| UniProt: | P11988 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10114 | ||
| Length: | 470 (458) | ||
| Sequences: | 3243 | ||
| Seq/Len: | 7.08 |
| BGLB
Paralog alert: 0.68 [within 20: 0.13] - ratio of genomes with paralogs Cluster includes: ASCB BGLA BGLB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 26_D | 101_A | 4.987 | 1.00 | |
| 111_D | 163_K | 4.119 | 1.00 | |
| 377_Q | 446_K | 4.089 | 1.00 | |
| 392_V | 402_I | 3.443 | 1.00 | |
| 107_D | 163_K | 3.343 | 1.00 | |
| 66_P | 112_E | 3.277 | 1.00 | |
| 60_D | 63_H | 3.229 | 1.00 | |
| 73_A | 116_A | 3.209 | 1.00 | |
| 124_L | 156_V | 3.203 | 1.00 | |
| 100_E | 104_A | 3.178 | 1.00 | |
| 100_E | 159_R | 3.075 | 1.00 | |
| 112_E | 115_Q | 3.053 | 1.00 | |
| 104_A | 108_R | 3.045 | 1.00 | |
| 25_E | 63_H | 2.982 | 1.00 | |
| 391_Q | 394_E | 2.974 | 1.00 | |
| 299_Y | 388_H | 2.967 | 1.00 | |
| 107_D | 159_R | 2.958 | 1.00 | |
| 235_T | 240_D | 2.767 | 1.00 | |
| 154_R | 158_T | 2.739 | 1.00 | |
| 70_A | 116_A | 2.625 | 1.00 | |
| 385_L | 407_S | 2.586 | 1.00 | |
| 69_I | 109_L | 2.582 | 1.00 | |
| 444_R | 448_F | 2.559 | 1.00 | |
| 12_G | 77_F | 2.559 | 1.00 | |
| 90_F | 155_T | 2.509 | 1.00 | |
| 66_P | 108_R | 2.455 | 1.00 | |
| 61_F | 80_L | 2.399 | 1.00 | |
| 213_C | 222_I | 2.397 | 1.00 | |
| 143_R | 284_D | 2.395 | 1.00 | |
| 429_Y | 443_T | 2.366 | 1.00 | |
| 347_N | 398_D | 2.344 | 1.00 | |
| 343_R | 398_D | 2.338 | 1.00 | |
| 101_A | 104_A | 2.283 | 1.00 | |
| 379_D | 446_K | 2.283 | 1.00 | |
| 383_A | 387_D | 2.279 | 1.00 | |
| 79_C | 406_T | 2.257 | 1.00 | |
| 211_K | 215_S | 2.159 | 1.00 | |
| 283_S | 286_E | 2.147 | 1.00 | |
| 147_D | 208_R | 2.122 | 1.00 | |
| 433_D | 437_E | 2.113 | 1.00 | |
| 61_F | 105_F | 2.083 | 1.00 | |
| 200_H | 263_Y | 2.041 | 1.00 | |
| 82_I | 110_F | 2.015 | 1.00 | |
| 154_R | 212_A | 2.013 | 1.00 | |
| 150_E | 212_A | 2.006 | 1.00 | |
| 131_Y | 135_K | 1.999 | 1.00 | |
| 114_A | 163_K | 1.998 | 1.00 | |
| 14_T | 19_V | 1.995 | 1.00 | |
| 119_K | 165_A | 1.983 | 1.00 | |
| 31_S | 87_A | 1.98 | 1.00 | |
| 107_D | 111_D | 1.965 | 1.00 | |
| 431_D | 439_S | 1.949 | 1.00 | |
| 111_D | 114_A | 1.947 | 1.00 | |
| 452_A | 456_K | 1.928 | 1.00 | |
| 82_I | 109_L | 1.894 | 1.00 | |
