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Instructions
  • Use the menu to the right to browse the coupling matrix.
Coupling matrix for [F:0035] and [L:0041]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.3 -0.5 0 -0.2 -0.1 0.1 -0.2 -0.5 0.8 0.3 0.3 -0.2 -0.1 -0.1 -0.1 0.2 0.3 -0.1 -0.2 0.3
F -0.6 0.5 -0.3 0.3 0.1 0.6 -0.1 -0.1 0.7 0.3 0 -0.9 0.2 -0.2 0.3 -0.6 -0.1 0.2 -0.1 -0.2
I 0 0.3 0 -0.5 0.3 0.3 0.7 -0.1 0.3 0.1 -0.3 0 0.2 0.1 -0.3 0 0.1 0.3 -0.4 -0.3
L -0.3 0.2 0.3 0.9 0.6 0.9 -0.6 0.4 -0.7 0.4 -0.2 -0.3 0.6 0.6 0 0.1 -0.1 -0.3 -0.4 -0.4
V 0.4 0 -0.1 0.8 0.1 0.2 -0.3 0 -0.4 -0.3 -0.5 -0.6 0.5 0.6 0 0.1 0.6 -0.1 0.2 0.3
M -0.1 -0.5 -0.3 0.6 0.8 1.3 -0.1 0.1 -0.3 -0.6 0.2 0.2 0 0 -0.3 -0.4 0.2 -0.2 -0.1 -0.2
W 0 -0.1 -0.2 0.7 0.2 -0.2 0 -0.1 -0.1 -0.3 -0.2 0.3 -0.2 -0.2 -0.2 -0.2 -0.1 0 0 -0.1
Y -0.1 -0.3 0.4 0.9 0.1 -0.4 -0.1 -0.4 -0.1 1 -1 -0.3 1.1 -0.5 1 -0.5 0 -0.2 -0.1 0.1
D -0.2 -0.2 0.2 0.2 -0.3 0.1 0 -0.1 -0.2 0.3 -0.5 -0.2 -0.2 -0.1 0.5 0.6 -0.3 -0.1 0 -0.1
E 0.2 0.2 -0.1 0.6 -0.2 0.2 -0.1 -0.5 0.5 -0.2 -0.2 0.2 -0.5 0 -0.1 -0.2 0.1 -0.3 0.2 0.6
K -0.2 0.3 0.2 0 -0.5 -0.5 0.6 -0.2 -0.5 0.5 1.2 1.6 -0.5 -0.1 -0.1 -0.2 -0.6 0.1 -0.2 -0.4
R 0.6 -0.5 -0.2 0 -0.6 -0.5 -0.1 0 -0.4 0.1 0.5 1 -0.7 0.4 0.2 0.4 0.2 -0.2 -0.1 -0.3
H -0.3 0.1 -0.5 -0.5 0.5 -0.1 -0.1 -0.2 0.2 0.4 -0.4 -0.4 -0.2 -0.3 0 0.7 0.3 0.3 -0.1 0.2
N -0.3 -0.2 1.3 -0.7 0.4 -0.3 0 0.2 -0.2 -0.5 0.6 0.6 -0.4 -0.3 -0.1 -0.3 -0.3 -0.1 -0.1 0.3
Q 0.7 0 0.1 0.2 0.3 0 -0.1 -0.4 0.1 -0.6 0.3 -0.2 -0.1 0.7 -0.3 0.2 0.1 -0.2 -0.2 -0.2
S 0.5 -0.6 0.1 0 -0.5 0.3 -0.1 -0.5 -0.2 -0.1 0.9 -0.3 -0.1 -0.7 0.8 -0.2 0 0.8 -0.2 -0.1
T -0.1 -0.2 -0.1 -0.6 -0.5 -0.8 0.2 1 -0.3 0.1 -0.1 0 0.2 0 0.1 0 -0.2 0.5 0.9 0.5
G 0.4 0.2 0.2 -0.3 0.3 -0.4 -0.1 -0.2 0.2 -0.6 0.1 -0.1 0.6 -0.1 -0.8 -0.1 0.5 -0.1 -0.1 -0.2
P 0.2 0.4 -0.5 -0.6 -0.3 0 -0.3 0.1 0.1 0.3 0.7 0 0.3 -0.5 0.9 0.8 0.2 -0.6 -0.1 -0.3
C -0.5 0.7 -0.3 -1 -0.3 -0.4 0.4 0.5 0.2 -0.5 -0.5 0.8 0 0.2 -0.4 -0.2 -0.3 -0.1 -0.1 0.7
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0035 0.8 -0.4 1.3 2.1 1.4 -0.3 -1.9 0.1 -1.6 0.2 0.1 -0.1 -1 -1.2 0 0.1 0.4 -1 1.4 -1
0041 0.6 -0.1 0.3 1.2 -0.3 0.1 -1.2 -1 -0.8 -0.3 1.4 1.4 0.2 -0.2 1.5 -0.1 0.2 -0.6 -1.3 -0.5
Select residue pair below:
i_j Score Prob
