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Instructions
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Coupling matrix for [V:0135] and [K:0144]
- A F I L V M W Y D E K R H N Q S T G P C
A -0.2 0.3 -0.2 0.1 0.1 0.8 -0.1 -0.1 -0.3 0.4 -0.2 -0.3 -0.1 0.7 0 -0.3 0 -0.3 0.3 0
F 0.6 -0.1 0.6 -0.2 -0.2 -0.1 -0.1 -0.1 -0.3 0 -0.4 0.4 -0.1 -0.3 0 -0.1 0.8 0 -0.3 0
I -0.3 -0.1 0.3 0.6 0.5 -0.2 -0.2 -0.1 -0.5 0.3 -0.1 -0.3 0.2 0.3 -0.4 -0.3 0.5 -0.2 0.4 0
L 1 -0.2 -0.1 0.6 0.3 -0.3 -0.2 -0.1 -0.3 -0.2 -0.2 0.4 -0.1 -0.6 0.6 -0.3 -0.4 0.3 0 -0.1
V 0.3 0.2 0.3 0.2 -0.3 -0.2 0.2 -0.1 -0.2 0.1 0.1 0.1 -0.1 0.3 -0.4 0 -0.4 0.3 0.2 0
M 0.1 -0.1 0.3 -0.1 0.3 0.3 0.5 0.2 0 -0.1 -0.2 -0.1 -0.1 -0.3 -0.4 0.2 -0.5 -0.1 0.2 0
W -0.2 0 -0.1 -0.1 -0.1 -0.1 0 0 0.5 -0.2 -0.3 -0.3 0.4 -0.2 0.1 -0.2 -0.4 -0.1 -0.1 0.4
Y -0.5 -0.2 0.1 -0.4 -0.1 -0.4 -0.4 -0.3 0.3 -0.3 1.4 0.4 0.2 -0.3 0.4 0.3 1.5 -0.2 -0.8 -0.2
D 0.1 -0.1 -0.1 -0.2 -0.2 -0.1 -0.1 -0.1 -0.1 -0.2 -0.1 0.3 -0.1 0 0.1 0.3 -0.1 -0.2 0.3 0
E 0 0.3 -0.1 -0.1 -0.2 -0.1 -0.1 -0.1 0.6 -0.3 0.2 -0.2 0.3 0.1 -0.1 -0.1 0.2 -0.2 0.1 0
K 0.2 -0.2 0.1 -0.4 -0.2 0 0.1 0.1 0.7 0 1.1 0.2 -0.4 0 -0.6 0.2 -0.3 0.2 -0.5 -0.1
R -0.1 0.2 -0.3 -0.2 -0.1 0.2 -0.2 0.3 0.1 0.1 -0.2 0.3 0.3 0 0.1 -0.4 -0.1 0.5 0.3 -0.1
H -0.2 -0.1 -0.1 -0.2 -0.2 0.3 -0.1 -0.1 0.2 0.4 0.6 -0.3 -0.1 -0.3 0.3 0.1 -0.4 0 0.3 0
N 0.4 0.3 -0.3 0.3 -0.3 -0.2 0.3 0.3 -0.3 0.5 0.1 -0.1 -0.3 -0.5 -0.3 0.4 -0.2 0.1 -0.3 -0.1
Q -0.4 -0.1 -0.1 0.1 -0.3 -0.1 -0.1 -0.1 0.6 -0.5 -0.1 0.3 -0.2 -0.1 0.3 0.6 0.2 -0.1 0.3 0
S 0.1 -0.2 -0.2 -0.3 0.3 0.4 -0.1 -0.1 -0.5 0.3 -0.3 -0.2 -0.3 1.1 0 0.5 -0.1 0 -0.2 -0.1
T -0.5 -0.1 -0.2 0.7 -0.2 0.1 -0.1 -0.1 0.3 0.4 -0.4 -0.1 0.2 0.6 -0.2 -0.2 -0.1 0.3 -0.4 0
G -0.5 -0.1 -0.2 0.2 0 -0.3 0.8 0.2 -0.1 -0.4 -0.3 -0.1 0.1 0.2 -0.5 0 0.8 -0.2 -0.2 -0.1
P -0.2 0 -0.1 -0.1 0 0.1 -0.1 0 0.1 0.2 -0.4 0 -0.1 -0.2 0.9 0 -0.2 -0.1 -0.2 0
C -0.1 0 0 -0.1 -0.1 0 0.4 0 -0.1 0.2 -0.1 -0.1 0 0.3 0.1 -0.2 0 -0.1 -0.1 0

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0135 0 0.3 0.3 0.6 0.2 -0.2 -0.8 1.3 -0.1 -0.2 0.7 0.6 -0.4 -0.3 -0.2 0.3 0.1 -0.3 -0.5 -0.5
0144 0.6 -1.3 -0.8 -0.2 -0.2 -0.7 -0.8 -1.2 0.4 0.5 0.5 0.7 -0.9 0.3 1 1.1 1.5 0.1 0.1 -1.7
Select residue pair below:
i_j Score Prob
0171_0174 4.578 1.00
0207_0211 3.912 1.00
0089_0093 3.090 1.00
0033_0037 2.897 1.00
0105_0216 2.790 1.00
0011_0086 2.724 1.00
0148_0151 2.702 1.00
0188_0193 2.684 1.00
0107_0111 2.597 1.00
0113_0206 2.341 1.00
0026_0030 2.333 1.00
0063_0067 2.293 1.00
0029_0033 2.168 1.00
0018_0094 2.080 1.00
0095_0220 2.041 1.00