| 110_F | 114_A | 1.874 | 1.00 | |
| 299_Y | 341_G | 1.872 | 1.00 | |
| 23_W | 30_I | 1.869 | 1.00 | |
| 208_R | 287_D | 1.843 | 1.00 | |
| 110_F | 160_Y | 1.836 | 1.00 | |
| 453_E | 461_S | 1.815 | 1.00 | |
| 35_L | 131_Y | 1.811 | 1.00 | |
| 262_Q | 289_K | 1.806 | 1.00 | |
| 168_L | 294_F | 1.79 | 1.00 | |
| 371_E | 375_S | 1.787 | 1.00 | |
| 343_R | 347_N | 1.782 | 1.00 | |
| 69_I | 116_A | 1.777 | 1.00 | |
| 10_W | 458_R | 1.773 | 1.00 | |
| 112_E | 116_A | 1.763 | 1.00 | |
| 70_A | 112_E | 1.751 | 1.00 | |
| 113_M | 118_I | 1.748 | 1.00 | |
| 265_G | 269_R | 1.747 | 1.00 | |
| 22_A | 25_E | 1.741 | 1.00 | |
| 340_V | 391_Q | 1.729 | 1.00 | |
| 346_L | 400_V | 1.724 | 1.00 | |
| 138_G | 142_N | 1.703 | 1.00 | |
| 217_L | 220_A | 1.685 | 1.00 | |
| 232_Y | 344_V | 1.677 | 1.00 | |
| 84_I | 122_V | 1.677 | 1.00 | |
| 358_F | 403_M | 1.675 | 1.00 | |
| 119_K | 166_L | 1.647 | 1.00 | |
| 370_V | 443_T | 1.634 | 1.00 | |
| 30_I | 35_L | 1.622 | 1.00 | |
| 29_G | 93_G | 1.605 | 1.00 | |
| 343_R | 394_E | 1.586 | 1.00 | |
| 22_A | 26_D | 1.583 | 1.00 | |
| 121_L | 406_T | 1.583 | 1.00 | |
| 69_I | 112_E | 1.574 | 1.00 | |
| 79_C | 121_L | 1.573 | 1.00 | |
| 453_E | 456_K | 1.55 | 1.00 | |
| 145_V | 148_H | 1.544 | 1.00 | |
| 103_L | 155_T | 1.532 | 0.99 | |
| 213_C | 220_A | 1.526 | 0.99 | |
| 150_E | 208_R | 1.526 | 0.99 | |
| 157_F | 213_C | 1.525 | 0.99 | |
| 253_F | 267_M | 1.515 | 0.99 | |
| 60_D | 64_R | 1.507 | 0.99 | |
| 65_Y | 108_R | 1.504 | 0.99 | |
| 107_D | 160_Y | 1.5 | 0.99 | |
| 165_A | 219_E | 1.496 | 0.99 | |
| 450_W | 454_V | 1.493 | 0.99 | |
| 64_R | 67_E | 1.486 | 0.99 | |
| 162_H | 217_L | 1.48 | 0.99 | |
| 72_F | 428_I | 1.475 | 0.99 | |
| 69_I | 113_M | 1.471 | 0.99 | |
| 137_Y | 148_H | 1.447 | 0.99 | |
| 14_T | 82_I | 1.428 | 0.99 | |
| 262_Q | 268_Q | 1.425 | 0.99 | |
| 144_A | 147_D | 1.421 | 0.99 | |
| 72_F | 77_F | 1.42 | 0.99 | |
| 407_S | 427_F | 1.413 | 0.99 | |
| 444_R | 449_G | 1.405 | 0.99 | |
| 387_D | 390_V | 1.405 | 0.99 | |
| 82_I | 122_V | 1.4 | 0.99 | |
| 157_F | 209_A | 1.4 | 0.99 | |
| 346_L | 392_V | 1.397 | 0.99 | |
| 9_L | 79_C | 1.396 | 0.99 | |
| 280_M | 285_A | 1.391 | 0.99 | |
| 348_T | 352_R | 1.386 | 0.99 | |
