| UniProt: | Q46801 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13051 | ||
| Length: | 159 (150) | ||
| Sequences: | 3111 | ||
| Seq/Len: | 20.74 |
| XDHC
Paralog alert: 0.66 [within 20: 0.18] - ratio of genomes with paralogs Cluster includes: XDHC YAGT |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 98_S | 154_D | 4.035 | 1.00 | |
| 128_I | 153_L | 3.884 | 1.00 | |
| 26_T | 35_Q | 3.174 | 1.00 | |
| 39_S | 79_L | 2.889 | 1.00 | |
| 131_I | 153_L | 2.826 | 1.00 | |
| 12_T | 75_E | 2.825 | 1.00 | |
| 127_T | 130_E | 2.71 | 1.00 | |
| 57_D | 74_K | 2.684 | 1.00 | |
| 89_S | 115_T | 2.626 | 1.00 | |
| 20_L | 31_L | 2.5 | 1.00 | |
| 93_Q | 97_K | 2.428 | 1.00 | |
| 98_S | 150_N | 2.154 | 1.00 | |
| 53_T | 60_A | 2.145 | 1.00 | |
| 56_V | 61_I | 2.134 | 1.00 | |
| 37_L | 40_V | 2.126 | 1.00 | |
| 47_G | 65_L | 2.111 | 1.00 | |
| 115_T | 119_A | 2.055 | 1.00 | |
| 10_E | 19_Q | 2.053 | 1.00 | |
| 123_E | 130_E | 1.998 | 1.00 | |
| 91_V | 111_I | 1.957 | 1.00 | |
| 114_T | 152_V | 1.923 | 1.00 | |
| 10_E | 17_P | 1.853 | 1.00 | |
| 12_T | 17_P | 1.849 | 1.00 | |
| 55_L | 112_M | 1.848 | 1.00 | |
| 97_K | 154_D | 1.846 | 1.00 | |
| 29_S | 42_Q | 1.845 | 1.00 | |
| 56_V | 66_Y | 1.793 | 1.00 | |
| 26_T | 31_L | 1.792 | 1.00 | |
| 42_Q | 45_C | 1.69 | 1.00 | |
| 91_V | 115_T | 1.601 | 1.00 | |
| 79_L | 111_I | 1.574 | 1.00 | |
| 39_S | 80_E | 1.572 | 1.00 | |
| 132_R | 149_V | 1.554 | 1.00 | |
| 31_L | 68_A | 1.533 | 1.00 | |
| 14_N | 80_E | 1.449 | 1.00 | |
| 135_L | 152_V | 1.431 | 1.00 | |
| 55_L | 116_A | 1.414 | 1.00 | |
| 28_L | 76_I | 1.365 | 0.99 | |
| 56_V | 76_I | 1.342 | 0.99 | |
| 60_A | 116_A | 1.335 | 0.99 | |
| 28_L | 54_V | 1.317 | 0.99 | |
| 67_L | 70_W | 1.311 | 0.99 | |
| 14_N | 37_L | 1.284 | 0.99 | |
| 91_V | 114_T | 1.278 | 0.99 | |
| 11_C | 18_F | 1.274 | 0.99 | |
| 100_A | 151_T | 1.269 | 0.99 | |
| 54_V | 63_S | 1.24 | 0.98 | |
| 146_Q | 150_N | 1.24 | 0.98 | |
| 84_K | 87_K | 1.232 | 0.98 | |
| 126_L | 156_E | 1.231 | 0.98 | |
| 116_A | 120_K | 1.228 | 0.98 | |
| 91_V | 155_C | 1.226 | 0.98 | |
| 13_I | 18_F | 1.214 | 0.98 | |
| 88_L | 92_Q | 1.209 | 0.98 | |
| 123_E | 126_L | 1.189 | 0.98 | |
| 55_L | 115_T | 1.176 | 0.98 | |
| 95_Y | 107_T | 1.154 | 0.97 | |
| 117_M | 134_G | 1.144 | 0.97 | |
| 77_R | 81_G | 1.127 | 0.97 | |
| 110_L | 135_L | 1.119 | 0.96 | |
| 118_L | 126_L | 1.113 | 0.96 | |
| 53_T | 112_M | 1.104 | 0.96 | |
| 40_V | 79_L | 1.103 | 0.96 | |
| 56_V | 71_A | 1.097 | 0.96 | |
| 56_V | 74_K | 1.096 | 0.96 | |
| 109_G | 138_N | 1.057 | 0.95 | |
| 118_L | 156_E | 1.047 | 0.94 | |
| 89_S | 92_Q | 1.041 | 0.94 | |
| 128_I | 150_N | 1.036 | 0.94 | |
| 28_L | 71_A | 1.03 | 0.94 | |
| 61_I | 66_Y | 1.003 | 0.93 | |
| 22_A | 35_Q | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3uncA | 2 | 0.9686 | 100 | 0.024 | Contact Map | 0.8 |
| 3zyvA | 4 | 0.9874 | 100 | 0.025 | Contact Map | 0.753 |
| 2w3sA | 4 | 0.9245 | 100 | 0.074 | Contact Map | 0.792 |
| 3nvwA | 2 | 0.9497 | 100 | 0.083 | Contact Map | 0.765 |
| 1dgjA | 1 | 0.956 | 100 | 0.104 | Contact Map | 0.891 |
| 1vlbA | 1 | 0.956 | 100 | 0.11 | Contact Map | 0.911 |
| 1n62A | 2 | 0.9686 | 100 | 0.161 | Contact Map | 0.883 |
| 3hrdD | 2 | 0.9686 | 100 | 0.171 | Contact Map | 0.88 |
| 1t3qA | 2 | 0.9874 | 100 | 0.225 | Contact Map | 0.842 |
| 1rm6C | 2 | 0.9623 | 100 | 0.227 | Contact Map | 0.857 |
Sequence Conservation (Image Generated using WebLogo v3)