| UniProt: | P31551 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11557 | ||
| Length: | 261 (254) | ||
| Sequences: | 13353 | ||
| Seq/Len: | 52.57 |
| CAID
Paralog alert: 0.70 [within 20: 0.25] - ratio of genomes with paralogs Cluster includes: CAID MENB PAAF PAAG SCPB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 178_R | 188_N | 3.274 | 1.00 | |
| 126_S | 164_R | 3.115 | 1.00 | |
| 123_D | 181_S | 3.107 | 1.00 | |
| 188_N | 191_E | 3.01 | 1.00 | |
| 121_C | 176_V | 2.954 | 1.00 | |
| 99_A | 116_A | 2.619 | 1.00 | |
| 15_E | 190_R | 2.594 | 1.00 | |
| 42_R | 94_D | 2.559 | 1.00 | |
| 124_N | 182_Q | 2.471 | 1.00 | |
| 163_R | 195_Q | 2.427 | 1.00 | |
| 166_G | 169_E | 2.331 | 1.00 | |
| 6_H | 19_D | 2.3 | 1.00 | |
| 157_E | 163_R | 2.226 | 1.00 | |
| 133_K | 199_S | 2.192 | 1.00 | |
| 169_E | 172_R | 2.159 | 1.00 | |
| 218_P | 221_E | 2.125 | 1.00 | |
| 39_L | 89_E | 2.111 | 1.00 | |
| 248_L | 252_E | 2.05 | 1.00 | |
| 154_I | 173_W | 2.028 | 1.00 | |
| 123_D | 168_E | 2.014 | 1.00 | |
| 184_E | 187_D | 1.978 | 1.00 | |
| 100_A | 189_A | 1.977 | 1.00 | |
| 106_F | 128_A | 1.963 | 1.00 | |
| 120_V | 180_V | 1.957 | 1.00 | |
| 159_V | 207_L | 1.954 | 1.00 | |
| 100_A | 186_M | 1.905 | 1.00 | |
| 29_K | 33_E | 1.806 | 1.00 | |
| 19_D | 55_A | 1.785 | 1.00 | |
| 14_L | 41_F | 1.782 | 1.00 | |
| 12_S | 48_R | 1.77 | 1.00 | |
| 15_E | 53_T | 1.756 | 1.00 | |
| 245_E | 254_R | 1.752 | 1.00 | |
| 157_E | 177_N | 1.747 | 1.00 | |
| 169_E | 173_W | 1.743 | 1.00 | |
| 50_A | 93_L | 1.741 | 1.00 | |
| 241_E | 261_R | 1.733 | 1.00 | |
| 17_T | 55_A | 1.733 | 1.00 | |
| 53_T | 102_N | 1.727 | 1.00 | |
| 9_R | 14_L | 1.717 | 1.00 | |
| 168_E | 172_R | 1.713 | 1.00 | |
| 123_D | 182_Q | 1.668 | 1.00 | |
| 163_R | 169_E | 1.657 | 1.00 | |
| 121_C | 127_F | 1.622 | 1.00 | |
| 120_V | 192_L | 1.622 | 1.00 | |
| 9_R | 44_D | 1.621 | 1.00 | |
| 17_T | 53_T | 1.607 | 1.00 | |
| 156_N | 212_R | 1.607 | 1.00 | |
| 113_A | 119_I | 1.607 | 1.00 | |
| 41_F | 50_A | 1.599 | 1.00 | |
| 156_N | 211_Y | 1.599 | 1.00 | |
| 157_E | 178_R | 1.591 | 1.00 | |
| 152_P | 156_N | 1.586 | 1.00 | |
| 7_L | 14_L | 1.575 | 1.00 | |
| 35_G | 89_E | 1.571 | 1.00 | |
| 156_N | 160_M | 1.527 | 1.00 | |
| 119_I | 153_A | 1.522 | 1.00 | |
| 184_E | 188_N | 1.486 | 1.00 | |
| 190_R | 194_Q | 1.478 | 1.00 | |
| 40_N | 44_D | 1.478 | 1.00 | |
| 119_I | 149_I | 1.472 | 1.00 | |
| 11_G | 194_Q | 1.472 | 1.00 | |
| 132_A | 162_G | 1.47 | 1.00 | |
| 180_V | 188_N | 1.447 | 1.00 | |
| 241_E | 259_K | 1.442 | 1.00 | |
| 90_I | 97_V | 1.44 | 1.00 | |
| 14_L | 47_L | 1.439 | 1.00 | |
| 42_R | 89_E | 1.422 | 1.00 | |
| 117_D | 208_K | 1.421 | 1.00 | |
| 18_L | 30_T | 1.414 | 1.00 | |
| 49_V | 193_A | 1.414 | 1.00 | |
| 10_N | 194_Q | 1.413 | 1.00 | |
| 27_D | 30_T | 1.406 | 0.99 | |
| 7_L | 41_F | 1.386 | 0.99 | |
| 171_L | 179_V | 1.373 | 0.99 | |