0092_0096 2.023 1.00
0030_0034 1.982 1.00
0012_0015 1.981 1.00
0151_0158 1.900 1.00
0170_0174 1.877 1.00
0032_0069 1.848 1.00
0025_0069 1.825 1.00
0077_0081 1.824 1.00
0151_0165 1.798 1.00
0110_0114 1.763 1.00
0220_0224 1.723 1.00
0022_0076 1.708 1.00
0025_0072 1.670 1.00
0219_0226 1.637 1.00
0032_0062 1.620 1.00
0023_0027 1.593 1.00
0099_0220 1.585 1.00
0170_0173 1.578 1.00
0009_0013 1.563 1.00
0034_0063 1.546 1.00
0015_0018 1.522 1.00
0223_0226 1.468 1.00
0151_0173 1.459 1.00
0204_0208 1.446 1.00
0079_0082 1.444 1.00
0030_0033 1.439 1.00
0147_0159 1.437 1.00
0092_0227 1.436 1.00
0225_0229 1.427 1.00
0081_0090 1.408 1.00
0029_0070 1.402 0.99
0113_0210 1.402 0.99
0018_0021 1.372 0.99
0188_0196 1.361 0.99
0159_0191 1.357 0.99
0080_0086 1.355 0.99
0170_0176 1.353 0.99
0088_0092 1.342 0.99
0028_0065 1.335 0.99
0015_0019 1.317 0.99
0108_0112 1.313 0.99
0016_0020 1.296 0.99
0191_0195 1.295 0.99
0219_0223 1.284 0.99
0202_0205 1.278 0.99
0109_0213 1.272 0.99
0171_0176 1.270 0.99
0095_0099 1.262 0.99
0147_0151 1.259 0.99
0095_0224 1.247 0.99
0203_0207 1.246 0.98
0011_0015 1.239 0.98
0014_0018 1.235 0.98
0022_0073 1.233 0.98
0166_0169 1.229 0.98
0102_0220 1.225 0.98
0018_0022 1.222 0.98
0036_0066 1.222 0.98
0148_0171 1.199 0.98
0082_0090 1.174 0.98
0034_0038 1.174 0.98
0158_0164 1.165 0.97
0082_0091 1.162 0.97
0148_0189 1.159 0.97
0206_0210 1.150 0.97
0077_0080 1.147 0.97
0151_0156 1.137 0.97
0025_0029 1.136 0.97
0011_0014 1.129 0.97
0158_0161 1.129 0.97
0224_0227 1.128 0.97
0224_0228 1.113 0.96
0165_0173 1.111 0.96
0026_0073 1.095 0.96
0219_0222 1.092 0.96
0155_0186 1.088 0.96
0213_0219 1.079 0.95
0102_0217 1.078 0.95
0106_0110 1.076 0.95
0095_0227 1.071 0.95
0127_0130 1.059 0.95
0022_0077 1.057 0.95
0011_0018 1.053 0.95
0078_0093 1.047 0.94
0166_0170 1.029 0.94
0030_0037 1.015 0.93
0079_0094 1.014 0.93
0226_0230 1.007 0.93
0061_0094 1.006 0.93
0225_0228 1.003 0.93
0222_0230 0.995 0.92
0102_0106 0.993 0.92
0170_0175 0.992 0.92
0088_0091 0.989 0.92
0034_0076 0.987 0.92
0011_0022 0.986 0.92
0021_0072 0.983 0.91
0027_0030 0.981 0.91
0078_0090 0.979 0.91
0082_0087 0.979 0.91
0098_0105 0.977 0.91
0083_0091 0.975 0.91
0039_0062 0.971 0.91
0005_0010 0.969 0.91
0154_0158 0.968 0.91
0109_0206 0.967 0.91
0204_0207 0.967 0.91
0066_0070 0.965 0.90
0220_0223 0.965 0.90
0038_0063 0.963 0.90
0162_0189 0.961 0.90
0006_0009 0.960 0.90
0081_0087 0.952 0.90
0111_0115 0.946 0.89
0147_0165 0.940 0.89
0014_0022 0.936 0.89
0103_0107 0.934 0.88
0135_0138 0.928 0.88
0094_0223 0.926 0.88
0219_0224 0.924 0.88
0204_0214 0.922 0.88
0220_0226 0.919 0.87
