May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
VX 50-329 Return to Main Page
Instructions
  • Use the menu to the right to browse the coupling matrix.
Coupling matrix for [L:0099] and [A:0103]
- A F I L V M W Y D E K R H N Q S T G P C
A 0.7 -0.6 -0.5 -0.5 -0.1 -0.4 0.3 -0.4 0.2 0 -0.4 0.3 0.5 0.1 -0.4 0 0.3 0.8 0.6 0.2
F -0.3 -0.1 -0.1 -0.2 -0.1 -0.1 -0.1 -0.1 -0.2 1.2 0.3 -0.5 -0.2 -0.1 0.9 -0.2 -0.4 0.3 -0.1 0
I -0.1 -0.2 -0.3 -0.3 -0.2 -0.2 -0.3 -0.3 -0.3 0.5 0.3 1 -0.2 -0.2 0.5 -0.2 -0.3 0.6 0.5 -0.1
L 0 -0.2 -0.2 0.3 -0.2 -0.2 -0.3 0.2 -0.3 0.7 0.9 -0.1 0.3 0 0 -0.3 0 -0.3 -0.2 -0.1
V 0.2 -0.1 -0.1 0.2 -0.2 0.3 -0.1 0.3 -0.2 -0.1 0.5 -0.2 0.4 -0.1 -0.5 0 -0.3 -0.2 0.3 0
M 0.2 -0.2 -0.2 -0.2 -0.2 0.2 -0.2 -0.2 -0.3 -0.5 -0.1 -0.1 0.3 -0.2 -0.4 0.4 1 -0.2 0.2 0.3
W 0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.6 -0.4 0 -0.2 -0.1 1 -0.1 -0.2 -0.2 -0.1 0
Y 0 -0.2 -0.2 -0.3 -0.2 -0.2 0 -0.2 -0.3 0.6 0.6 0.7 0.1 -0.2 0.1 0 0.5 -0.4 -0.2 -0.1
D 0 0.1 0.3 0.1 0.1 -0.5 0.9 0.1 -0.4 -0.6 0.4 0.4 0 -0.2 -0.1 0 0.1 0 -0.4 0.2
E -0.3 0.4 0.8 0.2 1 0.1 1.2 -0.1 -0.5 -0.9 0.5 0.3 -0.4 0.1 -0.2 0.1 0.2 -0.2 -0.7 -0.3
K 0.7 0.1 -0.1 0.9 0.2 0.4 -1 0.6 0.6 0.1 -0.1 -0.1 0.3 -0.6 -0.6 0.3 -0.5 0 0.1 -0.3
R 0.8 0.2 0.3 0.1 -0.5 0.3 -0.6 0.1 0.8 0.4 -1.1 0 0 0.3 -0.3 0.4 0.1 -0.2 0 -0.1
H 0.1 0.4 0 0 -0.3 0 0 -0.3 -0.1 0.6 0.2 -0.3 -0.2 -0.3 0.2 0.6 0 0 -0.3 -0.1
N -0.1 -0.2 0.1 -0.3 0.7 0.5 -0.3 0.8 -0.3 -0.3 0.3 -0.2 -0.1 0.2 -0.5 -0.4 0.1 0 0.1 -0.1
Q 0.1 0.3 -0.4 0.4 0.3 0 -0.5 -0.1 1 -0.1 -0.3 -0.2 0.1 0.8 0 -0.6 0.6 -0.8 -0.4 -0.2
S -0.4 -0.2 -0.2 -0.3 -0.3 -0.3 0.5 -0.3 0.2 -0.3 -0.4 0.2 0 0.1 0.4 -0.1 0.1 1.2 0.1 -0.1
T -0.1 0.4 0.3 -0.4 0 0 -0.2 -0.1 0.5 -0.6 0.6 0.5 -0.3 -0.1 0.2 0.3 -0.1 -0.2 -0.4 -0.1
G -0.2 -0.1 -0.1 -0.1 -0.1 -0.1 0.7 -0.1 -0.1 -0.6 -0.4 -0.3 0 0.7 0.3 -0.1 -0.1 0.3 -0.1 0
P 0.1 -0.1 0.7 -0.1 -0.1 0.3 -0.1 -0.1 -0.1 -0.2 -0.4 0.1 -0.2 -0.1 0 -0.1 -0.3 -0.1 0.7 0
C 0.1 0 0 0 0 0 0 0 -0.1 0 -0.1 -0.2 -0.1 0 0.1 0 -0.1 -0.1 0 0
Conservation matrix (aka PSSM)
- A F I L V M W Y D E K R H N Q S T G P C
0099 0.9 -0.6 -0.1 -0.4 -0.4 -0.6 -0.9 -0.3 0.9 2 1.6 1 0.2 0 0.7 -0.1 0.4 -1 -0.6 -1.5
0103 2.2 -0.8 -0.5 -0.5 -0.6 -0.6 -0.8 -0.5 -0.1 1.5 1.2 1.5 0.4 -0.2 1 0.1 0.8 0.1 -0.6 -1.7
Select residue pair below:
i_j Score Prob
0064_0110 3.967 1.00
0091_0128 3.706 1.00
0102_0135 3.292 1.00
0105_0115 3.124 1.00
0269_0273 2.424 1.00
0035_0069 2.413 1.00
0098_0128 2.386 1.00
0005_0009 2.251 1.00
0106_0136 2.190 1.00
