036_0042 1.083 0.54
0051_0255 1.081 0.54
0089_0101 1.080 0.54
0109_0236 1.080 0.54
0034_0039 1.075 0.54
0140_0238 1.075 0.54
0056_0060 1.074 0.53
0124_0300 1.067 0.53
0274_0297 1.067 0.53
0136_0246 1.066 0.53
0083_0219 1.062 0.52
0063_0098 1.061 0.52
0023_0028 1.060 0.52
0303_0322 1.058 0.52
0110_0241 1.057 0.52
0132_0173 1.053 0.51
0222_0235 1.049 0.51
0033_0037 1.047 0.51
0175_0205 1.047 0.51
0256_0277 1.045 0.50
0074_0318 1.045 0.50
0132_0144 1.040 0.50
0128_0169 1.039 0.50
0129_0278 1.036 0.49
0133_0176 1.036 0.49
0113_0255 1.032 0.49
0195_0248 1.032 0.49
0130_0143 1.030 0.49
0045_0175 1.028 0.49
0068_0175 1.026 0.48
0043_0095 1.026 0.48
0043_0283 1.025 0.48
0134_0175 1.025 0.48
0118_0323 1.024 0.48
0057_0060 1.024 0.48
0127_0250 1.020 0.48
0200_0263 1.019 0.48
0147_0285 1.018 0.48
0302_0319 1.012 0.47
0123_0216 1.011 0.47
0169_0172 1.010 0.47
0081_0084 1.010 0.47
0197_0201 1.009 0.47
0246_0300 1.009 0.47
0089_0099 1.009 0.47
0096_0259 1.008 0.47
0179_0274 1.008 0.47
0209_0234 1.005 0.46
0116_0278 1.002 0.46
0077_0211 1.002 0.46
0060_0083 1.001 0.46
0101_0235 1.000 0.46
0127_0297 1.000 0.46
0226_0264 0.998 0.45
0236_0280 0.997 0.45
0034_0082 0.995 0.45
0050_0286 0.994 0.45
0042_0094 0.993 0.45
0058_0149 0.992 0.45
0200_0312 0.991 0.45
0037_0071 0.991 0.45
0070_0084 0.989 0.45
0136_0309 0.988 0.44
0199_0318 0.988 0.44
0130_0171 0.985 0.44
0159_0168 0.983 0.44
0179_0313 0.980 0.44
0088_0242 0.979 0.44
0034_0235 0.979 0.44
0130_0151 0.976 0.43
0057_0157 0.976 0.43
0168_0174 0.974 0.43
0164_0168 0.973 0.43
0210_0221 0.969 0.42
0205_0239 0.967 0.42
0110_0321 0.966 0.42
0233_0237 0.966 0.42
0153_0157 0.964 0.42
0037_0174 0.964 0.42
0035_0140 0.964 0.42
0062_0161 0.963 0.42
0040_0201 0.963 0.42
0310_0318 0.963 0.42
0110_0219 0.962 0.42
0080_0084 0.962 0.42
0081_0218 0.962 0.42
0090_0100 0.960 0.42
0101_0140 0.960 0.42
0087_0233 0.960 0.42
0095_0198 0.959 0.41
0230_0253 0.959 0.41
0037_0136 0.959 0.41
0100_0235 0.956 0.41
0044_0128 0.956 0.41
0097_0167 0.955 0.41
0201_0280 0.955 0.41
0156_0282 0.953 0.41
0071_0083 0.953 0.41
0086_0089 0.953 0.41
0030_0216 0.952 0.41
0099_0235 0.952 0.41
0109_0113 0.951 0.41
0086_0099 0.951 0.41
0037_0231 0.951 0.41
0174_0201 0.951 0.41
0095_0181 0.951 0.41
0204_0271 0.950 0.41
0206_0236 0.949 0.40
0132_0280 0.949 0.40
0128_0308 0.948 0.40
0045_0068 0.948 0.40