0172_0177 0.918 0.87
0202_0206 0.910 0.87
0136_0144 0.909 0.87
0010_0017 0.906 0.86
0148_0173 0.905 0.86
0011_0020 0.903 0.86
0154_0197 0.891 0.85
0015_0080 0.889 0.85
0159_0189 0.888 0.85
0012_0084 0.887 0.85
0196_0200 0.884 0.84
0013_0018 0.881 0.84
0077_0089 0.877 0.84
0032_0065 0.877 0.84
0173_0176 0.876 0.84
0172_0176 0.876 0.84
0115_0118 0.869 0.83
0080_0083 0.868 0.83
0009_0016 0.868 0.83
0193_0196 0.860 0.82
0160_0164 0.858 0.82
0069_0098 0.856 0.82
0064_0108 0.854 0.82
0029_0066 0.854 0.82
0204_0211 0.853 0.81
0076_0092 0.851 0.81
0098_0219 0.850 0.81
0014_0017 0.847 0.81
0095_0228 0.846 0.81
0149_0153 0.843 0.80
0088_0227 0.841 0.80
0014_0098 0.839 0.80
0021_0219 0.837 0.80
0017_0021 0.833 0.79
0092_0224 0.832 0.79
0005_0009 0.830 0.79
0027_0070 0.829 0.79
0091_0227 0.825 0.78
0193_0197 0.824 0.78
0009_0017 0.823 0.78
0014_0094 0.823 0.78
0071_0221 0.822 0.78
0098_0101 0.821 0.78
0125_0130 0.821 0.78
0217_0220 0.820 0.78
0169_0172 0.815 0.77
0018_0076 0.814 0.77
0032_0206 0.810 0.77
0171_0175 0.809 0.77
0126_0131 0.800 0.75
0218_0222 0.800 0.75
0074_0184 0.794 0.75
0095_0223 0.791 0.74
0197_0201 0.791 0.74
0079_0083 0.787 0.74
0024_0027 0.786 0.74
0224_0229 0.784 0.73
0217_0231 0.777 0.72
0172_0178 0.776 0.72
0010_0022 0.774 0.72
0156_0164 0.770 0.71
0076_0079 0.768 0.71
0147_0174 0.767 0.71
0025_0076 0.766 0.71
0022_0080 0.766 0.71
0018_0079 0.765 0.71
0127_0131 0.763 0.70
0210_0214 0.758 0.70
0010_0013 0.756 0.69
0095_0102 0.755 0.69
0189_0193 0.754 0.69
0017_0025 0.754 0.69
0206_0222 0.754 0.69
0015_0084 0.750 0.68
0179_0184 0.750 0.68
0135_0144 0.749 0.68
0013_0016 0.746 0.68
0145_0149 0.744 0.68
0032_0066 0.740 0.67
0127_0159 0.739 0.67
0200_0204 0.738 0.67
0126_0148 0.738 0.67
0069_0075 0.737 0.67
0071_0096 0.736 0.66
0220_0227 0.735 0.66
0076_0082 0.734 0.66
0080_0226 0.733 0.66
0013_0094 0.731 0.66
0154_0157 0.730 0.65
0062_0075 0.728 0.65
0122_0125 0.728 0.65
0161_0164 0.726 0.65
0012_0082 0.721 0.64
0059_0094 0.720 0.64
0152_0172 0.720 0.64
0099_0224 0.719 0.64
0161_0189 0.718 0.64
0033_0160 0.717 0.63
0104_0211 0.716 0.63
0142_0145 0.715 0.63
0194_0209 0.714 0.63
0125_0145 0.713 0.63
0147_0185 0.712 0.63
0201_0204 0.709 0.62
0199_0207 0.709 0.62
0036_0040 0.709 0.62
0135_0151 0.706 0.62
0042_0046 0.705 0.61
0016_0019 0.704 0.61
0087_0092 0.702 0.61
0064_0104 0.700 0.61
0085_0098 0.699 0.60
0182_0185 0.699 0.60
0069_0082 0.698 0.60
0075_0083 0.697 0.60
0192_0196 0.696 0.60
0017_0219 0.696 0.60
0094_0098 0.695 0.60
0024_0215 0.695 0.60
0024_0105 0.691 0.59
0076_0105 0.688 0.59
0079_0096 0.688 0.59