0154_0207 2.171 1.00
0087_0104 2.127 1.00
0067_0075 2.124 1.00
0014_0272 2.059 1.00
0134_0159 2.047 1.00
0044_0074 2.025 1.00
0158_0162 2.006 1.00
0210_0266 1.962 1.00
0258_0263 1.960 1.00
0159_0162 1.959 1.00
0119_0129 1.953 1.00
0102_0136 1.951 1.00
0265_0269 1.934 1.00
0127_0131 1.913 1.00
0169_0205 1.908 1.00
0032_0036 1.868 1.00
0044_0116 1.858 1.00
0259_0262 1.827 1.00
0268_0271 1.822 1.00
0153_0156 1.773 1.00
0018_0116 1.769 1.00
0087_0115 1.764 1.00
0210_0256 1.764 1.00
0134_0163 1.756 1.00
0158_0207 1.754 1.00
0166_0212 1.751 1.00
0199_0203 1.715 1.00
0214_0274 1.703 1.00
0007_0015 1.687 1.00
0248_0251 1.687 1.00
0203_0206 1.657 1.00
0199_0202 1.654 1.00
0210_0258 1.635 1.00
0131_0135 1.635 1.00
0109_0136 1.599 1.00
0051_0093 1.595 1.00
0091_0098 1.590 1.00
0246_0260 1.576 1.00
0006_0237 1.550 1.00
0148_0170 1.544 1.00
0008_0040 1.538 1.00
0103_0106 1.536 1.00
0154_0158 1.519 1.00
0267_0271 1.503 1.00
0102_0132 1.502 1.00
0028_0062 1.500 1.00
0014_0042 1.493 1.00
0143_0165 1.492 1.00
0119_0126 1.478 1.00
0098_0131 1.465 1.00
0112_0142 1.464 1.00
0043_0072 1.444 1.00
0098_0102 1.426 1.00
0101_0129 1.426 1.00
0166_0273 1.418 1.00
0202_0255 1.408 1.00
0067_0111 1.386 0.99
0161_0212 1.373 0.99
0064_0111 1.366 0.99
0099_0103 1.352 0.99
0169_0213 1.348 0.99
0016_0073 1.342 0.99
0226_0229 1.342 0.99
0017_0030 1.322 0.99
0034_0043 1.296 0.99
0032_0035 1.296 0.99
0202_0248 1.295 0.99
0127_0156 1.290 0.99
0127_0159 1.287 0.99
0157_0167 1.285 0.99
0126_0156 1.262 0.99
0106_0110 1.252 0.99
0101_0117 1.252 0.99
0117_0129 1.247 0.99
0130_0159 1.247 0.99
0035_0071 1.245 0.98
0268_0272 1.233 0.98
0209_0212 1.219 0.98
0098_0132 1.215 0.98
0146_0160 1.215 0.98
0203_0207 1.211 0.98
0004_0037 1.205 0.98
0018_0044 1.202 0.98
0191_0222 1.184 0.98
0062_0065 1.183 0.98
0030_0034 1.176 0.98
0262_0265 1.175 0.98
0126_0152 1.174 0.98
0236_0239 1.173 0.98
0247_0260 1.168 0.97
0249_0252 1.160 0.97
0015_0041 1.159 0.97
0007_0012 1.144 0.97
0037_0040 1.118 0.96
0167_0208 1.109 0.96
0208_0213 1.108 0.96
0130_0160 1.090 0.96
0144_0165 1.085 0.96
0246_0250 1.080 0.95
0006_0238 1.078 0.95
0237_0241 1.078 0.95
0105_0109 1.077 0.95
0220_0223 1.077 0.95
0065_0068 1.073 0.95
0119_0152 1.067 0.95
0019_0027 1.064 0.95
0205_0249 1.050 0.94
0021_0026 1.043 0.94
0117_0146 1.037 0.94
0016_0271 1.035 0.94
0263_0267 1.029 0.94
0145_0274 1.026 0.94
0028_0032 1.025 0.93
0030_0043 1.003 0.93
0130_0156 1.003 0.93
0004_0015 0.997 0.92
0244_0247 0.992 0.92
0053_0100 0.991 0.92
0154_0204 0.991 0.92