0087_0100 0.947 0.40
0193_0294 0.945 0.40
0260_0297 0.945 0.40
0057_0194 0.944 0.40
0078_0277 0.944 0.40
0104_0314 0.942 0.40
0228_0276 0.941 0.40
0091_0136 0.941 0.40
0089_0105 0.940 0.40
0148_0308 0.939 0.39
0101_0224 0.938 0.39
0033_0176 0.937 0.39
0062_0116 0.937 0.39
0026_0029 0.937 0.39
0143_0309 0.937 0.39
0061_0115 0.936 0.39
0302_0322 0.934 0.39
0198_0270 0.933 0.39
0234_0319 0.933 0.39
0057_0287 0.932 0.39
0036_0045 0.932 0.39
0097_0172 0.932 0.39
0268_0274 0.930 0.39
0109_0149 0.929 0.38
0023_0030 0.928 0.38
0101_0238 0.928 0.38
0043_0253 0.928 0.38
0074_0267 0.927 0.38
0108_0273 0.927 0.38
0133_0251 0.926 0.38
0096_0117 0.926 0.38
0180_0246 0.925 0.38
0224_0238 0.925 0.38
0231_0280 0.925 0.38
0066_0205 0.925 0.38
0231_0253 0.924 0.38
0087_0235 0.923 0.38
0251_0314 0.922 0.38
0077_0208 0.921 0.38
0120_0125 0.921 0.38
0025_0030 0.921 0.38
0035_0101 0.920 0.38
0127_0275 0.920 0.38
0041_0137 0.919 0.37
0058_0116 0.919 0.37
0259_0317 0.918 0.37
0251_0319 0.918 0.37
0090_0244 0.917 0.37
0057_0226 0.916 0.37
0043_0113 0.915 0.37
0058_0187 0.913 0.37
0034_0052 0.913 0.37
0086_0237 0.913 0.37
0088_0283 0.913 0.37
0039_0045 0.911 0.37
0086_0101 0.911 0.37
0023_0029 0.910 0.37
0119_0271 0.910 0.37
0086_0224 0.908 0.36
0103_0234 0.908 0.36
0126_0282 0.907 0.36
0174_0308 0.907 0.36
0034_0080 0.907 0.36
0102_0106 0.904 0.36
0132_0201 0.904 0.36
0121_0210 0.903 0.36
0134_0246 0.902 0.36
0035_0238 0.901 0.36
0073_0177 0.900 0.36
0057_0212 0.898 0.35
0098_0106 0.898 0.35
0079_0094 0.897 0.35
0135_0139 0.897 0.35
0034_0145 0.896 0.35
0064_0250 0.895 0.35
0114_0159 0.894 0.35
0056_0122 0.893 0.35
0233_0238 0.892 0.35
0242_0265 0.891 0.35
0140_0145 0.891 0.35
0176_0250 0.889 0.35
0035_0224 0.889 0.35
0117_0273 0.888 0.34
0191_0285 0.887 0.34
0035_0235 0.886 0.34
0054_0116 0.884 0.34
0121_0180 0.883 0.34
0040_0177 0.883 0.34
0023_0027 0.882 0.34
0059_0315 0.881 0.34
0134_0317 0.881 0.34
0040_0054 0.880 0.34
0248_0314 0.879 0.34
0170_0176 0.878 0.34
0070_0223 0.878 0.34
0140_0235 0.878 0.34
0104_0195 0.878 0.34
0103_0175 0.877 0.33
0069_0076 0.877 0.33
0217_0243 0.877 0.33
0033_0109 0.875 0.33
0202_0237 0.875 0.33
0164_0245 0.874 0.33
0236_0246 0.873 0.33
0282_0320 0.872 0.33
0065_0113 0.872 0.33
0042_0045 0.871 0.33
0282_0306 0.871 0.33
0100_0140 0.870 0.33
0129_0245 0.870 0.33
0113_0204 0.870 0.33