0091_0229 0.688 0.59
0131_0142 0.684 0.58
0100_0120 0.684 0.58
0049_0052 0.682 0.58
0097_0104 0.682 0.58
0218_0231 0.681 0.57
0034_0039 0.679 0.57
0135_0148 0.679 0.57
0008_0016 0.678 0.57
0079_0086 0.677 0.57
0132_0136 0.673 0.56
0068_0101 0.672 0.56
0169_0174 0.672 0.56
0009_0021 0.671 0.56
0086_0099 0.671 0.56
0153_0193 0.670 0.56
0209_0213 0.670 0.56
0103_0111 0.669 0.55
0072_0079 0.668 0.55
0127_0135 0.667 0.55
0165_0185 0.667 0.55
0036_0063 0.666 0.55
0041_0149 0.666 0.55
0071_0085 0.666 0.55
0190_0194 0.665 0.55
0070_0074 0.665 0.55
0074_0179 0.662 0.54
0034_0037 0.662 0.54
0099_0102 0.662 0.54
0029_0062 0.662 0.54
0077_0212 0.661 0.54
0127_0178 0.660 0.54
0106_0213 0.659 0.54
0162_0165 0.658 0.54
0083_0086 0.658 0.54
0163_0184 0.656 0.53
0055_0068 0.656 0.53
0094_0209 0.653 0.53
0151_0157 0.653 0.53
0028_0068 0.651 0.52
0026_0033 0.650 0.52
0134_0137 0.649 0.52
0222_0227 0.647 0.52
0102_0216 0.646 0.52
0146_0184 0.645 0.51
0165_0175 0.645 0.51
0202_0220 0.645 0.51
0039_0042 0.641 0.51
0072_0075 0.641 0.51
0124_0130 0.641 0.51
0127_0144 0.641 0.51
0165_0174 0.639 0.50
0024_0038 0.639 0.50
0109_0211 0.637 0.50
0215_0221 0.637 0.50
0024_0102 0.635 0.50
0111_0214 0.635 0.50
0113_0145 0.634 0.49
0206_0215 0.634 0.49
0142_0149 0.633 0.49
0129_0143 0.632 0.49
0023_0074 0.628 0.48
0029_0073 0.627 0.48
0101_0105 0.626 0.48
0100_0110 0.626 0.48
0217_0223 0.626 0.48
0010_0014 0.624 0.48
0176_0180 0.624 0.48
0221_0225 0.623 0.48
0164_0171 0.623 0.48
0088_0228 0.623 0.48
0146_0192 0.623 0.48
0131_0147 0.622 0.47
0071_0089 0.622 0.47
0126_0134 0.622 0.47
0031_0081 0.621 0.47
0097_0219 0.620 0.47
0011_0021 0.620 0.47
0030_0044 0.619 0.47
0033_0152 0.619 0.47
0170_0185 0.617 0.47
0164_0189 0.616 0.46
0104_0204 0.616 0.46
0223_0230 0.615 0.46
Local Interactions:
i_j Score Prob
0161_0163 4.074 1.00
0173_0174 3.748 1.00
0171_0173 3.064 1.00
0161_0162 2.725 1.00
0162_0163 2.680 1.00
0134_0135 2.568 1.00
0156_0158 2.415 1.00
0164_0165 2.285 1.00
0170_0171 2.195 1.00
0157_0158 2.017 1.00
0087_0089 1.724 1.00
0021_0022 1.702 1.00
0005_0006 1.627 1.00
0172_0174 1.599 1.00
0082_0083 1.488 1.00
0126_0127 1.452 1.00
0156_0157 1.437 1.00
0017_0018 1.418 1.00
0018_0020 1.416 1.00
0207_0208 1.410 1.00
0084_0085 1.372 0.99
0185_0186 1.321 0.99
0183_0185 1.319 0.99
0061_0062 1.307 0.99
0223_0224 1.306 0.99
0004_0005 1.305 0.99
0011_0012 1.251 0.99
0174_0176 1.247 0.99
0224_0225 1.228 0.98
0189_0190 1.227 0.98
0136_0137 1.220 0.98
0041_0042 1.206 0.98
0175_0176 1.203 0.98
0116_0117 1.194 0.98
0176_0177 1.183 0.98
0101_0102 1.177 0.98
0177_0179 1.167 0.97