0064_0091 4.173 1.00
0024_0093 3.596 1.00
0177_0202 3.502 1.00
0149_0152 3.055 1.00
0019_0056 2.553 1.00
0133_0204 2.305 1.00
0057_0061 2.259 1.00
0034_0037 2.226 1.00
0056_0059 2.186 1.00
0105_0109 2.041 1.00
0148_0151 2.032 1.00
0170_0174 2.015 1.00
0045_0101 1.987 1.00
0169_0172 1.985 1.00
0180_0194 1.977 1.00
0128_0135 1.940 1.00
0128_0132 1.900 1.00
0180_0198 1.826 1.00
0128_0169 1.790 1.00
0067_0071 1.750 1.00
0016_0060 1.715 1.00
0053_0101 1.693 1.00
0157_0160 1.675 1.00
0049_0105 1.663 1.00
0052_0056 1.579 1.00
0170_0209 1.478 1.00
0049_0101 1.465 1.00
0199_0203 1.464 1.00
0147_0152 1.463 1.00
0165_0169 1.457 1.00
0135_0139 1.455 1.00
0125_0129 1.447 1.00
0023_0048 1.420 1.00
0043_0046 1.414 1.00
0024_0096 1.405 0.99
0016_0056 1.398 0.99
0021_0093 1.382 0.99
0166_0212 1.361 0.99
0095_0099 1.356 0.99
0089_0093 1.352 0.99
0057_0098 1.352 0.99
0206_0209 1.341 0.99
0017_0093 1.336 0.99
0023_0026 1.322 0.99
0091_0095 1.303 0.99
0190_0193 1.298 0.99
0210_0214 1.296 0.99
0011_0015 1.261 0.99
0202_0206 1.260 0.99
0099_0103 1.252 0.99
0178_0182 1.244 0.98
0195_0199 1.243 0.98
0159_0212 1.233 0.98
0092_0096 1.213 0.98
0171_0174 1.210 0.98
0155_0159 1.209 0.98
0096_0100 1.184 0.98
0041_0104 1.182 0.98
0203_0207 1.182 0.98
0005_0069 1.182 0.98
0094_0101 1.181 0.98
0156_0159 1.179 0.98
0032_0041 1.176 0.98
0155_0158 1.173 0.98
0159_0163 1.161 0.97
0196_0200 1.159 0.97
0064_0067 1.157 0.97
0042_0112 1.149 0.97
0094_0098 1.145 0.97
0207_0211 1.145 0.97
0032_0037 1.144 0.97
0038_0108 1.120 0.96
0147_0151 1.114 0.96
0042_0109 1.111 0.96
0026_0044 1.111 0.96
0063_0067 1.104 0.96
0109_0113 1.103 0.96
0054_0057 1.102 0.96
0064_0068 1.098 0.96
0060_0094 1.095 0.96
0038_0112 1.095 0.96
0026_0052 1.085 0.96
0065_0069 1.084 0.96
0206_0210 1.083 0.96
0048_0101 1.081 0.95
0039_0043 1.079 0.95
0017_0021 1.071 0.95
0101_0105 1.069 0.95
0067_0085 1.068 0.95
0198_0202 1.066 0.95
0177_0181 1.065 0.95
0019_0023 1.065 0.95
0139_0142 1.064 0.95
0040_0043 1.062 0.95
0049_0102 1.061 0.95
0009_0013 1.059 0.95
0196_0199 1.050 0.94
0018_0022 1.046 0.94
0133_0137 1.046 0.94
0192_0195 1.044 0.94
0174_0178 1.036 0.94
0068_0071 1.034 0.94
0129_0133 1.030 0.94
0023_0052 1.029 0.94
0061_0065 1.028 0.94
0022_0026 1.017 0.93
0009_0067 1.015 0.93
0045_0048 1.015 0.93