| 74_E | 448_F | 1.386 | 0.99 | |
| 260_R | 354_Q | 1.377 | 0.99 | |
| 212_A | 215_S | 1.377 | 0.99 | |
| 14_T | 80_L | 1.373 | 0.99 | |
| 35_L | 135_K | 1.362 | 0.98 | |
| 132_G | 136_N | 1.362 | 0.98 | |
| 389_L | 392_V | 1.36 | 0.98 | |
| 451_Y | 455_I | 1.357 | 0.98 | |
| 143_R | 201_H | 1.352 | 0.98 | |
| 17_N | 55_K | 1.351 | 0.98 | |
| 199_I | 254_F | 1.341 | 0.98 | |
| 362_N | 405_Y | 1.335 | 0.98 | |
| 22_A | 63_H | 1.328 | 0.98 | |
| 154_R | 216_L | 1.326 | 0.98 | |
| 107_D | 162_H | 1.317 | 0.98 | |
| 5_P | 396_I | 1.307 | 0.98 | |
| 92_Q | 95_E | 1.302 | 0.98 | |
| 422_S | 434_D | 1.301 | 0.98 | |
| 168_L | 225_M | 1.293 | 0.98 | |
| 449_G | 452_A | 1.288 | 0.98 | |
| 453_E | 457_T | 1.287 | 0.98 | |
| 281_T | 284_D | 1.286 | 0.98 | |
| 150_E | 154_R | 1.283 | 0.97 | |
| 147_D | 150_E | 1.282 | 0.97 | |
| 124_L | 149_F | 1.279 | 0.97 | |
| 94_D | 136_N | 1.271 | 0.97 | |
| 233_P | 241_M | 1.261 | 0.97 | |
| 141_A | 194_E | 1.26 | 0.97 | |
| 110_F | 163_K | 1.257 | 0.97 | |
| 347_N | 400_V | 1.249 | 0.97 | |
| 170_F | 202_Q | 1.248 | 0.97 | |
| 29_G | 132_G | 1.247 | 0.97 | |
| 107_D | 114_A | 1.235 | 0.97 | |
| 156_V | 160_Y | 1.233 | 0.97 | |
| 208_R | 212_A | 1.233 | 0.97 | |
| 285_A | 288_L | 1.231 | 0.97 | |
| 90_F | 98_P | 1.221 | 0.96 | |
| 23_W | 28_K | 1.22 | 0.96 | |
| 224_N | 258_Q | 1.218 | 0.96 | |
| 262_Q | 354_Q | 1.216 | 0.96 | |
| 241_M | 244_A | 1.214 | 0.96 | |
| 4_F | 396_I | 1.213 | 0.96 | |
| 262_Q | 265_G | 1.211 | 0.96 | |
| 342_L | 402_I | 1.209 | 0.96 | |
| 153_A | 212_A | 1.192 | 0.96 | |
| 70_A | 74_E | 1.183 | 0.95 | |
| 210_V | 214_H | 1.182 | 0.95 | |
| 228_G | 345_L | 1.18 | 0.95 | |
| 140_W | 145_V | 1.178 | 0.95 | |
| 103_L | 159_R | 1.176 | 0.95 | |
| 84_I | 89_I | 1.175 | 0.95 | |
| 4_F | 393_N | 1.173 | 0.95 | |
| 191_G | 194_E | 1.166 | 0.95 | |
| 59_I | 411_I | 1.165 | 0.95 | |
| 342_L | 392_V | 1.159 | 0.95 | |
| 84_I | 156_V | 1.158 | 0.95 | |
| 255_G | 295_I | 1.144 | 0.94 | |
| 29_G | 91_P | 1.136 | 0.94 | |
| 282_E | 285_A | 1.133 | 0.94 | |
| 176_S | 202_Q | 1.125 | 0.94 | |
| 213_C | 218_P | 1.119 | 0.93 | |
| 61_F | 109_L | 1.118 | 0.93 | |
| 393_N | 460_L | 1.117 | 0.93 | |
| 103_L | 107_D | 1.117 | 0.93 | |
