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1BE9_A PDZ Return to Main Page

Instructions
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Coupling matrix for [Y:0101] and [F:0104]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.1 -0.2 0.5 0 -0.2 -0.5 -0.1 -0.1 0.3 0.2 -0.4 0.7 0.3 -0.4 0 0.2 0 0.1 0.3 -0.2
F -0.2 0.2 0.8 -0.1 -0.1 0.5 0.6 -0.3 -0.1 -0.5 -0.2 0.2 -0.2 -0.5 -0.2 -0.5 -0.2 -0.2 0.4 -0.1
I -0.2 -0.2 -0.3 -0.3 -0.2 0.2 0 0.2 -0.2 0.2 -0.3 0.3 -0.1 0.2 0 -0.1 0 -0.1 0.3 -0.1
L 0 -0.1 0 -0.5 -0.2 0.3 -0.1 0 0.6 -0.1 -0.2 -0.2 -0.1 0.5 0.1 0.2 -0.1 -0.2 0 0.2
V 0.1 -0.5 -0.3 -0.1 0 0.5 -0.1 0.2 -0.1 0.4 0.3 -0.1 0.5 0 -0.3 -0.1 0.1 -0.2 -0.3 0
M -0.3 -0.2 -0.3 -0.1 0.4 0.2 0 -0.1 0.3 0 0 -0.3 -0.1 -0.1 0 -0.1 0 0.5 -0.2 0.3
W 0.8 0 -0.1 -0.1 -0.1 -0.1 0 -0.1 -0.1 -0.2 0.3 -0.1 -0.1 -0.1 0.3 -0.3 -0.1 -0.1 -0.1 0
Y -0.2 1 0.8 0.8 0.6 0 -0.1 0.6 -0.4 0 -0.6 -0.5 0 -0.2 -0.3 -0.4 -0.6 0 -0.6 0.1
D 0.3 0.2 -0.5 0.2 0.1 -0.3 0 0 0.5 0 -0.1 0.6 0.1 -0.1 0.2 -0.6 -0.1 -0.3 -0.3 0
E 0.2 -0.1 -0.2 -0.3 0.1 0.1 -0.1 -0.1 -0.3 0.6 0.1 -0.1 0.1 0.7 0.2 0.1 -0.3 -0.2 -0.1 -0.2
K -0.1 -0.3 0.1 -0.3 -0.4 -0.2 -0.1 0.3 -0.2 -0.1 0.8 -0.2 -0.4 0.3 0.1 0.4 0.6 -0.1 -0.2 0.4
R -0.6 0 -0.1 0.2 0.3 0 -0.1 0.5 0 -0.1 0.4 0.3 0 -0.4 -0.4 -0.1 0.1 0.6 -0.2 -0.1
H -0.2 0 0.1 -0.3 -0.1 0.1 0 -0.1 0.2 -0.2 0.1 0.6 0 -0.2 -0.1 0 -0.2 -0.1 0.2 -0.1
N 0 0.1 0 0.1 0.3 -0.3 -0.1 -0.3 -0.1 -0.1 0.1 0 0.8 0 0.1 -0.2 -0.3 -0.1 0.1 -0.1
Q -0.3 -0.2 0.3 0.5 0.1 0 -0.1 0.2 0.4 0.1 0.4 -0.2 -0.2 0.4 -0.2 0.1 0 0 -0.5 -0.2
S 0.5 -0.1 0 0.2 -0.1 -0.1 -0.1 -0.3 -0.1 -0.1 0.1 -0.5 -0.6 0.1 0 0.3 0.5 0.4 0.3 -0.1
T -0.1 0.1 -0.6 0.1 0.1 0 -0.1 -0.3 -0.1 -0.3 -0.1 0.1 0.3 0.1 0.4 0.2 0.2 0 0.3 -0.2
G 0 0.2 -0.2 0.1 -0.2 -0.2 0 -0.1 -0.2 0.1 0.1 0.4 -0.1 -0.1 -0.2 0.7 -0.1 0 0.1 0.3
P -0.1 0.1 -0.2 0 0 0 0 -0.1 0.2 0.3 -0.3 -0.7 -0.3 0.1 0.1 0.7 0 0 0.6 -0.2
C 0.3 -0.1 0.3 0 -0.2 -0.2 0 -0.1 -0.3 0.2 -0.2 -0.2 -0.1 0 0.3 0.1 0.8 -0.1 -0.2 -0.1

Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0101 0.5 -0.4 -0.7 0.1 0.4 -0.6 -1.3 -0.1 0.1 0.7 0.6 0.2 -0.4 0.3 0.8 0.9 0.4 -0.6 0.8 -0.8
0104 0.4 -0.3 0.2 0.2 0 -0.2 -1.4 -0.3 0.2 0.8 0.3 0.3 -0.2 0.5 0.5 1.1 0.6 -0.3 -0.1 -1
Select residue pair below:
i_j Score Prob
0057_0094 4.155 1.00
0048_0052 2.624 1.00
0065_0093 2.598 1.00
0040_0079 2.545 1.00
0016_0096 2.512 1.00
0019_0091 2.087 1.00