| 101_V | 105_A | 1.371 | 0.99 | |
| 16_I | 37_V | 1.367 | 0.99 | |
| 102_N | 122_A | 1.365 | 0.99 | |
| 122_A | 182_Q | 1.358 | 0.99 | |
| 10_N | 190_R | 1.351 | 0.99 | |
| 38_F | 93_L | 1.343 | 0.99 | |
| 102_N | 124_N | 1.336 | 0.99 | |
| 110_F | 129_L | 1.334 | 0.99 | |
| 209_E | 213_T | 1.332 | 0.99 | |
| 158_M | 165_M | 1.329 | 0.99 | |
| 185_L | 189_A | 1.323 | 0.99 | |
| 51_I | 189_A | 1.309 | 0.99 | |
| 186_M | 189_A | 1.298 | 0.99 | |
| 23_A | 67_K | 1.289 | 0.99 | |
| 28_A | 68_A | 1.277 | 0.99 | |
| 15_E | 186_M | 1.259 | 0.99 | |
| 91_F | 145_R | 1.256 | 0.99 | |
| 154_I | 157_E | 1.248 | 0.99 | |
| 122_A | 185_L | 1.242 | 0.98 | |
| 186_M | 190_R | 1.232 | 0.98 | |
| 50_A | 95_K | 1.23 | 0.98 | |
| 35_G | 39_L | 1.201 | 0.98 | |
| 33_E | 37_V | 1.2 | 0.98 | |
| 128_A | 164_R | 1.199 | 0.98 | |
| 154_I | 169_E | 1.179 | 0.98 | |
| 153_A | 177_N | 1.149 | 0.97 | |
| 53_T | 186_M | 1.138 | 0.97 | |
| 58_K | 102_N | 1.135 | 0.97 | |
| 167_A | 179_V | 1.125 | 0.97 | |
| 151_P | 154_I | 1.124 | 0.97 | |
| 101_V | 113_A | 1.114 | 0.96 | |
| 217_M | 221_E | 1.11 | 0.96 | |
| 88_T | 92_N | 1.109 | 0.96 | |
| 18_L | 61_S | 1.109 | 0.96 | |
| 104_Y | 126_S | 1.104 | 0.96 | |
| 61_S | 109_G | 1.103 | 0.96 | |
| 118_F | 192_L | 1.101 | 0.96 | |
| 199_S | 204_I | 1.095 | 0.96 | |
| 146_L | 150_L | 1.085 | 0.96 | |
| 67_K | 251_A | 1.084 | 0.96 | |
| 10_N | 15_E | 1.082 | 0.96 | |
| 20_R | 65_D | 1.068 | 0.95 | |
| 165_M | 173_W | 1.068 | 0.95 | |
| 150_L | 154_I | 1.061 | 0.95 | |
| 206_A | 236_S | 1.06 | 0.95 | |
| 193_A | 197_V | 1.058 | 0.95 | |
| 243_A | 247_P | 1.05 | 0.94 | |
| 143_V | 226_I | 1.046 | 0.94 | |
| 101_V | 119_I | 1.045 | 0.94 | |
| 36_E | 40_N | 1.028 | 0.94 | |
| 20_R | 23_A | 1.025 | 0.93 | |
| 6_H | 55_A | 1.021 | 0.93 | |
| 45_P | 95_K | 1.017 | 0.93 | |
| 101_V | 127_F | 1.016 | 0.93 | |
| 32_F | 83_G | 1.014 | 0.93 | |
| 189_A | 193_A | 1.013 | 0.93 | |
| 59_F | 104_Y | 1.012 | 0.93 | |
| 15_E | 51_I | 1.01 | 0.93 | |
| 8_T | 17_T | 1.008 | 0.93 | |
| 92_N | 220_E | 1.008 | 0.93 | |
| 88_T | 220_E | 1.005 | 0.93 | |
| 221_E | 224_R | 1.002 | 0.92 | |
| 168_E | 171_L | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2ej5A | 2 | 0.977 | 100 | 0.014 | Contact Map | 0.703 |
| 3qxzA | 3 | 0.977 | 100 | 0.014 | Contact Map | 0.74 |
| 3kqfA | 6 | 0.9847 | 100 | 0.016 | Contact Map | 0.827 |
| 4jfcA | 1 | 0.9732 | 100 | 0.017 | Contact Map | 0.702 |
| 3sllA | 6 | 0.9808 | 100 | 0.017 | Contact Map | 0.848 |
| 4fzwC | 2 | 0.9808 | 100 | 0.017 | Contact Map | 0.662 |
| 4lk5A | 3 | 0.9808 | 100 | 0.017 | Contact Map | 0.703 |
| 1nzyA | 2 | 0.9808 | 100 | 0.018 | Contact Map | 0.739 |
| 4jwvA | 2 | 0.9732 | 100 | 0.018 | Contact Map | 0.65 |
| 3swxA | 3 | 0.9808 | 100 | 0.021 | Contact Map | 0.763 |
Sequence Conservation (Image Generated using WebLogo v3)