| 144_A | 148_H | 1.116 | 0.93 | |
| 121_L | 358_F | 1.116 | 0.93 | |
| 110_F | 122_V | 1.111 | 0.93 | |
| 38_H | 56_D | 1.108 | 0.93 | |
| 333_W | 365_G | 1.103 | 0.93 | |
| 393_N | 397_A | 1.095 | 0.92 | |
| 170_F | 205_A | 1.083 | 0.92 | |
| 370_V | 375_S | 1.082 | 0.92 | |
| 342_L | 359_I | 1.08 | 0.92 | |
| 142_N | 148_H | 1.073 | 0.91 | |
| 150_E | 209_A | 1.072 | 0.91 | |
| 431_D | 441_T | 1.072 | 0.91 | |
| 259_A | 355_K | 1.067 | 0.91 | |
| 166_L | 221_K | 1.067 | 0.91 | |
| 249_R | 266_Y | 1.065 | 0.91 | |
| 370_V | 376_I | 1.064 | 0.91 | |
| 27_G | 99_N | 1.063 | 0.91 | |
| 28_K | 87_A | 1.058 | 0.90 | |
| 432_R | 440_L | 1.055 | 0.90 | |
| 332_E | 367_K | 1.054 | 0.90 | |
| 155_T | 159_R | 1.045 | 0.90 | |
| 157_F | 222_I | 1.045 | 0.90 | |
| 64_R | 440_L | 1.042 | 0.90 | |
| 138_G | 141_A | 1.04 | 0.89 | |
| 70_A | 73_A | 1.038 | 0.89 | |
| 121_L | 166_L | 1.037 | 0.89 | |
| 72_F | 118_I | 1.036 | 0.89 | |
| 92_Q | 97_E | 1.029 | 0.89 | |
| 162_H | 220_A | 1.023 | 0.88 | |
| 189_E | 194_E | 1.017 | 0.88 | |
| 57_V | 432_R | 1.015 | 0.88 | |
| 103_L | 156_V | 1.015 | 0.88 | |
| 129_M | 139_G | 1.015 | 0.88 | |
| 120_P | 165_A | 1.012 | 0.88 | |
| 136_N | 144_A | 1.011 | 0.88 | |
| 228_G | 297_F | 1.01 | 0.88 | |
| 374_G | 443_T | 1.008 | 0.87 | |
| 233_P | 244_A | 1.007 | 0.87 | |
| 89_I | 155_T | 1.007 | 0.87 | |
| 340_V | 344_V | 1.007 | 0.87 | |
| 213_C | 217_L | 1.003 | 0.87 | |
| 114_A | 120_P | 1.003 | 0.87 | |
| 256_D | 260_R | 1.002 | 0.87 | |
| 350_W | 401_D | 1.001 | 0.87 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4ddeA | 2 | 0.9787 | 100 | 0.087 | Contact Map | 0.812 |
| 4iplA | 2 | 0.983 | 100 | 0.091 | Contact Map | 0.85 |
| 3qomA | 1 | 0.9745 | 100 | 0.094 | Contact Map | 0.803 |
| 1v02A | 5 | 0.9723 | 100 | 0.099 | Contact Map | 0.776 |
| 2dgaA | 1 | 0.9723 | 100 | 0.104 | Contact Map | 0.764 |
| 3ptmA | 2 | 0.9468 | 100 | 0.107 | Contact Map | 0.762 |
| 2xhyA | 4 | 0.9766 | 100 | 0.108 | Contact Map | 0.801 |
| 2jf7A | 2 | 0.9723 | 100 | 0.108 | Contact Map | 0.713 |
| 1v08A | 2 | 0.9681 | 100 | 0.109 | Contact Map | 0.787 |
| 4atdA | 2 | 0.9468 | 100 | 0.114 | Contact Map | 0.744 |
Sequence Conservation (Image Generated using WebLogo v3)