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OPENSEQ.org
ROB - Right origin-binding protein
UniProt: P0ACI0 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11366
Length: 289 (288)
Sequences: 1052
Seq/Len: 3.65
ROB
Paralog alert: 0.52 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: ROB YKGA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
17_H 20_Q 4.491 1.00
135_D 221_G 3.062 1.00
62_S 88_F 2.848 1.00
135_D 218_M 2.749 1.00
25_D 35_K 2.366 1.00
254_T 288_R 2.337 1.00
227_F 243_V 2.299 1.00
65_A 80_Y 2.225 1.00
42_F 53_Y 2.191 1.00
65_A 79_Q 2.179 1.00
84_S 87_T 2.087 1.00
85_Q 89_T 2.049 1.00
69_T 104_R 2.016 1.00
66_L 73_I 1.99 1.00
71_R 76_I 1.927 1.00
247_C 251_L 1.924 1.00
137_P 216_P 1.9 1.00
10_L 38_L 1.892 1.00
10_L 27_V 1.881 1.00
240_I 283_L 1.877 1.00
128_H 227_F 1.834 0.99
89_T 99_T 1.83 0.99
72_P 75_D 1.816 0.99
14_L 54_I 1.807 0.99
222_G 256_R 1.794 0.99
228_T 282_E 1.733 0.99
23_S 26_N 1.706 0.99
15_E 53_Y 1.694 0.99
229_Y 239_F 1.678 0.99
78_L 85_Q 1.658 0.99
223_E 253_L 1.652 0.99
6_I 32_G 1.634 0.99
248_M 255_R 1.633 0.99
239_F 243_V 1.609 0.98
76_I 104_R 1.582 0.98
26_N 29_A 1.555 0.98
10_L 30_K 1.542 0.98
15_E 57_R 1.526 0.97
230_E 280_R 1.522 0.97
142_T 197_F 1.519 0.97
27_V 30_K 1.514 0.97
132_T 223_E 1.511 0.97
248_M 251_L 1.493 0.97
182_N 262_E 1.49 0.97
23_S 82_F 1.477 0.97
13_W 17_H 1.468 0.97
69_T 76_I 1.463 0.96
180_G 198_Y 1.459 0.96
19_D 61_K 1.449 0.96
163_F 167_F 1.438 0.96
74_L 78_L 1.435 0.96
53_Y 57_R 1.434 0.96
177_V 263_R 1.427 0.96
180_G 264_Y 1.425 0.96
244_Y 255_R 1.408 0.95
133_L 136_T 1.402 0.95
129_K 226_M 1.331 0.93
116_P 120_L 1.326 0.93
65_A 71_R 1.31 0.92
263_R 282_E 1.291 0.92
131_V 226_M 1.288 0.92
6_I 10_L 1.286 0.91
17_H 223_E 1.275 0.91
37_H 40_R 1.268 0.91
274_D 279_L 1.265 0.91
136_T 219_L 1.248 0.90
224_Y 258_G 1.243 0.90
74_L 85_Q 1.229 0.89
180_G 262_E 1.229 0.89
24_L 35_K 1.228 0.89
60_S 140_G 1.227 0.89
14_L 27_V 1.219 0.88
139_I 214_G 1.216 0.88
164_W 168_L 1.21 0.88
225_V 247_C 1.204 0.87
138_L 199_T 1.201 0.87
14_L 22_L 1.199 0.87
48_H 56_A 1.192 0.87
89_T 100_P 1.186 0.86
43_K 49_A 1.179 0.86
140_G 199_T 1.168 0.85
13_W 18_L 1.16 0.85
28_A 49_A 1.154 0.84
25_D 29_A 1.151 0.84
274_D 277_I 1.146 0.84
120_L 164_W 1.145 0.84
132_T 221_G 1.13 0.83
249_P 282_E 1.13 0.83
60_S 96_F 1.129 0.82
265_Y 280_R 1.118 0.82
212_L 234_T 1.114 0.81
33_Y 41_M 1.112 0.81
140_G 217_V 1.112 0.81
27_V 73_I 1.112 0.81
54_I 73_I 1.111 0.81
190_K 193_E 1.111 0.81
59_L 95_Q 1.111 0.81
243_V 285_I 1.109 0.81
199_T 204_Q 1.102 0.80
7_I 46_T 1.098 0.80
147_C 194_Q 1.087 0.79
239_F 283_L 1.085 0.79
71_R 79_Q 1.084 0.79
4_A 8_R 1.083 0.79
14_L 247_C 1.082 0.79
85_Q 101_A 1.081 0.79
184_T 195_E 1.079 0.78
20_Q 26_N 1.077 0.78
33_Y 36_W 1.074 0.78
142_T 215_H 1.073 0.78
143_Q 166_D 1.073 0.78
82_F 96_F 1.072 0.78
33_Y 82_F 1.071 0.78
47_G 241_L 1.067 0.77
156_R 164_W 1.06 0.77
240_I 281_C 1.055 0.76
266_P 279_L 1.054 0.76
249_P 252_N 1.051 0.76
84_S 259_Q 1.049 0.76
52_A 55_R 1.049 0.76
17_H 36_W 1.044 0.75
133_L 224_Y 1.041 0.75
53_Y 60_S 1.039 0.75
48_H 60_S 1.038 0.74
5_G 9_D 1.035 0.74
50_I 93_K 1.035 0.74
35_K 43_K 1.029 0.74
14_L 18_L 1.029 0.74
28_A 63_A 1.018 0.72
133_L 261_I 1.017 0.72
135_D 158_E 1.017 0.72
256_R 288_R 1.014 0.72
56_A 95_Q 1.013 0.72
59_L 243_V 1.013 0.72
194_Q 201_A 1.006 0.71
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1d5yA40.98961000.319Contact Map0.588
4fe7A10.38751000.638Contact Map0.607
3gbgA10.38751000.638Contact Map0.502
1bl0A10.42561000.65Contact Map0.579
3oioA10.38411000.652Contact Map0.579
2k9sA10.36681000.653Contact Map0.485
3mn2A20.36681000.655Contact Map0.58
3oouA10.37371000.655Contact Map0.627
3w6vA10.394599.90.656Contact Map0.63
3lsgA50.352999.90.658Contact Map0.722
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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