0109_0137 0.980 0.91
0247_0251 0.975 0.91
0045_0072 0.974 0.91
0155_0158 0.971 0.91
0004_0007 0.969 0.91
0027_0030 0.967 0.91
0031_0035 0.966 0.91
0166_0270 0.964 0.90
0170_0215 0.957 0.90
0258_0262 0.949 0.89
0064_0068 0.942 0.89
0027_0045 0.942 0.89
0166_0214 0.922 0.88
0205_0256 0.920 0.87
0245_0250 0.917 0.87
0161_0167 0.906 0.86
0166_0274 0.901 0.86
0107_0111 0.900 0.86
0029_0032 0.892 0.85
0260_0264 0.890 0.85
0213_0263 0.884 0.84
0210_0263 0.872 0.83
0005_0008 0.868 0.83
0211_0273 0.865 0.83
0118_0147 0.864 0.83
0126_0130 0.858 0.82
0191_0194 0.858 0.82
0154_0203 0.848 0.81
0130_0163 0.843 0.80
0006_0009 0.842 0.80
0064_0107 0.834 0.79
0215_0246 0.833 0.79
0031_0043 0.830 0.79
0266_0269 0.827 0.79
0006_0241 0.824 0.78
0145_0275 0.824 0.78
0214_0275 0.824 0.78
0168_0214 0.824 0.78
0095_0099 0.814 0.77
0161_0208 0.814 0.77
0169_0208 0.805 0.76
0161_0209 0.801 0.76
0105_0136 0.799 0.75
0205_0255 0.799 0.75
0095_0098 0.794 0.75
0020_0026 0.792 0.74
0006_0235 0.792 0.74
0106_0109 0.788 0.74
0119_0160 0.788 0.74
0146_0168 0.785 0.73
0017_0041 0.783 0.73
0034_0041 0.782 0.73
0075_0087 0.782 0.73
0057_0100 0.776 0.72
0152_0156 0.771 0.71
0019_0030 0.769 0.71
0046_0104 0.768 0.71
0262_0266 0.767 0.71
0201_0205 0.766 0.71
0132_0136 0.765 0.71
0215_0249 0.761 0.70
0144_0274 0.761 0.70
0243_0247 0.761 0.70
0004_0008 0.760 0.70
0213_0267 0.759 0.70
0092_0121 0.757 0.69
0038_0071 0.757 0.69
0193_0199 0.757 0.69
0237_0242 0.756 0.69
0161_0207 0.755 0.69
0109_0139 0.753 0.69
0031_0069 0.749 0.68
0053_0096 0.747 0.68
0076_0086 0.747 0.68
0100_0104 0.746 0.68
0125_0128 0.746 0.68
0159_0163 0.741 0.67
0199_0206 0.735 0.66
0272_0277 0.733 0.66
0065_0069 0.733 0.66
0031_0045 0.733 0.66
0128_0131 0.726 0.65
0027_0043 0.726 0.65
0249_0263 0.725 0.65
0118_0218 0.719 0.64
0209_0256 0.719 0.64
0028_0031 0.718 0.64
0102_0106 0.712 0.63
0214_0270 0.710 0.62
0104_0108 0.710 0.62
0090_0120 0.703 0.61
0246_0263 0.702 0.61
0016_0214 0.702 0.61
0087_0100 0.701 0.61
0148_0221 0.698 0.60
0170_0214 0.697 0.60
0269_0272 0.696 0.60
0028_0066 0.696 0.60
0148_0222 0.693 0.59
0008_0013 0.692 0.59
0227_0230 0.692 0.59
0022_0027 0.691 0.59
0016_0275 0.688 0.59
0007_0011 0.688 0.59
0256_0263 0.685 0.58
0115_0138 0.685 0.58
0206_0257 0.682 0.58
0120_0171 0.679 0.57
0246_0264 0.678 0.57
0264_0268 0.675 0.56
0003_0006 0.675 0.56
0134_0162 0.674 0.56
0016_0044 0.670 0.56
0048_0217 0.668 0.55
0013_0268 0.667 0.55
0169_0201 0.666 0.55
0145_0214 0.662 0.54
0027_0066 0.661 0.54
