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YNJC - Inner membrane ABC transporter permease protein YnjC
UniProt: P76224 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14005
Length: 511 (485)
Sequences: 1974
Seq/Len: 4.07
YNJC
Paralog alert: 0.53 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: THIP YNJC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
410_A 420_I 5.02 1.00
169_S 412_T 4.421 1.00
167_L 177_C 4.294 1.00
170_L 413_L 3.013 1.00
175_W 179_N 2.984 1.00
419_K 422_F 2.888 1.00
65_A 194_M 2.67 1.00
398_A 432_P 2.595 1.00
176_Q 180_W 2.53 1.00
173_S 176_Q 2.371 1.00
147_L 151_L 2.358 1.00
327_F 437_F 2.345 1.00
419_K 423_Y 2.334 1.00
172_Y 415_W 2.332 1.00
316_I 320_T 2.278 1.00
415_W 419_K 2.247 1.00
415_W 423_Y 2.111 1.00
63_I 133_I 2.085 1.00
205_V 224_W 2.067 1.00
318_S 445_I 2.066 1.00
165_I 408_L 2.063 1.00
147_L 193_A 2.062 1.00
72_A 147_L 2.044 1.00
416_S 419_K 1.995 1.00
171_G 414_G 1.963 1.00
55_L 59_V 1.936 1.00
67_G 140_A 1.92 1.00
180_W 423_Y 1.912 1.00
402_I 429_M 1.877 1.00
164_V 182_L 1.794 1.00
410_A 415_W 1.777 0.99
70_L 74_L 1.768 0.99
417_R 420_I 1.764 0.99
85_W 88_M 1.761 0.99
328_I 384_L 1.733 0.99
174_R 177_C 1.726 0.99
179_N 183_L 1.676 0.99
318_S 322_G 1.675 0.99
167_L 181_L 1.667 0.99
133_I 136_G 1.665 0.99
151_L 190_L 1.664 0.99
60_S 64_A 1.66 0.99
129_D 132_G 1.657 0.99
326_T 437_F 1.657 0.99
186_V 189_A 1.65 0.99
333_L 391_M 1.642 0.99
451_T 461_T 1.641 0.99
15_A 19_V 1.637 0.99
223_S 241_A 1.636 0.99
56_A 60_S 1.624 0.99
166_V 409_I 1.6 0.99
63_I 136_G 1.6 0.99
218_T 221_V 1.59 0.99
406_L 428_L 1.583 0.98
321_M 380_V 1.582 0.98
139_L 204_V 1.574 0.98
324_V 380_V 1.539 0.98
168_D 177_C 1.534 0.98
159_W 162_Q 1.532 0.98
67_G 71_I 1.516 0.98
59_V 133_I 1.506 0.98
147_L 197_I 1.495 0.98
51_P 55_L 1.492 0.98
312_S 316_I 1.489 0.98
68_A 72_A 1.469 0.97
61_T 198_V 1.468 0.97
59_V 136_G 1.459 0.97
122_P 125_T 1.456 0.97
474_S 477_I 1.439 0.97
107_A 138_T 1.438 0.97
383_H 444_G 1.433 0.97
410_A 424_V 1.428 0.97
151_L 155_L 1.424 0.96
106_S 212_G 1.422 0.96
447_Q 451_T 1.418 0.96
418_A 422_F 1.414 0.96
202_L 245_L 1.411 0.96
168_D 411_Q 1.396 0.96
73_L 186_V 1.388 0.96
327_F 331_L 1.383 0.96
383_H 451_T 1.383 0.96
322_G 445_I 1.373 0.95
420_I 424_V 1.361 0.95
283_G 286_L 1.359 0.95
41_W 243_L 1.359 0.95
375_S 378_A 1.348 0.95
72_A 76_I 1.342 0.95
407_I 425_K 1.34 0.95
315_L 319_L 1.333 0.94
176_Q 179_N 1.328 0.94
200_W 203_S 1.324 0.94
164_V 177_C 1.302 0.93
379_V 383_H 1.301 0.93
322_G 326_T 1.295 0.93
155_L 186_V 1.285 0.93
318_S 441_F 1.278 0.93
283_G 289_F 1.278 0.93
155_L 355_P 1.276 0.93
394_I 436_A 1.274 0.92
455_G 464_T 1.271 0.92
56_A 68_A 1.269 0.92
448_Y 467_V 1.265 0.92
203_S 450_P 1.259 0.92
447_Q 461_T 1.254 0.92
72_A 151_L 1.248 0.91
189_A 454_L 1.239 0.91
136_G 140_A 1.237 0.91
83_P 281_L 1.233 0.91
323_L 327_F 1.227 0.90