0071_0079 1.919 1.00
0019_0089 1.906 1.00
0076_0080 1.896 1.00
0017_0093 1.710 1.00
0058_0096 1.642 1.00
0034_0076 1.619 1.00
0033_0076 1.571 1.00
0026_0029 1.507 1.00
0032_0043 1.500 1.00
0042_0057 1.465 1.00
0026_0050 1.401 0.99
0071_0074 1.376 0.99
0074_0079 1.373 0.99
0065_0068 1.334 0.99
0062_0095 1.333 0.99
0074_0078 1.312 0.99
0047_0052 1.298 0.99
0075_0078 1.294 0.99
0039_0062 1.265 0.99
0041_0062 1.233 0.98
0070_0073 1.230 0.98
0062_0097 1.210 0.98
0014_0098 1.203 0.98
0069_0082 1.196 0.98
0044_0059 1.188 0.98
0081_0085 1.184 0.98
0034_0040 1.176 0.98
0081_0084 1.154 0.97
0102_0107 1.147 0.97
0097_0100 1.144 0.97
0032_0076 1.138 0.97
0065_0070 1.103 0.96
0015_0064 1.102 0.96
0017_0091 1.100 0.96
0061_0096 1.087 0.96
0040_0076 1.078 0.95
0029_0051 1.071 0.95
0100_0103 1.056 0.95
0071_0082 1.048 0.94
0066_0071 1.036 0.94
0030_0044 1.028 0.94
0045_0052 1.019 0.93
0076_0084 0.990 0.92
0013_0095 0.987 0.92
0043_0046 0.984 0.92
0027_0071 0.982 0.91
0103_0106 0.979 0.91
0021_0089 0.977 0.91
0074_0077 0.968 0.91
0020_0051 0.965 0.90
0027_0083 0.960 0.90
0104_0107 0.960 0.90
0043_0059 0.951 0.90
0022_0076 0.944 0.89
0031_0080 0.930 0.88
0046_0059 0.927 0.88
0070_0074 0.911 0.87
0032_0059 0.906 0.86
0023_0026 0.903 0.86
0050_0067 0.898 0.86
0018_0056 0.891 0.85
0083_0092 0.891 0.85
0025_0053 0.870 0.83
0018_0042 0.868 0.83
0102_0106 0.861 0.82
0020_0054 0.860 0.82
0068_0091 0.856 0.82
0049_0054 0.843 0.80
0027_0090 0.840 0.80
0032_0080 0.829 0.79
0102_0105 0.823 0.78
0043_0083 0.816 0.77
0022_0086 0.806 0.76
0045_0051 0.806 0.76
0046_0049 0.803 0.76
0100_0104 0.803 0.76
0031_0034 0.797 0.75
0032_0083 0.796 0.75
0016_0056 0.795 0.75
0101_0105 0.794 0.75
0100_0106 0.792 0.74
0031_0043 0.791 0.74
0029_0044 0.789 0.74
0015_0096 0.788 0.74
0066_0082 0.781 0.73
0101_0104 0.779 0.73
0062_0080 0.772 0.72
0103_0107 0.770 0.71
0042_0063 0.762 0.70
0036_0067 0.760 0.70
0066_0084 0.759 0.70
0032_0046 0.757 0.69
0023_0050 0.756 0.69
0026_0080 0.756 0.69
0037_0049 0.748 0.68
0031_0076 0.745 0.68
0051_0057 0.745 0.68
0018_0054 0.744 0.68
0046_0052 0.740 0.67
0054_0057 0.739 0.67
0078_0081 0.733 0.66
0098_0101 0.730 0.65
0018_0094 0.728 0.65
0077_0081 0.724 0.64
0034_0060 0.712 0.63
0034_0062 0.708 0.62
0021_0025 0.706 0.62
0027_0050 0.704 0.61
0030_0046 0.691 0.59
0015_0093 0.690 0.59
0082_0086 0.690 0.59
0031_0083 0.688 0.59
0018_0063 0.687 0.58