0109_0140 0.659 0.54
0049_0217 0.655 0.53
0108_0115 0.653 0.53
0215_0267 0.652 0.53
0258_0266 0.652 0.53
0026_0030 0.651 0.52
0201_0204 0.650 0.52
0119_0151 0.650 0.52
0208_0212 0.645 0.51
0132_0135 0.645 0.51
0061_0064 0.644 0.51
0075_0108 0.644 0.51
0018_0219 0.643 0.51
0266_0270 0.643 0.51
0012_0241 0.640 0.50
0045_0066 0.639 0.50
0126_0129 0.637 0.50
0246_0267 0.633 0.49
0004_0041 0.632 0.49
0156_0160 0.631 0.49
0142_0276 0.629 0.49
0157_0161 0.629 0.49
0147_0218 0.626 0.48
0192_0224 0.621 0.47
0073_0271 0.620 0.47
0205_0213 0.618 0.47
0048_0218 0.617 0.47
0143_0274 0.617 0.47
0090_0097 0.615 0.46
0270_0273 0.614 0.46
0086_0216 0.611 0.46
0154_0161 0.611 0.46
0112_0140 0.610 0.45
0130_0134 0.609 0.45
0126_0160 0.608 0.45
0202_0206 0.606 0.45
0109_0141 0.604 0.44
0072_0113 0.602 0.44
0109_0138 0.601 0.44
0266_0273 0.596 0.43
0245_0248 0.596 0.43
0112_0141 0.593 0.42
0219_0242 0.592 0.42
0259_0263 0.592 0.42
0227_0242 0.585 0.41
0042_0277 0.584 0.41
0261_0265 0.584 0.41
0244_0248 0.579 0.40
0034_0072 0.579 0.40
0259_0265 0.576 0.40
0087_0101 0.576 0.40
0074_0116 0.575 0.39
0206_0255 0.575 0.39
0086_0147 0.574 0.39
0042_0071 0.572 0.39
0047_0053 0.572 0.39
0033_0041 0.569 0.39
0128_0132 0.569 0.39
0051_0120 0.568 0.38
0008_0011 0.566 0.38
0127_0155 0.566 0.38
0160_0163 0.563 0.38
0105_0133 0.563 0.38
0047_0051 0.563 0.38
0220_0238 0.562 0.37
0259_0264 0.561 0.37
0062_0066 0.561 0.37
0031_0034 0.559 0.37
0007_0241 0.559 0.37
0215_0260 0.558 0.37
0027_0031 0.557 0.37
0095_0102 0.555 0.36
0096_0099 0.553 0.36
0192_0250 0.550 0.35
0115_0141 0.550 0.35
0142_0273 0.550 0.35
0119_0125 0.548 0.35
0087_0105 0.548 0.35
0221_0224 0.547 0.35
0220_0239 0.546 0.35
0086_0218 0.545 0.35
0213_0256 0.544 0.35
0035_0070 0.543 0.34
0014_0268 0.543 0.34
0089_0125 0.543 0.34
0043_0071 0.542 0.34
0116_0275 0.542 0.34
0071_0113 0.542 0.34
0057_0060 0.541 0.34
0086_0118 0.540 0.34
0137_0141 0.539 0.34
0003_0241 0.537 0.33
0223_0228 0.537 0.33
0191_0224 0.537 0.33
0235_0238 0.535 0.33
0215_0263 0.535 0.33
0068_0111 0.534 0.33
0061_0065 0.534 0.33
0263_0266 0.532 0.33
0157_0212 0.532 0.33
0191_0225 0.530 0.32
0116_0145 0.529 0.32
Local Interactions:
i_j Score Prob
0211_0212 2.342 1.00
0256_0258 2.103 1.00
0236_0238 1.948 1.00
0168_0170 1.925 1.00
0237_0238 1.925 1.00
0238_0239 1.838 1.00
0237_0239 1.772 1.00
0267_0268 1.748 1.00
0259_0261 1.682 1.00
0092_0093 1.630 1.00
0236_0237 1.612 1.00
0228_0229 1.602 1.00
0226_0228 1.575 1.00
0036_0037 1.494 1.00
0235_0237 1.451 1.00
