OPENSEQ.org - ECNA - ECOLI GREMLIN

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ECNA - Entericidin A

UniProt:	P0ADB4	Sequence MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS	Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene:	EG14372
Length:	41 (41)
Sequences:	162
Seq/Len:	3.95

ECNA
Paralog alert: 0.74 [within 20: 0.34] - ratio of genomes with paralogs
Cluster includes: ECNA ECNB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Scaled Score	Prob
30_K	37_S	4.37	1.00
25_F	31_H	2.213	1.00
34_N	37_S	1.822	1.00
23_R	27_E	1.55	0.98
9_V	17_T	1.496	0.97
35_S	38_R	1.431	0.96
29_I	39_A	1.329	0.94
29_I	32_L	1.318	0.94
6_I	14_T	1.28	0.92
16_L	29_I	1.267	0.92
22_A	32_L	1.229	0.90
18_G	23_R	1.227	0.90
32_L	37_S	1.204	0.89
22_A	41_S	1.071	0.80
11_L	34_N	1.071	0.80
15_L	30_K	1.024	0.75
27_E	31_H	1.009	0.74
3_K	25_F	1.005	0.73

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling

HHsearch Results:

PDB	Chains	Cov	P(%)	HHΔ		Acc
4hd5A	1	0.9756	65.9	0.747	Contact Map
3tlkA	3	0.878	55.2	0.763	Contact Map	0
3ucpA	1	1	51.1	0.769	Contact Map	0.179
3p2nA	2	0.9756	44.1	0.778	Contact Map	0.024
3qaxA	2	1	37.2	0.788	Contact Map	0.085
4k3vA	2	0.9268	35.3	0.79	Contact Map	0
3pmqA	1	0.9756	33.4	0.793	Contact Map
4av2M	12	0.8537	33	0.793	Contact Map
2qgmA	1	1	32.6	0.793	Contact Map	0.5
1w5cT	2	1	29.6	0.798	Contact Map	0.175

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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