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IBPB - Small heat shock protein IbpB
UniProt: P0C058 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11535
Length: 142 (137)
Sequences: 1811
Seq/Len: 13.22

IBPB
Paralog alert: 0.57 [within 20: 0.21] - ratio of genomes with paralogs
Cluster includes: IBPA IBPB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
49_L 70_V 2.913 1.00
72_G 93_F 2.712 1.00
51_L 59_L 2.62 1.00
60_E 131_R 2.519 1.00
107_G 135_S 2.453 1.00
35_Y 97_F 2.439 1.00
55_R 112_N 2.296 1.00
60_E 71_K 2.238 1.00
41_D 44_H 2.213 1.00
50_A 114_L 2.187 1.00
50_A 88_L 2.14 1.00
71_K 94_S 2.044 1.00
51_L 110_F 2.041 1.00
36_N 88_L 2.036 1.00
44_H 118_D 1.966 1.00
35_Y 49_L 1.908 1.00
55_R 58_D 1.896 1.00
125_E 128_A 1.861 1.00
87_G 95_L 1.828 1.00
46_R 116_H 1.82 1.00
104_E 122_N 1.813 1.00
37_I 47_I 1.787 1.00
48_T 116_H 1.694 1.00
73_T 92_P 1.66 1.00
69_S 96_S 1.659 1.00
33_P 93_F 1.652 1.00
36_N 86_Q 1.625 1.00
103_M 119_L 1.607 1.00
40_S 121_R 1.575 1.00
63_L 99_L 1.559 1.00
35_Y 70_V 1.549 1.00
56_Q 112_N 1.531 1.00
68_L 117_I 1.514 1.00
36_N 50_A 1.48 1.00
59_L 110_F 1.42 1.00
41_D 46_R 1.37 0.99
87_G 91_Q 1.362 0.99
45_Y 101_E 1.357 0.99
109_T 135_S 1.325 0.99
37_I 45_Y 1.281 0.99
43_N 128_A 1.22 0.98
39_K 46_R 1.214 0.98
62_Q 69_S 1.214 0.98
31_S 72_G 1.158 0.97
32_F 36_N 1.153 0.97
55_R 111_V 1.152 0.97
72_G 91_Q 1.151 0.97
46_R 118_D 1.146 0.97
45_Y 84_L 1.127 0.97
45_Y 97_F 1.084 0.96
33_P 72_G 1.082 0.96
18_K 22_A 1.076 0.95
77_P 81_K 1.071 0.95
99_L 119_L 1.066 0.95
64_E 67_R 1.059 0.95
48_T 114_L 1.052 0.95
61_I 108_A 1.039 0.94
52_A 88_L 1.033 0.94
54_F 72_G 1.011 0.93
8_P 11_R 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4eldA20.91551000.244Contact Map0.737
3w1zA40.90141000.246Contact Map0.773
1gmeA40.94371000.265Contact Map0.736
3aabA20.83899.90.338Contact Map0.728
3glaA20.676199.90.365Contact Map0.778
4feiA10.704299.90.366Contact Map0.597
2klrA20.950799.90.394Contact Map0.52
2bolA20.929699.90.398Contact Map0.527
3l1eA10.704299.90.416Contact Map0.652
2wj5A10.690199.90.428Contact Map0.517

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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