0174_0251 0.869 0.33
0049_0123 0.868 0.33
0181_0251 0.868 0.33
0160_0178 0.866 0.32
0096_0208 0.866 0.32
0202_0238 0.865 0.32
0168_0300 0.865 0.32
0236_0279 0.864 0.32
0086_0238 0.864 0.32
0295_0301 0.864 0.32
0070_0296 0.863 0.32
0120_0158 0.863 0.32
0082_0299 0.863 0.32
0128_0177 0.863 0.32
0108_0144 0.862 0.32
0119_0193 0.862 0.32
0235_0244 0.862 0.32
0138_0321 0.862 0.32
0167_0306 0.861 0.32
0261_0264 0.861 0.32
0065_0162 0.861 0.32
0071_0219 0.861 0.32
0132_0176 0.859 0.32
0046_0132 0.858 0.32
0196_0236 0.857 0.32
0034_0090 0.857 0.32
0100_0238 0.857 0.32
0035_0100 0.857 0.32
0090_0233 0.856 0.31
0265_0268 0.856 0.31
0130_0231 0.856 0.31
0251_0254 0.854 0.31
0043_0158 0.854 0.31
0202_0233 0.854 0.31
0129_0175 0.853 0.31
0101_0222 0.853 0.31
0123_0256 0.852 0.31
0299_0317 0.852 0.31
0093_0195 0.850 0.31
0119_0154 0.850 0.31
0044_0126 0.849 0.31
0174_0231 0.849 0.31
0098_0278 0.848 0.31
0144_0276 0.848 0.31
0162_0231 0.847 0.31
0038_0045 0.847 0.31
0280_0314 0.847 0.31
0062_0088 0.847 0.31
0089_0235 0.846 0.31
0127_0209 0.846 0.31
0161_0213 0.845 0.30
0201_0218 0.845 0.30
0154_0220 0.845 0.30
0051_0213 0.844 0.30
0220_0226 0.844 0.30
0130_0175 0.843 0.30
0137_0175 0.843 0.30
0119_0261 0.843 0.30
0286_0299 0.842 0.30
0167_0308 0.841 0.30
0194_0262 0.841 0.30
0153_0268 0.841 0.30
0069_0097 0.841 0.30
0157_0271 0.841 0.30
0087_0140 0.840 0.30
0100_0239 0.839 0.30
0117_0172 0.837 0.30
0049_0268 0.836 0.30
0034_0222 0.836 0.30
0100_0224 0.835 0.30
0128_0251 0.834 0.30
0153_0190 0.833 0.29
0186_0189 0.833 0.29
0086_0235 0.833 0.29
0040_0203 0.831 0.29
0043_0110 0.831 0.29
0205_0244 0.830 0.29
0051_0121 0.830 0.29
0131_0145 0.830 0.29
0134_0151 0.829 0.29
0030_0050 0.829 0.29
0055_0059 0.827 0.29
0130_0165 0.826 0.29
0061_0077 0.826 0.29
0132_0218 0.826 0.29
0066_0128 0.826 0.29
0084_0101 0.826 0.29
0099_0222 0.825 0.29
0151_0155 0.824 0.29
0279_0320 0.823 0.29
0156_0171 0.823 0.29
0222_0238 0.823 0.29
0128_0201 0.822 0.28
0163_0171 0.821 0.28
0157_0324 0.820 0.28
0072_0294 0.820 0.28
0224_0235 0.820 0.28
0140_0224 0.819 0.28
0087_0202 0.819 0.28
0070_0211 0.819 0.28
0063_0205 0.819 0.28
0073_0226 0.818 0.28
0150_0200 0.818 0.28
0146_0269 0.818 0.28
0060_0262 0.817 0.28
0100_0222 0.817 0.28
0098_0130 0.817 0.28
0212_0289 0.816 0.28
0041_0063 0.816 0.28
0210_0219 0.815 0.28
0100_0244 0.814 0.28
