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OPENSEQ.org

SUFA - Protein SufA
UniProt: P77667 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11378
Length: 122 (107)
Sequences: 2006
Seq/Len: 18.75

SUFA
Paralog alert: 0.68 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: ERPA ISCA SUFA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
91_E 106_H 3.98 1.00
27_H 30_E 3.196 1.00
80_P 83_A 2.826 1.00
44_G 56_V 2.644 1.00
71_E 76_K 2.629 1.00
19_T 91_E 2.588 1.00
69_L 76_K 2.58 1.00
110_A 113_E 2.463 1.00
22_P 73_D 2.422 1.00
25_A 73_D 2.254 1.00
40_G 78_F 2.179 1.00
71_E 74_G 1.977 1.00
63_P 78_F 1.935 1.00
21_T 93_D 1.845 1.00
22_P 72_H 1.754 1.00
90_T 105_F 1.747 1.00
96_R 101_Q 1.695 1.00
40_G 76_K 1.642 1.00
102_I 105_F 1.61 1.00
29_R 33_A 1.609 1.00
46_K 56_V 1.585 1.00
42_R 67_D 1.571 1.00
18_L 92_V 1.491 1.00
112_N 121_G 1.329 0.99
37_G 61_S 1.288 0.99
84_M 88_D 1.26 0.99
23_A 93_D 1.256 0.99
29_R 74_G 1.247 0.99
28_I 41_V 1.237 0.98
26_I 29_R 1.22 0.98
97_E 104_K 1.157 0.97
53_F 86_F 1.156 0.97
63_P 69_L 1.117 0.96
85_P 88_D 1.116 0.96
48_T 98_G 1.11 0.96
82_Q 85_P 1.105 0.96
98_G 103_F 1.085 0.96
21_T 24_A 1.072 0.95
51_A 121_G 1.065 0.95
27_H 31_L 1.06 0.95
95_V 100_N 1.046 0.94
20_L 28_I 1.037 0.94
90_T 118_E 1.029 0.94
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2d2aA211000.102Contact Map0.784
1nwbA10.93441000.188Contact Map0.567
1r94A20.8771000.188Contact Map0.771
1x0gA40.86891000.193Contact Map0.856
2apnA10.92621000.206Contact Map0.574
2k4zA10.967299.90.362Contact Map0.71
2p2eA10.860799.80.469Contact Map0.456
2qgoA10.860799.80.491Contact Map0.501
4g06A20.286913.80.929Contact Map0.883
3riqA10.46729.50.934Contact Map0.349

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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