0062_0066 1.014 0.93
0126_0130 1.014 0.93
0148_0152 1.011 0.93
0039_0116 1.008 0.93
0049_0054 0.999 0.92
0046_0105 0.998 0.92
0058_0061 0.997 0.92
0116_0120 0.990 0.92
0044_0047 0.988 0.92
0063_0066 0.984 0.92
0103_0106 0.983 0.91
0163_0167 0.979 0.91
0082_0086 0.977 0.91
0017_0089 0.974 0.91
0175_0178 0.969 0.91
0132_0135 0.966 0.91
0032_0038 0.963 0.90
0193_0197 0.962 0.90
0024_0100 0.961 0.90
0077_0080 0.960 0.90
0125_0128 0.958 0.90
0172_0175 0.954 0.90
0153_0157 0.951 0.90
0176_0180 0.947 0.89
0127_0130 0.939 0.89
0139_0165 0.931 0.88
0122_0126 0.929 0.88
0163_0212 0.928 0.88
0184_0191 0.922 0.88
0103_0107 0.921 0.88
0131_0135 0.920 0.87
0052_0055 0.918 0.87
0187_0190 0.917 0.87
0042_0105 0.914 0.87
0178_0181 0.908 0.87
0117_0120 0.907 0.86
0179_0182 0.906 0.86
0008_0012 0.906 0.86
0123_0127 0.901 0.86
0038_0041 0.901 0.86
0013_0063 0.897 0.86
0028_0100 0.887 0.85
0005_0008 0.882 0.84
0120_0124 0.881 0.84
0199_0202 0.880 0.84
0038_0042 0.879 0.84
0135_0169 0.878 0.84
0197_0200 0.877 0.84
0067_0070 0.871 0.83
0115_0118 0.869 0.83
0068_0072 0.869 0.83
0188_0191 0.862 0.82
0124_0128 0.860 0.82
0068_0091 0.858 0.82
0183_0205 0.857 0.82
0200_0203 0.855 0.82
0180_0184 0.843 0.80
0040_0044 0.842 0.80
0127_0131 0.841 0.80
0133_0197 0.839 0.80
0118_0135 0.836 0.80
0007_0011 0.836 0.80
0160_0163 0.831 0.79
0066_0069 0.831 0.79
0123_0126 0.830 0.79
0117_0121 0.828 0.79
0082_0085 0.827 0.79
0111_0115 0.825 0.78
0106_0110 0.820 0.78
0012_0066 0.820 0.78
0059_0062 0.816 0.77
0191_0195 0.815 0.77
0181_0185 0.814 0.77
0167_0170 0.814 0.77
0188_0194 0.811 0.77
0033_0037 0.811 0.77
0132_0173 0.809 0.77
0162_0166 0.806 0.76
0060_0064 0.805 0.76
0079_0083 0.802 0.76
0080_0083 0.801 0.76
0092_0095 0.797 0.75
0192_0196 0.796 0.75
0075_0078 0.796 0.75
0203_0206 0.795 0.75
0156_0160 0.791 0.74
0014_0018 0.791 0.74
0205_0209 0.788 0.74
0078_0082 0.787 0.74
0159_0162 0.785 0.73
0031_0041 0.785 0.73
0168_0172 0.784 0.73
0132_0162 0.782 0.73
0024_0028 0.781 0.73
0042_0108 0.779 0.73
0030_0104 0.778 0.72
0053_0056 0.778 0.72
0071_0075 0.776 0.72
0013_0090 0.775 0.72
0067_0081 0.774 0.72
0010_0014 0.773 0.72
0071_0082 0.771 0.71
0095_0098 0.770 0.71
0193_0196 0.762 0.70
0125_0135 0.762 0.70
0119_0122 0.760 0.70
0097_0101 0.760 0.70