0180_0280 0.814 0.28
0161_0212 0.814 0.28
0108_0146 0.814 0.28
0098_0199 0.813 0.28
0068_0203 0.813 0.28
0127_0176 0.813 0.28
0264_0277 0.813 0.28
0181_0263 0.812 0.28
0197_0316 0.812 0.28
0174_0306 0.812 0.28
0089_0237 0.812 0.28
Local Interactions:
i_j Score Prob
0242_0243 2.369 1.00
0024_0025 2.072 0.99
0038_0039 1.858 0.97
0222_0224 1.850 0.97
0080_0082 1.679 0.94
0027_0029 1.613 0.92
0035_0036 1.568 0.90
0034_0035 1.566 0.90
0028_0029 1.564 0.90
0028_0030 1.450 0.85
0036_0038 1.443 0.84
0081_0083 1.440 0.84
0025_0026 1.416 0.83
0197_0199 1.396 0.82
0297_0299 1.321 0.76
0029_0030 1.312 0.76
0034_0036 1.298 0.75
0024_0026 1.296 0.74
0082_0084 1.288 0.74
0100_0101 1.272 0.73
0111_0113 1.252 0.71
0144_0145 1.252 0.71
0186_0187 1.242 0.70
0292_0293 1.233 0.69
0023_0024 1.211 0.67
0213_0214 1.197 0.66
0023_0025 1.175 0.64
0143_0144 1.173 0.64
0026_0027 1.164 0.63
0049_0050 1.160 0.62
0205_0206 1.141 0.60
0027_0028 1.141 0.60
0285_0287 1.130 0.59
0276_0277 1.129 0.59
0049_0051 1.123 0.59
0099_0100 1.120 0.58
0292_0294 1.112 0.57
0293_0294 1.095 0.56
0252_0253 1.087 0.55
0212_0214 1.075 0.54
0102_0103 1.071 0.53
0233_0235 1.061 0.52
0025_0027 1.048 0.51
0237_0238 1.047 0.51
0321_0322 1.032 0.49
0215_0217 1.020 0.48
0171_0172 1.005 0.46
0218_0220 0.997 0.45
0302_0303 0.975 0.43
0199_0201 0.975 0.43
0031_0032 0.971 0.43
0121_0122 0.969 0.42
0256_0257 0.964 0.42
0098_0100 0.955 0.41
0230_0232 0.953 0.41
0187_0188 0.952 0.41
0257_0258 0.945 0.40
0188_0189 0.942 0.40
0218_0219 0.932 0.39
0284_0286 0.923 0.38
0174_0176 0.923 0.38
0248_0250 0.920 0.38
0296_0297 0.909 0.36
0180_0182 0.909 0.36
0099_0101 0.906 0.36
0290_0291 0.905 0.36
0050_0051 0.897 0.35
0026_0028 0.891 0.35
0288_0289 0.887 0.34
0093_0094 0.887 0.34
0319_0321 0.882 0.34
0322_0323 0.873 0.33
0087_0089 0.868 0.33
0210_0211 0.867 0.32
0188_0190 0.862 0.32
0304_0306 0.861 0.32
0284_0285 0.859 0.32
0299_0300 0.857 0.32
0306_0307 0.857 0.32
0173_0174 0.850 0.31
0301_0302 0.848 0.31
0212_0213 0.833 0.29
0184_0186 0.833 0.29
0291_0292 0.830 0.29
0288_0290 0.829 0.29
0039_0041 0.829 0.29
0185_0186 0.825 0.29
0235_0237 0.825 0.29
0241_0242 0.822 0.28
0294_0295 0.822 0.28
0281_0283 0.821 0.28
0186_0188 0.815 0.28
0030_0031 0.815 0.28
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M S V T R ...
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