0153_0155 1.433 1.00
0222_0224 1.399 0.99
0259_0260 1.394 0.99
0111_0112 1.388 0.99
0110_0111 1.328 0.99
0013_0014 1.223 0.98
0222_0223 1.200 0.98
0193_0194 1.195 0.98
0227_0229 1.175 0.98
0192_0193 1.171 0.98
0241_0242 1.148 0.97
0051_0052 1.142 0.97
0220_0221 1.123 0.97
0095_0096 1.109 0.96
0089_0091 1.094 0.96
0139_0140 1.074 0.95
0138_0139 1.072 0.95
0027_0028 1.063 0.95
0257_0258 1.060 0.95
0069_0070 1.035 0.94
0235_0236 1.004 0.93
0140_0141 0.998 0.92
0191_0193 0.989 0.92
0139_0141 0.985 0.92
0223_0224 0.979 0.91
0169_0170 0.971 0.91
0276_0277 0.964 0.90
0010_0011 0.963 0.90
0197_0198 0.961 0.90
0143_0144 0.960 0.90
0168_0169 0.945 0.89
0120_0121 0.941 0.89
0221_0223 0.934 0.88
0037_0038 0.926 0.88
0035_0036 0.911 0.87
0257_0259 0.899 0.86
0042_0043 0.865 0.83
0191_0192 0.864 0.83
0255_0256 0.863 0.83
0135_0136 0.862 0.82
0017_0018 0.862 0.82
0245_0246 0.854 0.82
0258_0259 0.854 0.82
0229_0230 0.817 0.77
0048_0049 0.816 0.77
0038_0040 0.813 0.77
0227_0228 0.809 0.77
0209_0211 0.799 0.75
0086_0088 0.797 0.75
0006_0007 0.793 0.74
0057_0058 0.793 0.74
0225_0226 0.766 0.71
0144_0145 0.764 0.71
0242_0243 0.763 0.70
0137_0138 0.760 0.70
0249_0250 0.750 0.68
0245_0247 0.730 0.65
0099_0100 0.728 0.65
0154_0155 0.726 0.65
0228_0230 0.725 0.65
0011_0012 0.724 0.64
0224_0225 0.724 0.64
0153_0154 0.722 0.64
0051_0053 0.719 0.64
0028_0029 0.718 0.64
0098_0099 0.718 0.64
0210_0211 0.717 0.63
0073_0074 0.714 0.63
0136_0137 0.709 0.62
0241_0243 0.697 0.60
0261_0262 0.694 0.60
0225_0227 0.692 0.59
0026_0027 0.689 0.59
0201_0202 0.676 0.57
0141_0142 0.672 0.56
0163_0165 0.669 0.55
0113_0114 0.667 0.55
0246_0247 0.667 0.55
0009_0010 0.657 0.53
0059_0061 0.656 0.53
0056_0057 0.644 0.51
0111_0113 0.640 0.50
0061_0062 0.637 0.50
0117_0119 0.636 0.50
0271_0272 0.630 0.49
0165_0167 0.629 0.49
0019_0021 0.618 0.47
0266_0267 0.618 0.47
0019_0020 0.605 0.45
0250_0251 0.600 0.44
0226_0227 0.599 0.43
0015_0017 0.599 0.43
0008_0009 0.586 0.41
0268_0269 0.576 0.40
0069_0071 0.571 0.39
0216_0217 0.569 0.39
0060_0062 0.567 0.38
0152_0153 0.563 0.38
0043_0045 0.562 0.37
0243_0244 0.562 0.37
0223_0225 0.560 0.37
0206_0207 0.557 0.37
0094_0095 0.556 0.36
0244_0245 0.552 0.36
0274_0275 0.549 0.35
0055_0056 0.545 0.35
0010_0012 0.543 0.34
0034_0035 0.543 0.34
0020_0021 0.537 0.33
0200_0201 0.532 0.33
0162_0163 0.531 0.33
See all coupling residues
Download raw data
Renumber residues to start with:
Position: 1 2 3 4 5 ...
Sequence: V R G L R ...
Page generated in 0.021 seconds.