0031_0060 0.681 0.57
0017_0065 0.677 0.57
0033_0040 0.672 0.56
0045_0067 0.670 0.56
0089_0092 0.670 0.56
0064_0070 0.661 0.54
0030_0039 0.661 0.54
0045_0059 0.658 0.54
0099_0103 0.656 0.53
0022_0043 0.655 0.53
0030_0084 0.655 0.53
0049_0055 0.649 0.52
0040_0083 0.647 0.52
0036_0043 0.642 0.51
0086_0090 0.641 0.51
0019_0063 0.640 0.50
0030_0049 0.639 0.50
0066_0087 0.637 0.50
0100_0107 0.631 0.49
0016_0094 0.623 0.48
0051_0062 0.621 0.47
0069_0085 0.620 0.47
0030_0043 0.617 0.47
0015_0095 0.616 0.46
0060_0064 0.615 0.46
0008_0011 0.612 0.46
0029_0049 0.611 0.46
0042_0061 0.610 0.45
0095_0101 0.605 0.45
Local Interactions:
i_j Score Prob
0054_0056 5.399 1.00
0070_0072 3.873 1.00
0033_0034 3.244 1.00
0023_0024 1.980 1.00
0039_0041 1.891 1.00
0106_0107 1.887 1.00
0087_0088 1.801 1.00
0037_0038 1.785 1.00
0102_0103 1.580 1.00
0104_0105 1.544 1.00
0025_0026 1.501 1.00
0103_0105 1.438 1.00
0012_0013 1.399 0.99
0105_0106 1.393 0.99
0105_0107 1.357 0.99
0090_0092 1.256 0.99
0043_0044 1.228 0.98
0008_0009 1.220 0.98
0054_0055 1.203 0.98
0014_0015 1.178 0.98
0024_0026 1.176 0.98
0027_0029 1.176 0.98
0104_0106 1.173 0.98
0009_0010 1.166 0.97
0095_0096 1.134 0.97
0016_0018 1.132 0.97
0092_0094 1.130 0.97
0049_0050 1.113 0.96
0102_0104 1.096 0.96
0101_0102 0.995 0.92
0010_0011 0.978 0.91
0100_0101 0.967 0.91
0010_0012 0.961 0.90
0023_0025 0.951 0.90
0052_0053 0.949 0.89
0086_0087 0.942 0.89
0035_0036 0.922 0.88
0101_0103 0.902 0.86
0044_0046 0.901 0.86
0087_0089 0.895 0.85
0068_0069 0.892 0.85
0040_0041 0.883 0.84
0098_0100 0.879 0.84
0008_0010 0.864 0.83
0067_0068 0.849 0.81
0100_0102 0.845 0.81
0097_0098 0.843 0.80
0103_0104 0.831 0.79
0050_0052 0.830 0.79
0036_0037 0.809 0.77
0016_0017 0.808 0.76
0026_0027 0.797 0.75
0073_0074 0.778 0.72
0013_0014 0.778 0.72
0049_0051 0.777 0.72
0022_0024 0.772 0.72
0015_0016 0.771 0.71
0011_0013 0.769 0.71
0044_0045 0.750 0.68
0015_0017 0.734 0.66
0089_0091 0.731 0.66
0088_0089 0.726 0.65
0034_0036 0.724 0.64
0043_0045 0.723 0.64
0012_0014 0.719 0.64
0098_0099 0.710 0.62
0036_0038 0.706 0.62
0034_0035 0.696 0.60
0055_0056 0.694 0.60
0085_0086 0.688 0.59
0039_0040 0.682 0.58
0024_0025 0.669 0.55
0019_0021 0.643 0.51
0059_0060 0.637 0.50
0017_0019 0.631 0.49
0099_0101 0.629 0.49
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: G S P E F ...

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