448_Y 461_T 1.222 0.90
254_L 262_S 1.221 0.90
322_G 444_G 1.22 0.90
62_T 66_V 1.216 0.90
219_L 241_A 1.215 0.90
120_Y 123_Y 1.208 0.90
53_A 56_A 1.2 0.89
65_A 70_L 1.2 0.89
177_C 181_L 1.199 0.89
172_Y 180_W 1.193 0.89
296_L 487_L 1.193 0.89
101_V 204_V 1.191 0.89
138_T 207_V 1.189 0.89
81_P 164_V 1.186 0.88
218_T 462_L 1.185 0.88
79_L 83_P 1.184 0.88
81_P 84_K 1.181 0.88
104_A 206_D 1.174 0.88
376_W 380_V 1.167 0.87
179_N 187_A 1.166 0.87
356_A 386_W 1.164 0.87
245_L 355_P 1.163 0.87
44_L 240_L 1.156 0.87
168_D 174_R 1.156 0.87
179_N 325_A 1.154 0.87
466_A 485_Q 1.152 0.86
176_Q 419_K 1.15 0.86
74_L 78_A 1.147 0.86
334_L 433_V 1.139 0.86
55_L 66_V 1.138 0.85
453_W 466_A 1.136 0.85
104_A 362_G 1.134 0.85
107_A 448_Y 1.133 0.85
320_T 324_V 1.127 0.85
38_L 42_Q 1.124 0.84
76_I 79_L 1.124 0.84
373_D 378_A 1.123 0.84
260_W 264_R 1.123 0.84
204_V 356_A 1.123 0.84
360_V 449_M 1.122 0.84
318_S 444_G 1.116 0.84
102_A 361_A 1.115 0.84
491_I 495_L 1.112 0.84
18_A 254_L 1.109 0.83
64_A 197_I 1.105 0.83
72_A 86_Q 1.105 0.83
218_T 222_I 1.102 0.83
181_L 424_V 1.1 0.83
67_G 136_G 1.096 0.82
21_Y 25_I 1.094 0.82
429_M 432_P 1.094 0.82
31_L 41_W 1.093 0.82
100_H 203_S 1.092 0.82
54_L 219_L 1.09 0.82
180_W 410_A 1.085 0.82
142_K 146_F 1.085 0.82
316_I 331_L 1.079 0.81
269_R 273_V 1.079 0.81
323_L 331_L 1.078 0.81
143_E 201_S 1.077 0.81
490_L 494_A 1.076 0.81
73_L 151_L 1.076 0.81
439_V 447_Q 1.076 0.81
117_L 319_L 1.075 0.81
206_D 356_A 1.071 0.80
165_I 223_S 1.071 0.80
57_T 76_I 1.07 0.80
217_P 222_I 1.067 0.80
163_Q 185_S 1.065 0.80
178_L 183_L 1.064 0.80
50_L 54_L 1.06 0.79
53_A 222_I 1.057 0.79
61_T 65_A 1.056 0.79
395_L 436_A 1.056 0.79
88_M 490_L 1.054 0.79
321_M 341_P 1.054 0.79
331_L 491_I 1.053 0.79
362_G 442_A 1.05 0.79
318_S 404_S 1.048 0.78
301_L 304_L 1.047 0.78
466_A 482_A 1.047 0.78
469_L 481_Q 1.045 0.78
391_M 440_G 1.038 0.77
27_A 362_G 1.037 0.77
395_L 429_M 1.035 0.77
377_T 380_V 1.033 0.77
333_L 392_L 1.033 0.77
405_R 408_L 1.033 0.77
440_G 444_G 1.032 0.77
175_W 182_L 1.031 0.77
336_W 339_W 1.025 0.76
115_G 118_Y 1.025 0.76
206_D 387_V 1.024 0.76
352_I 389_P 1.024 0.76
53_A 68_A 1.02 0.76
269_R 272_G 1.018 0.75
204_V 446_A 1.014 0.75
107_A 111_F 1.012 0.75
118_Y 121_F 1.011 0.75
223_S 245_L 1.011 0.75
237_K 329_A 1.007 0.74
144_S 148_L 1.007 0.74
465_E 472_G 1.002 0.74
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2onkC40.50491000.678Contact Map0.648
3d31C20.50881000.687Contact Map0.597
3rlfF10.51471000.713Contact Map0.546
3rlfG10.50881000.722Contact Map0.641
3tuiA40.405199.90.786Contact Map0.575
3qf4B10.21334.10.979Contact Map0.459
2yl4A10.17611.90.982Contact Map0.347
3qf4A10.18591.50.983Contact Map0.203
2m20A20.07051.50.984Contact Map0.413
3b60A40.1841.40.984Contact Map0.261
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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