0140_0143 0.760 0.70
0184_0188 0.758 0.70
0165_0168 0.757 0.69
0081_0087 0.757 0.69
0140_0204 0.755 0.69
0180_0195 0.755 0.69
0102_0106 0.753 0.69
0020_0094 0.748 0.68
0181_0184 0.747 0.68
0102_0105 0.746 0.68
0037_0041 0.744 0.68
0025_0029 0.743 0.67
0062_0065 0.739 0.67
0020_0023 0.738 0.67
0155_0215 0.737 0.67
0184_0195 0.735 0.66
0147_0150 0.734 0.66
0185_0188 0.734 0.66
0210_0213 0.732 0.66
0125_0180 0.730 0.65
0135_0165 0.728 0.65
0174_0177 0.726 0.65
0132_0139 0.725 0.65
0053_0057 0.725 0.65
0131_0138 0.723 0.64
0136_0208 0.719 0.64
0173_0205 0.717 0.63
0160_0164 0.716 0.63
0046_0109 0.714 0.63
0118_0180 0.713 0.63
0161_0165 0.711 0.62
0041_0044 0.711 0.62
0013_0017 0.710 0.62
0017_0084 0.709 0.62
0016_0090 0.708 0.62
0067_0087 0.708 0.62
0014_0021 0.706 0.62
0027_0048 0.705 0.61
0118_0122 0.705 0.61
0202_0205 0.705 0.61
0200_0207 0.702 0.61
0166_0169 0.698 0.60
0161_0164 0.696 0.60
0083_0089 0.695 0.60
0102_0109 0.694 0.60
0180_0183 0.694 0.60
0035_0041 0.692 0.59
0004_0007 0.692 0.59
0049_0098 0.692 0.59
0177_0198 0.691 0.59
0018_0021 0.690 0.59
0140_0211 0.690 0.59
0135_0158 0.690 0.59
0196_0207 0.689 0.59
0066_0070 0.688 0.59
0047_0062 0.688 0.59
0053_0094 0.687 0.58
0075_0081 0.686 0.58
0182_0186 0.686 0.58
0200_0204 0.684 0.58
0058_0062 0.684 0.58
0065_0068 0.681 0.57
0056_0060 0.681 0.57
0114_0117 0.681 0.57
0029_0041 0.681 0.57
0005_0073 0.681 0.57
0017_0060 0.680 0.57
0142_0145 0.680 0.57
0083_0086 0.679 0.57
0083_0087 0.679 0.57
0006_0074 0.677 0.57
0060_0063 0.674 0.56
0023_0094 0.674 0.56
0069_0072 0.673 0.56
0208_0211 0.673 0.56
0008_0066 0.668 0.55
0039_0112 0.667 0.55
0110_0114 0.667 0.55
0166_0208 0.665 0.55
0120_0123 0.664 0.55
0045_0104 0.660 0.54
0012_0062 0.658 0.54
0115_0122 0.657 0.53
0089_0092 0.653 0.53
0154_0158 0.652 0.53
0125_0169 0.651 0.52
0162_0212 0.651 0.52
0113_0116 0.646 0.52
0048_0053 0.645 0.51
0201_0207 0.644 0.51
0030_0044 0.643 0.51
0198_0205 0.643 0.51
0015_0059 0.641 0.51
0020_0093 0.641 0.51
0139_0143 0.636 0.50
0204_0207 0.636 0.50
0134_0138 0.635 0.50
0126_0197 0.635 0.50
0175_0179 0.633 0.49
0023_0097 0.632 0.49
0203_0210 0.630 0.49
0187_0191 0.628 0.48
0123_0131 0.626 0.48
0084_0089 0.625 0.48
Local Interactions:
i_j Score Prob
0050_0052 3.407 1.00
0149_0150 3.125 1.00
