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OPENSEQ.org
YEEZ - Protein YeeZ
UniProt: P0AD12 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13393
Length: 274 (267)
Sequences: 27969
Seq/Len: 104.75
YEEZ
Paralog alert: 0.91 [within 20: 0.64] - ratio of genomes with paralogs
Cluster includes: FCL GALE GM4D HLDD QOR2 RMLB1 RMLB2 RMLD YBJS YEEZ YFCH YRAR
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
196_A 212_I 2.905 1.00
19_S 195_G 2.832 1.00
3_K 26_Q 2.713 1.00
210_Y 258_E 2.63 1.00
256_C 262_E 2.401 1.00
208_H 254_R 2.358 1.00
71_A 201_L 2.346 1.00
195_G 264_Q 2.334 1.00
30_S 50_L 2.251 1.00
86_E 90_Q 2.242 1.00
59_D 62_D 2.237 1.00
253_S 257_N 2.211 1.00
50_L 62_D 2.107 1.00
221_N 225_P 2.1 1.00
6_I 17_A 2.098 1.00
106_R 153_S 2.091 1.00
64_D 101_A 2.077 1.00
110_T 197_I 2.072 1.00
19_S 198_T 2.009 1.00
229_R 269_L 1.991 1.00
219_A 222_V 1.979 1.00
5_A 69_A 1.959 1.00
19_S 23_R 1.922 1.00
23_R 202_Q 1.909 1.00
124_K 127_T 1.899 1.00
157_L 200_L 1.897 1.00
226_Q 229_R 1.841 1.00
3_K 28_T 1.825 1.00
28_T 69_A 1.821 1.00
74_I 109_F 1.82 1.00
7_V 74_I 1.801 1.00
73_V 201_L 1.792 1.00
93_Q 97_D 1.787 1.00
60_S 97_D 1.769 1.00
28_T 46_D 1.749 1.00
195_G 199_L 1.749 1.00
222_V 225_P 1.746 1.00
16_L 73_V 1.733 1.00
70_D 105_P 1.732 1.00
16_L 194_I 1.723 1.00
28_T 48_Y 1.721 1.00
226_Q 230_L 1.698 1.00
146_L 154_V 1.668 1.00
93_Q 145_W 1.658 1.00
159_L 197_I 1.633 1.00
4_V 25_W 1.588 1.00
226_Q 269_L 1.586 1.00
111_S 115_V 1.586 1.00
140_E 144_D 1.585 1.00
19_S 22_A 1.562 1.00
16_L 75_T 1.556 1.00
26_Q 46_D 1.543 1.00
157_L 197_I 1.539 1.00
198_T 202_Q 1.523 1.00
106_R 155_D 1.51 1.00
12_L 162_L 1.509 1.00
267_D 270_V 1.504 1.00
135_S 139_L 1.491 1.00
17_A 29_G 1.467 1.00
116_Y 211_N 1.465 1.00
129_R 140_E 1.464 1.00
85_D 141_E 1.455 1.00
215_P 256_C 1.454 1.00
90_Q 93_Q 1.441 1.00
255_I 259_L 1.437 1.00
159_L 193_V 1.411 1.00
92_V 142_L 1.402 0.99
51_R 58_C 1.392 0.99
58_C 86_E 1.38 0.99
199_L 203_A 1.378 0.99
184_G 217_H 1.377 0.99
72_L 99_A 1.368 0.99
97_D 100_L 1.359 0.99
19_S 194_I 1.35 0.99
73_V 197_I 1.341 0.99
252_G 256_C 1.337 0.99
125_E 254_R 1.322 0.99
64_D 98_S 1.319 0.99
23_R 198_T 1.314 0.99
20_L 198_T 1.314 0.99
124_K 251_D 1.307 0.99
188_V 193_V 1.291 0.99
60_S 94_E 1.28 0.99
189_H 265_Y 1.278 0.99
144_D 147_H 1.277 0.99
110_T 159_L 1.273 0.99
95_L 107_I 1.27 0.99
158_R 209_I 1.252 0.99
190_L 194_I 1.247 0.99
62_D 65_A 1.243 0.98
147_H 156_I 1.239 0.98
74_I 92_V 1.225 0.98
25_W 202_Q 1.221 0.98
75_T 110_T 1.22 0.98
18_M 166_G 1.219 0.98
52_M 91_A 1.219 0.98
52_M 76_L 1.213 0.98
137_R 141_E 1.212 0.98
99_A 107_I 1.205 0.98
252_G 263_Y 1.204 0.98
182_E 221_N 1.204 0.98
208_H 258_E 1.2 0.98
195_G 261_F 1.198 0.98
160_A 250_I 1.197 0.98
97_D 101_A 1.194 0.98
186_N 215_P 1.193 0.98
11_W 164_G 1.191 0.98
254_R 258_E 1.189 0.98
4_V 71_A 1.18 0.98
15_P 191_E 1.17 0.97
98_S 102_H 1.168 0.97
182_E 219_A 1.163 0.97
143_E 158_R 1.152 0.97
5_A 30_S 1.152 0.97
19_S 191_E 1.144 0.97
3_K 70_D 1.143 0.97
123_V 127_T 1.142 0.97
96_V 149_L 1.136 0.97
177_T 237_Q 1.126 0.97
99_A 104_I 1.122 0.97
18_M 22_A 1.118 0.96
196_A 255_I 1.112 0.96
145_W 148_N 1.111 0.96
228_A 234_E 1.103 0.96
29_G 45_I 1.099 0.96
147_H 154_V 1.096 0.96
225_P 228_A 1.096 0.96
121_G 124_K 1.095 0.96
147_H 209_I 1.092 0.96
109_F 142_L 1.088 0.96
163_V 271_M 1.087 0.96
160_A 213_C 1.087 0.96
14_M 166_G 1.082 0.96
221_N 238_F 1.081 0.95
163_V 189_H 1.08 0.95
107_I 146_L 1.074 0.95
199_L 259_L 1.067 0.95
88_Y 138_V 1.062 0.95
96_V 107_I 1.062 0.95
126_T 254_R 1.059 0.95
60_S 64_D 1.05 0.94
121_G 127_T 1.049 0.94
210_Y 254_R 1.031 0.94
4_V 20_L 1.03 0.94
11_W 190_L 1.021 0.93
87_F 91_A 1.021 0.93
158_R 211_N 1.02 0.93
15_P 190_L 1.01 0.93
109_F 156_I 1.009 0.93
113_T 160_A 1.007 0.93
16_L 20_L 1.004 0.93
90_Q 94_E 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1sb8A10.97811000.162Contact Map0.739
2c20A60.98181000.166Contact Map0.846
1oc2A20.97811000.166Contact Map0.8
3m2pA60.96351000.167Contact Map0.815
1rkxA40.97811000.167Contact Map0.795
3rufA40.97811000.17Contact Map0.794
2yy7A20.96721000.17Contact Map0.831
2pzmA20.97081000.172Contact Map0.752
2c5aA20.97451000.175Contact Map0.814
1orrA40.97811000.175Contact Map0.798
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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