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OPENSEQ.org
HOKA - Protein HokA
UniProt: P37305 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12346
Length: 50 (50)
Sequences: 95
Seq/Len: 1.90
HOKA
Paralog alert: 0.59 [within 20: 0.02] - ratio of genomes with paralogs
Cluster includes: HOKA HOKB HOKC HOKD HOKE MOKC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
31_L 44_L 2.479 1.00
24_I 40_L 1.933 0.98
30_E 39_E 1.743 0.96
27_S 31_L 1.7 0.96
1_M 10_L 1.38 0.85
30_E 45_A 1.302 0.80
40_L 48_L 1.259 0.76
7_L 36_E 1.243 0.75
10_L 22_W 1.243 0.75
2_P 34_K 1.206 0.72
12_V 23_M 1.176 0.69
2_P 6_R 1.172 0.69
19_F 49_K 1.158 0.67
34_K 39_E 1.149 0.67
15_F 20_F 1.128 0.64
20_F 34_K 1.107 0.62
1_M 4_K 1.091 0.61
20_F 28_L 1.086 0.60
20_F 31_L 1.074 0.59
1_M 6_R 1.064 0.58
24_I 32_H 1.063 0.58
20_F 42_A 1.049 0.56
47_K 50_E 1.038 0.55
17_L 37_S 1.037 0.55
8_L 17_L 1.023 0.53
38_Y 46_C 1.013 0.52
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
3b55A10.824.40.893Contact Map1
3dxiA20.542.50.905Contact Map0.021
4jn6A20.622.50.905Contact Map0.078
2ztjA10.562.20.909Contact Map0.044
4ixqO20.741.80.913Contact Map1
1ydnA40.581.80.913Contact Map0.05
1s94A20.621.70.914Contact Map
2voyD10.441.60.915Contact Map0.232
3w5aC10.581.60.916Contact Map0
1fjkA10.51.50.916Contact Map0.072
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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