0150_0152 2.970 1.00
0051_0052 2.608 1.00
0148_0149 2.369 1.00
0075_0076 2.006 1.00
0188_0189 2.002 1.00
0187_0188 1.819 1.00
0147_0148 1.789 1.00
0085_0087 1.745 1.00
0031_0032 1.720 1.00
0074_0075 1.703 1.00
0147_0149 1.525 1.00
0142_0143 1.470 1.00
0078_0079 1.459 1.00
0076_0077 1.408 1.00
0033_0034 1.394 0.99
0081_0083 1.347 0.99
0079_0080 1.301 0.99
0138_0139 1.283 0.99
0151_0152 1.224 0.98
0022_0023 1.219 0.98
0150_0151 1.093 0.96
0083_0084 1.075 0.95
0141_0142 1.058 0.95
0075_0077 1.056 0.95
0143_0144 1.052 0.95
0118_0119 1.051 0.94
0011_0012 1.045 0.94
0077_0078 1.039 0.94
0077_0079 1.016 0.93
0144_0146 1.015 0.93
0184_0186 1.008 0.93
0073_0074 1.004 0.93
0127_0128 0.996 0.92
0085_0086 0.986 0.92
0188_0190 0.980 0.91
0148_0150 0.972 0.91
0063_0064 0.951 0.90
0079_0081 0.948 0.89
0145_0146 0.907 0.86
0050_0051 0.905 0.86
0170_0171 0.895 0.85
0003_0004 0.888 0.85
0167_0168 0.878 0.84
0214_0215 0.870 0.83
0206_0207 0.864 0.83
0055_0056 0.861 0.82
0198_0199 0.856 0.82
0115_0116 0.856 0.82
0026_0027 0.853 0.81
0180_0181 0.847 0.81
0171_0172 0.817 0.77
0141_0143 0.810 0.77
0201_0202 0.799 0.75
0004_0005 0.798 0.75
0189_0190 0.795 0.75
0005_0006 0.783 0.73
0211_0212 0.774 0.72
0162_0163 0.773 0.72
0129_0130 0.772 0.72
0082_0083 0.770 0.71
0095_0096 0.761 0.70
0041_0042 0.758 0.70
0149_0151 0.738 0.67
0083_0085 0.735 0.66
0089_0090 0.734 0.66
0087_0088 0.731 0.66
0097_0098 0.731 0.66
0032_0034 0.730 0.65
0176_0177 0.730 0.65
0187_0189 0.729 0.65
0192_0193 0.726 0.65
0009_0010 0.722 0.64
0084_0085 0.722 0.64
0191_0193 0.722 0.64
0078_0080 0.722 0.64
0114_0115 0.710 0.62
0202_0204 0.705 0.61
0073_0075 0.703 0.61
0003_0005 0.699 0.60
0139_0140 0.699 0.60
0029_0031 0.695 0.60
0213_0215 0.688 0.59
0191_0192 0.683 0.58
0032_0033 0.676 0.57
0143_0145 0.676 0.57
0122_0123 0.673 0.56
0059_0060 0.667 0.55
0012_0013 0.665 0.55
0202_0203 0.660 0.54
0122_0124 0.654 0.53
0146_0147 0.652 0.53
0068_0069 0.652 0.53
0196_0197 0.647 0.52
0185_0186 0.645 0.51
0116_0117 0.643 0.51
0031_0033 0.643 0.51
0006_0007 0.638 0.50
0205_0207 0.631 0.49
0105_0106 0.630 0.49
0119_0120 0.629 0.49
0013_0014 0.627 0.48
0179_0180 0.625 0.48
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: E L Q L R ...
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