0171_0172 1.165 0.97
0183_0184 1.144 0.97
0135_0136 1.131 0.97
0186_0187 1.113 0.96
0228_0229 1.112 0.96
0028_0029 1.106 0.96
0169_0170 1.098 0.96
0051_0052 1.078 0.95
0127_0128 1.076 0.95
0128_0130 1.072 0.95
0219_0220 1.066 0.95
0184_0185 1.064 0.95
0170_0172 1.061 0.95
0222_0223 1.055 0.95
0033_0034 1.015 0.93
0227_0229 1.008 0.93
0147_0148 0.996 0.92
0177_0178 0.977 0.91
0220_0222 0.974 0.91
0010_0011 0.973 0.91
0056_0058 0.959 0.90
0053_0054 0.957 0.90
0043_0044 0.952 0.90
0135_0137 0.949 0.89
0040_0041 0.944 0.89
0141_0142 0.933 0.88
0180_0181 0.927 0.88
0201_0202 0.925 0.88
0042_0044 0.921 0.88
0052_0053 0.915 0.87
0085_0087 0.912 0.87
0040_0042 0.911 0.87
0009_0010 0.911 0.87
0009_0011 0.910 0.87
0081_0082 0.905 0.86
0055_0056 0.904 0.86
0182_0184 0.904 0.86
0136_0138 0.901 0.86
0006_0008 0.877 0.84
0187_0188 0.876 0.84
0124_0125 0.875 0.84
0205_0206 0.871 0.83
0227_0228 0.870 0.83
0046_0047 0.869 0.83
0049_0050 0.867 0.83
0049_0051 0.866 0.83
0015_0017 0.861 0.82
0223_0225 0.857 0.82
0176_0178 0.850 0.81
0130_0131 0.849 0.81
0050_0051 0.845 0.81
0186_0188 0.840 0.80
0065_0067 0.830 0.79
0231_0232 0.819 0.78
0166_0167 0.817 0.77
0060_0061 0.815 0.77
0140_0141 0.812 0.77
0038_0039 0.809 0.77
0012_0014 0.808 0.76
0108_0109 0.796 0.75
0008_0009 0.793 0.74
0160_0161 0.793 0.74
0061_0063 0.790 0.74
0137_0138 0.789 0.74
0110_0111 0.785 0.73
0089_0090 0.783 0.73
0153_0154 0.775 0.72
0164_0166 0.768 0.71
0195_0196 0.757 0.69
0139_0141 0.757 0.69
0070_0071 0.753 0.69
0200_0201 0.749 0.68
0004_0006 0.740 0.67
0168_0170 0.735 0.66
0034_0035 0.734 0.66
0084_0086 0.731 0.66
0128_0129 0.729 0.65
0036_0038 0.720 0.64
0020_0022 0.714 0.63
0016_0018 0.708 0.62
0010_0012 0.694 0.60
0182_0183 0.688 0.59
0051_0053 0.687 0.58
0076_0077 0.684 0.58
0054_0056 0.679 0.57
0160_0162 0.678 0.57
0145_0146 0.677 0.57
0122_0123 0.677 0.57
0087_0088 0.670 0.56
0075_0076 0.657 0.53
0045_0046 0.657 0.53
0173_0175 0.656 0.53
0152_0153 0.656 0.53
0219_0221 0.656 0.53
0074_0075 0.654 0.53
0020_0021 0.654 0.53
0138_0139 0.654 0.53
0221_0223 0.649 0.52
0221_0222 0.647 0.52
0206_0207 0.645 0.51
0018_0019 0.645 0.51
0007_0008 0.645 0.51
0165_0166 0.643 0.51
0080_0082 0.641 0.51
0100_0101 0.638 0.50
0132_0133 0.636 0.50
0140_0142 0.634 0.49
0056_0057 0.634 0.49
0012_0013 0.629 0.49
0044_0045 0.625 0.48
0050_0052 0.624 0.48
0167_0168 0.622 0.47
0134_0136 0.622 0.47
0150_0151 0.622 0.47
0218_0219 0.620 0.47
0125_0127 0.618 0.47
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: M G V E G ...

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